ATE148229T1 - Verfahren und vorrichtung zur untersuchung des reaktionsmusters von zellen/zellaggregaten während der perfusion durch ein testmedium - Google Patents

Verfahren und vorrichtung zur untersuchung des reaktionsmusters von zellen/zellaggregaten während der perfusion durch ein testmedium

Info

Publication number
ATE148229T1
ATE148229T1 AT90915212T AT90915212T ATE148229T1 AT E148229 T1 ATE148229 T1 AT E148229T1 AT 90915212 T AT90915212 T AT 90915212T AT 90915212 T AT90915212 T AT 90915212T AT E148229 T1 ATE148229 T1 AT E148229T1
Authority
AT
Austria
Prior art keywords
space
cell
medium
control medium
pct
Prior art date
Application number
AT90915212T
Other languages
English (en)
Inventor
Gunnar Engstroem
Original Assignee
Gunnar Engstroem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gunnar Engstroem filed Critical Gunnar Engstroem
Application granted granted Critical
Publication of ATE148229T1 publication Critical patent/ATE148229T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Sustainable Development (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT90915212T 1989-10-05 1990-10-05 Verfahren und vorrichtung zur untersuchung des reaktionsmusters von zellen/zellaggregaten während der perfusion durch ein testmedium ATE148229T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8903274A SE464763B (sv) 1989-10-05 1989-10-05 Metod och anordning foer att studera cellers/cellaggregats reaktionsmoenster vid perfusion med ett testmedium

Publications (1)

Publication Number Publication Date
ATE148229T1 true ATE148229T1 (de) 1997-02-15

Family

ID=20377062

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90915212T ATE148229T1 (de) 1989-10-05 1990-10-05 Verfahren und vorrichtung zur untersuchung des reaktionsmusters von zellen/zellaggregaten während der perfusion durch ein testmedium

Country Status (7)

Country Link
US (1) US5312731A (de)
EP (1) EP0495847B1 (de)
AT (1) ATE148229T1 (de)
AU (1) AU6529290A (de)
DE (1) DE69029807T2 (de)
SE (1) SE464763B (de)
WO (1) WO1991005253A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3067347B2 (ja) * 1991-10-30 2000-07-17 株式会社島津製作所 ゲル状ビーズの選別装置
US5721135A (en) * 1995-07-06 1998-02-24 Novo Nordisk A/S Apparatus for identifying biologically active substances by their effect on living cells
WO1997014962A1 (en) * 1995-10-18 1997-04-24 John Hopkins University Dosage modeling system
US5962317A (en) * 1995-10-18 1999-10-05 The Johns Hopkins University School Of Medicine Dosage modeling system
US6287848B1 (en) 1995-10-18 2001-09-11 Johns Hopkins University Dosage modeling system
US6762036B2 (en) * 1995-11-08 2004-07-13 Trustees Of Boston University Cellular physiology workstations for automated data acquisition and perfusion control
WO1997017426A1 (en) * 1995-11-08 1997-05-15 Trustees Of Boston University Cellular physiology workstations for automated data acquisition and perfusion control
WO1997036166A1 (en) * 1996-03-25 1997-10-02 Diasys Corporation Apparatus and method for handling fluid samples of body materials
US5942443A (en) * 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US20060000722A1 (en) * 1996-06-28 2006-01-05 Caliper Life Sciences, Inc. High throughput screening assay systems in microscale fluidic devices
CA2258489C (en) * 1996-06-28 2004-01-27 Caliper Technologies Corporation High-throughput screening assay systems in microscale fluidic devices
CN1310980A (zh) * 2000-02-29 2001-09-05 迪亚西斯公司 处理各种体液的方法和设备
AU2002230396B2 (en) * 2000-10-06 2012-06-07 Krstec, Victor System and method to simulate hemodynamics
US6864065B2 (en) * 2000-11-08 2005-03-08 Surface Logix, Inc. Assays for monitoring cell motility in real-time
US7326563B2 (en) 2000-11-08 2008-02-05 Surface Logix, Inc. Device and method for monitoring leukocyte migration
US7033819B2 (en) 2000-11-08 2006-04-25 Surface Logix, Inc. System for monitoring cell motility in real-time
US6893851B2 (en) 2000-11-08 2005-05-17 Surface Logix, Inc. Method for arraying biomolecules and for monitoring cell motility in real-time
US6699665B1 (en) * 2000-11-08 2004-03-02 Surface Logix, Inc. Multiple array system for integrating bioarrays
US7374906B2 (en) 2000-11-08 2008-05-20 Surface Logix, Inc. Biological assays using gradients formed in microfluidic systems
US7033821B2 (en) * 2000-11-08 2006-04-25 Surface Logix, Inc. Device for monitoring cell motility in real-time
US6844184B2 (en) * 2000-11-08 2005-01-18 Surface Logix, Inc. Device for arraying biomolecules and for monitoring cell motility in real-time
AU2003228950A1 (en) * 2002-05-08 2003-11-11 Scion Pharmaceuticals, Inc. Oocyte recording chamber
TWM352684U (en) * 2008-09-26 2009-03-11 Shanghai Microtek Technology Co Ltd Inspection apparatus for biological sample
KR102291945B1 (ko) 2017-02-02 2021-08-23 패스트 코포레이션 미생물의 운동성 운동학의 분석 및 사용

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1187970A (en) * 1912-04-09 1916-06-20 Nathan Augustus Cobb Mechanical microscope-stage.
US2942520A (en) * 1955-12-20 1960-06-28 George G Rose Tissue culture device
US2940360A (en) * 1957-05-23 1960-06-14 Jr William H Carter Perfusion chamber
US3031924A (en) * 1959-03-12 1962-05-01 James C Lamal Observation slide
US3029695A (en) * 1960-05-02 1962-04-17 Frank E Wolf Microscope slides
US3065669A (en) * 1960-07-19 1962-11-27 American Cyanamid Co Tissue culture chamber
GB1064244A (en) * 1965-01-05 1967-04-05 Ici Ltd Cell culture slides
US3620596A (en) * 1970-09-18 1971-11-16 Aerojet General Co Microscope slides
US3726597A (en) * 1972-03-09 1973-04-10 Us Health Education & Welfare Controlled environment culture system for light microscopy
FR2178555A5 (de) * 1972-12-21 1973-11-09 Petroles Cie Francaise
SE448881B (sv) * 1981-03-12 1987-03-23 Erik Walum Apparat for genomforandet av perfusionsodling av en eller flera cellkulturer samt forfarande for perfusionsodling av en eller flera cellkulturer
US4395492A (en) * 1981-06-03 1983-07-26 Res-Del Group Ltd. Perfusion chamber
US4435508A (en) * 1981-11-20 1984-03-06 Gabridge Michael G Tissue culture vessel
US4734372A (en) * 1983-02-04 1988-03-29 Brown University Research Foundation Cell culturing methods and apparatus
US4559299A (en) * 1983-02-04 1985-12-17 Brown University Research Foundation Inc. Cytotoxicity assays in cell culturing devices
DE3317551A1 (de) * 1983-05-13 1984-11-15 Stephan Dipl.-Chem. Dr.rer.nat. 8000 München Nees Perfusionseinrichtung zum "in vitro"-bespuelen verankerungsabhaengiger biologischer zellsysteme
US4647531A (en) * 1984-02-06 1987-03-03 Ortho Diagnostic Systems, Inc. Generalized cytometry instrument and methods of use
US4748124A (en) * 1984-10-30 1988-05-31 E. I. Du Pont De Nemours And Company Compartmentalized cell-culture device and method
US4681853A (en) * 1985-10-23 1987-07-21 Hardy Kenneth J Perfusion slit chamber for filter-bound sample analyses
US4680266A (en) * 1985-11-21 1987-07-14 Contraves Ag Cell culture chamber with means for automatic replenishment of nutrient

Also Published As

Publication number Publication date
AU6529290A (en) 1991-04-28
WO1991005253A1 (en) 1991-04-18
DE69029807T2 (de) 1997-05-28
EP0495847A1 (de) 1992-07-29
US5312731A (en) 1994-05-17
SE8903274L (sv) 1991-04-06
SE8903274D0 (sv) 1989-10-05
SE464763B (sv) 1991-06-10
EP0495847B1 (de) 1997-01-22
DE69029807D1 (de) 1997-03-06

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