ATE153078T1 - Methode zur sequenzierung kurzer oligonukleotide - Google Patents

Methode zur sequenzierung kurzer oligonukleotide

Info

Publication number
ATE153078T1
ATE153078T1 AT95909358T AT95909358T ATE153078T1 AT E153078 T1 ATE153078 T1 AT E153078T1 AT 95909358 T AT95909358 T AT 95909358T AT 95909358 T AT95909358 T AT 95909358T AT E153078 T1 ATE153078 T1 AT E153078T1
Authority
AT
Austria
Prior art keywords
oligonucleotide
primer
extension products
auxiliary
chain
Prior art date
Application number
AT95909358T
Other languages
English (en)
Inventor
Aharon S Cohen
Alexei Belenky
Christopher M Ott
Original Assignee
Hybridon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybridon Inc filed Critical Hybridon Inc
Application granted granted Critical
Publication of ATE153078T1 publication Critical patent/ATE153078T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6862—Ligase chain reaction [LCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
AT95909358T 1994-01-26 1995-01-24 Methode zur sequenzierung kurzer oligonukleotide ATE153078T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/187,749 US5525470A (en) 1994-01-26 1994-01-26 Method of sequencing [short] oligonucleotides

Publications (1)

Publication Number Publication Date
ATE153078T1 true ATE153078T1 (de) 1997-05-15

Family

ID=22690308

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95909358T ATE153078T1 (de) 1994-01-26 1995-01-24 Methode zur sequenzierung kurzer oligonukleotide

Country Status (8)

Country Link
US (1) US5525470A (de)
EP (1) EP0741799B1 (de)
JP (1) JPH09508282A (de)
AT (1) ATE153078T1 (de)
AU (1) AU1734695A (de)
CA (1) CA2180722A1 (de)
DE (1) DE69500303T2 (de)
WO (1) WO1995020680A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997025444A1 (en) * 1996-01-16 1997-07-17 Hybridon, Inc. Method of monitoring pharmacokinetics of oligonucleotide pharmaceuticals
US5851804A (en) * 1996-05-06 1998-12-22 Apollon, Inc. Chimeric kanamycin resistance gene
US6291164B1 (en) 1996-11-22 2001-09-18 Invitrogen Corporation Methods for preventing inhibition of nucleic acid synthesis by pyrophosphate
AU6553498A (en) * 1997-03-14 1998-09-29 Hybridon, Inc. Method for sequencing of modified nucleic acids using electrospray ionization-fourier transform mass spectrometry
US5888778A (en) * 1997-06-16 1999-03-30 Exact Laboratories, Inc. High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers
US20040038206A1 (en) * 2001-03-14 2004-02-26 Jia Zhang Method for high throughput assay of genetic analysis
AU2003279089A1 (en) * 2002-09-30 2004-04-19 Parallele Bioscience, Inc. Polynucleotide synthesis and labeling by kinetic sampling ligation
US20040219565A1 (en) 2002-10-21 2004-11-04 Sakari Kauppinen Oligonucleotides useful for detecting and analyzing nucleic acids of interest
CA2796924C (en) * 2002-11-25 2016-12-13 Nonprofit Organization Translational Research Organization Of Duchenne Muscular Dystrophy Ena nucleic acid pharmaceuticals capable of modifying splicing of mrna precursors
US20090186343A1 (en) * 2003-01-28 2009-07-23 Visigen Biotechnologies, Inc. Methods for preparing modified biomolecules, modified biomolecules and methods for using same
US8192937B2 (en) * 2004-04-07 2012-06-05 Exiqon A/S Methods for quantification of microRNAs and small interfering RNAs
US9109256B2 (en) 2004-10-27 2015-08-18 Esoterix Genetic Laboratories, Llc Method for monitoring disease progression or recurrence
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
US20080045472A1 (en) * 2006-03-31 2008-02-21 Council Of Scientific And Industrial Research Bharat Biotech Targets for human micro rnas in avian influenza virus (h5n1) genome
WO2020239822A1 (en) * 2019-05-27 2020-12-03 The European Molecular Biology Laboratory Nucleic acid construct binding to influenza polymerase pb1 rna synthesis active site

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE58908694D1 (de) * 1988-05-24 1995-01-12 Biotechnolog Forschung Gmbh Oligonucleotidbank und verfahren zur dna-sequenzierung.
US5403709A (en) * 1992-10-06 1995-04-04 Hybridon, Inc. Method for sequencing synthetic oligonucleotides containing non-phosphodiester internucleotide linkages

Also Published As

Publication number Publication date
EP0741799A1 (de) 1996-11-13
JPH09508282A (ja) 1997-08-26
US5525470A (en) 1996-06-11
WO1995020680A1 (en) 1995-08-03
CA2180722A1 (en) 1995-08-03
EP0741799B1 (de) 1997-05-14
DE69500303D1 (de) 1997-06-19
AU1734695A (en) 1995-08-15
DE69500303T2 (de) 1997-10-30

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