ATE154636T1 - Dopamin-rezeptoren und gene - Google Patents

Dopamin-rezeptoren und gene

Info

Publication number
ATE154636T1
ATE154636T1 AT90901227T AT90901227T ATE154636T1 AT E154636 T1 ATE154636 T1 AT E154636T1 AT 90901227 T AT90901227 T AT 90901227T AT 90901227 T AT90901227 T AT 90901227T AT E154636 T1 ATE154636 T1 AT E154636T1
Authority
AT
Austria
Prior art keywords
methods
well
dopamine receptor
labeled
genes
Prior art date
Application number
AT90901227T
Other languages
English (en)
Inventor
Olivier Civelli
James R Bunzow
David K Grandy
Curtis A Machida
Original Assignee
Oregon State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oregon State filed Critical Oregon State
Application granted granted Critical
Publication of ATE154636T1 publication Critical patent/ATE154636T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/286—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against neuromediator receptors, e.g. serotonin receptor, dopamine receptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT90901227T 1988-11-18 1989-11-20 Dopamin-rezeptoren und gene ATE154636T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27337388A 1988-11-18 1988-11-18

Publications (1)

Publication Number Publication Date
ATE154636T1 true ATE154636T1 (de) 1997-07-15

Family

ID=23043636

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90901227T ATE154636T1 (de) 1988-11-18 1989-11-20 Dopamin-rezeptoren und gene

Country Status (6)

Country Link
EP (1) EP0447483B1 (de)
JP (3) JP3018045B2 (de)
AT (1) ATE154636T1 (de)
DE (1) DE68928137T2 (de)
ES (1) ES2104599T3 (de)
WO (1) WO1990005780A1 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931841A1 (de) * 1989-09-23 1991-04-04 Basf Ag Dopamin-d2-rezeptor
EP0514490B1 (de) * 1990-02-07 1996-06-26 Board Of Regents, The University Of Texas System Allelische verbindung des humanen dopamin-(d2)rezeptor-gens in kompulsionsstörungen wie alkoholismus
AU8066591A (en) * 1990-05-14 1991-12-10 Duke University Cloned genes encoding the d1 dopamine receptor
AU8403191A (en) * 1990-07-06 1992-02-04 United States of America, as represented by the Secretary, U.S. Department of Commerce, The A cdna encoding the rat d1 dopamine receptor linked to adenylyl cyclase activation and expression product
AU8427291A (en) * 1990-07-10 1992-02-04 Neurogenetic Corporation Nucleic acid sequences encoding a human dopamine d1 receptor
ES2157197T3 (es) 1990-09-13 2001-08-16 Univ Duke Expresion de receptores acoplados a una proteina g en levadura.
US5215915A (en) * 1991-04-16 1993-06-01 Duke University Cloned gene encoding rat d1b dopamine receptor
US5245011A (en) * 1991-04-16 1993-09-14 Duke University Aqueous solution containing D1B dopamine receptor
EP0673252A4 (de) * 1992-12-14 1998-07-15 Start Technology Partnership Verwendung von zur dopamin-rezeptor-mrna antisensen oligonukleotiden zur diagnose und behandlung von neurologischen pathologien.
US7235648B1 (en) 1993-03-31 2007-06-26 Cadus Technologies, Inc. Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
US6100042A (en) 1993-03-31 2000-08-08 Cadus Pharmaceutical Corporation Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
US20030054402A1 (en) 1993-03-31 2003-03-20 Cadus Pharmaceutical Corporation Methods and compositions for identifying receptor effectors
US6255059B1 (en) 1993-03-31 2001-07-03 Cadus Pharmaceutical Corporation Methods for identifying G protein coupled receptor effectors
AU1176095A (en) * 1993-11-10 1995-05-29 University Of British Columbia, The Method of treatment using, process of preparing, and composition comprising a recombinant hsv-1
FR2733514A1 (fr) * 1995-04-26 1996-10-31 Inst Nat Sante Rech Med Animal transgenique non humain dans lequel l'expression du recepteur d2 est modifiee
US5686255A (en) * 1995-05-24 1997-11-11 Deth; Richard C. Compositions and methods for diagnosing schizophrenia
US5738998A (en) * 1995-05-24 1998-04-14 Deth; Richard C. Compositions and methods for diagnosing schizophrenia
US5723315A (en) * 1996-08-23 1998-03-03 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US5708157A (en) * 1996-07-26 1998-01-13 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US5654173A (en) * 1996-08-23 1997-08-05 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US5728819A (en) * 1996-08-02 1998-03-17 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US5985602A (en) * 1996-08-14 1999-11-16 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US5945302A (en) * 1996-04-05 1999-08-31 Genetics Institute, Inc. Polynucleotides encoding secreted proteins
US5965388A (en) * 1996-07-09 1999-10-12 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1998001469A2 (en) * 1996-06-19 1998-01-15 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
EP0912735A2 (de) * 1996-07-09 1999-05-06 Genetics Institute, Inc. Sekretierte proteine und polynucleotide die für diese kodieren
EP0937143A2 (de) * 1996-07-26 1999-08-25 Genetics Institute, Inc. Sekretierte polypeptide und die dafür kodierenden polynucleotide
WO1998004696A1 (en) * 1996-07-26 1998-02-05 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1998004695A1 (en) * 1996-07-26 1998-02-05 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1998005781A1 (en) * 1996-08-02 1998-02-12 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
AU3986497A (en) * 1996-08-23 1998-03-06 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
AU4746397A (en) * 1996-10-04 1998-04-24 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
AU4670297A (en) * 1996-10-04 1998-04-24 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
AU4809497A (en) * 1996-10-04 1998-04-24 Genetics Institute Inc. Secreted proteins
WO1998017687A2 (en) * 1996-10-25 1998-04-30 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
CA2241911A1 (en) * 1996-11-01 1998-05-14 Genetics Institute, Inc. Secreted proteins
CA2275535A1 (en) * 1996-11-06 1998-05-14 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
CA2270873A1 (en) * 1996-11-15 1998-05-22 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
AU5516498A (en) * 1996-12-06 1998-06-29 Genetics Institute Inc. Secreted proteins and polynucleotides encoding them
JP2002513279A (ja) * 1997-01-09 2002-05-08 ジェネティックス・インスチチュート・インコーポレーテッド 分泌蛋白およびそれらをコードするポリヌクレオチド
CA2278104A1 (en) * 1997-01-13 1998-07-16 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1998031802A2 (en) * 1997-01-21 1998-07-23 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
JP2001523950A (ja) * 1997-01-24 2001-11-27 ジェネティックス・インスチチュート・インコーポレーテッド 分泌蛋白およびそれらをコードするポリヌクレオチド
US5965397A (en) * 1997-01-31 1999-10-12 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
EP0971950A2 (de) * 1997-02-24 2000-01-19 Genetics Institute, Inc. Sekretierte proteine und fuer diese kodierende polynukleotide
US5976837A (en) * 1997-03-14 1999-11-02 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
US6080549A (en) * 1997-04-08 2000-06-27 Northeastern University Methods and materials for the diagnosis and treatment of schizophrenia and related disorders
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JP3430332B2 (ja) 2003-07-28
JP2000083690A (ja) 2000-03-28
EP0447483B1 (de) 1997-06-18
ES2104599T3 (es) 1997-10-16
JPH04506449A (ja) 1992-11-12
EP0447483A1 (de) 1991-09-25
DE68928137T2 (de) 1998-02-19
JP3018045B2 (ja) 2000-03-13
WO1990005780A1 (en) 1990-05-31
EP0447483A4 (en) 1992-07-08
JPH11285400A (ja) 1999-10-19
DE68928137D1 (de) 1997-07-24
JP4122403B2 (ja) 2008-07-23

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee