ATE150005T1 - Verbesserte ioversol-synthese - Google Patents

Verbesserte ioversol-synthese

Info

Publication number
ATE150005T1
ATE150005T1 AT93911018T AT93911018T ATE150005T1 AT E150005 T1 ATE150005 T1 AT E150005T1 AT 93911018 T AT93911018 T AT 93911018T AT 93911018 T AT93911018 T AT 93911018T AT E150005 T1 ATE150005 T1 AT E150005T1
Authority
AT
Austria
Prior art keywords
ioversol
synthesis
improved
acetoxyacetamido
diacetoxypropyl
Prior art date
Application number
AT93911018T
Other languages
English (en)
Inventor
Allan R Bailey
Shard S Sathe
Andre T Spears
Richard C Wisneski
Mills T Kneller
Original Assignee
Mallinckrodt Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Medical Inc filed Critical Mallinckrodt Medical Inc
Application granted granted Critical
Publication of ATE150005T1 publication Critical patent/ATE150005T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT93911018T 1992-05-15 1993-05-03 Verbesserte ioversol-synthese ATE150005T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US88376092A 1992-05-15 1992-05-15

Publications (1)

Publication Number Publication Date
ATE150005T1 true ATE150005T1 (de) 1997-03-15

Family

ID=25383289

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93911018T ATE150005T1 (de) 1992-05-15 1993-05-03 Verbesserte ioversol-synthese

Country Status (9)

Country Link
US (1) US5489708A (de)
EP (1) EP0640067B1 (de)
JP (1) JPH07506835A (de)
AT (1) ATE150005T1 (de)
AU (1) AU4230893A (de)
CA (1) CA2134653A1 (de)
DE (1) DE69308839T2 (de)
ES (1) ES2102031T3 (de)
WO (1) WO1993023365A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4230893A (en) * 1992-05-15 1993-12-13 Mallinckrodt Medical, Inc. Improved synthesis of ioversol
TWI288654B (en) * 2001-05-17 2007-10-21 Ind Tech Res Inst Process for the purification of water-soluble non-ionic contrast agents
US7959211B2 (en) * 2008-08-25 2011-06-14 Control Solutions LLC Sensor installations for motorized vehicle doors
US7938376B2 (en) * 2008-08-22 2011-05-10 Control Solutions LLC Mounting clips and sensor installations for motorized vehicle doors
FR3084668A1 (fr) 2018-08-02 2020-02-07 Guerbet Procede de preparation monotope de composes organo-iodes intermediaires a la synthese du ioversol
CN115160174A (zh) * 2022-07-09 2022-10-11 浙江海洲制药有限公司 一种碘佛醇的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US503587A (en) * 1893-08-22 Process of making smokeless explosives
US5035877A (en) * 1985-08-09 1991-07-30 Cook Imaging Corporation Non-ionic contrast media from ionic contrast media
DE3739098A1 (de) * 1987-11-16 1989-05-24 Schering Ag Neue substituierte dicarbonsaeure-bis(3,5-dicarbamoyl-2,4,6- trijod-anilide), verfahren zu deren herstellung sowie diese enthaltende roentgenkontrastmittel
US5043152A (en) * 1988-06-02 1991-08-27 Guerbet S.A. Novel iodinated non-ionic triiodobenzene compounds and contrast media containing them
US4997983A (en) * 1990-01-31 1991-03-05 Mallinckrodt, Inc. Process for production of ioversol
US5019371A (en) * 1990-11-21 1991-05-28 Mallinckrodt Medical, Inc. Novel x-ray contrast agents, compositions and methods
AU4230893A (en) * 1992-05-15 1993-12-13 Mallinckrodt Medical, Inc. Improved synthesis of ioversol

Also Published As

Publication number Publication date
WO1993023365A1 (en) 1993-11-25
AU4230893A (en) 1993-12-13
CA2134653A1 (en) 1993-11-25
US5489708A (en) 1996-02-06
DE69308839D1 (de) 1997-04-17
DE69308839T2 (de) 1997-07-24
EP0640067B1 (de) 1997-03-12
JPH07506835A (ja) 1995-07-27
EP0640067A1 (de) 1995-03-01
ES2102031T3 (es) 1997-07-16
EP0640067A4 (de) 1995-05-31

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Legal Events

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