ATE144769T1 - Prostaglandin e1-analoge - Google Patents
Prostaglandin e1-analogeInfo
- Publication number
- ATE144769T1 ATE144769T1 AT92908246T AT92908246T ATE144769T1 AT E144769 T1 ATE144769 T1 AT E144769T1 AT 92908246 T AT92908246 T AT 92908246T AT 92908246 T AT92908246 T AT 92908246T AT E144769 T1 ATE144769 T1 AT E144769T1
- Authority
- AT
- Austria
- Prior art keywords
- prostaglandin
- analogue
- ethynylene
- chem
- aryl
- Prior art date
Links
- 150000003165 prostaglandin E1 derivatives Chemical class 0.000 title abstract 2
- GMVPRGQOIOIIMI-UHFFFAOYSA-N (8R,11R,12R,13E,15S)-11,15-Dihydroxy-9-oxo-13-prostenoic acid Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CCCCCCC(O)=O GMVPRGQOIOIIMI-UHFFFAOYSA-N 0.000 abstract 1
- 206010067484 Adverse reaction Diseases 0.000 abstract 1
- 230000006838 adverse reaction Effects 0.000 abstract 1
- 229960000711 alprostadil Drugs 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000005678 ethenylene group Chemical group [H]C([*:1])=C([H])[*:2] 0.000 abstract 1
- 125000005677 ethinylene group Chemical group [*:2]C#C[*:1] 0.000 abstract 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- GMVPRGQOIOIIMI-DWKJAMRDSA-N prostaglandin E1 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DWKJAMRDSA-N 0.000 abstract 1
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18211291 | 1991-04-22 | ||
| JP29673991 | 1991-08-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE144769T1 true ATE144769T1 (de) | 1996-11-15 |
Family
ID=26501037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92908246T ATE144769T1 (de) | 1991-04-22 | 1992-04-21 | Prostaglandin e1-analoge |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5639899A (de) |
| EP (2) | EP0597095B1 (de) |
| KR (1) | KR100205279B1 (de) |
| AT (1) | ATE144769T1 (de) |
| AU (2) | AU657952B2 (de) |
| CA (2) | CA2109109A1 (de) |
| DE (1) | DE69214953T2 (de) |
| ES (1) | ES2099822T3 (de) |
| WO (2) | WO1992018472A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2109109A1 (en) * | 1991-04-22 | 1992-10-23 | Fumie Sato | Prostaglandin e1 analogues |
| EP0627416B1 (de) * | 1992-02-05 | 1998-05-13 | Nissan Chemical Industries Ltd. | Verfahren zur herstellung von prostaglandin e |
| JP3316018B2 (ja) | 1992-03-13 | 2002-08-19 | 大正製薬株式会社 | Ｅ型プロスタグランジン類またはそのエステルの製造方法 |
| CA2140853A1 (en) * | 1992-07-24 | 1994-02-03 | Takehiro Amano | Prostaglandin derivatives |
| JP3534433B2 (ja) | 1992-10-19 | 2004-06-07 | 大正製薬株式会社 | 血小板凝集阻害剤 |
| JP3479985B2 (ja) | 1992-10-20 | 2003-12-15 | 大正製薬株式会社 | 血小板凝集阻害剤 |
| CA2147461A1 (en) * | 1992-10-21 | 1994-04-28 | Takehiro Amano | Prostaglandin e1 analogues |
| CA2156304A1 (en) * | 1993-02-19 | 1994-09-01 | Fumie Sato | Process for producing intermediate for 13,14-didehydroprostaglandin e |
| US5645637A (en) * | 1994-05-30 | 1997-07-08 | Baran Advanced Materials 94 Ltd. | Foamed magnesite cement and articles made therewith |
| CA2334355C (en) | 1998-05-25 | 2009-01-27 | Taisho Pharmaceutical Co., Ltd. | Prostaglandin derivatives |
| PL3456710T3 (pl) * | 2016-05-09 | 2021-12-20 | AGC Inc. | Nowa pochodna prostaglandyny |
| JP6705974B2 (ja) * | 2017-11-08 | 2020-06-03 | Ａｇｃ株式会社 | 新規なプロスタグランジン誘導体を有効成分として含有する医薬 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1409637A (en) * | 1972-04-14 | 1975-10-08 | Searle & Co | Pentaneheptanoic acid derivatives |
| IT1049373B (it) * | 1975-03-21 | 1981-01-20 | Erba Carlo Spa | Fluoro prostaglandine |
| AU501803B2 (en) * | 1975-03-21 | 1979-06-28 | Farmitalia Carlo Erba S.P.A. | Fluoro-prostaglandins |
| ZA77160B (en) * | 1976-02-13 | 1977-11-30 | Upjohn Co | Prostaglandin analogs |
| US4018803A (en) * | 1976-02-13 | 1977-04-19 | The Upjohn Company | 13,14-Didehydro-PG3 compounds |
| US4029681A (en) * | 1976-02-13 | 1977-06-14 | The Upjohn Company | 13,14-Didehydro-PG analogs |
| US4086258A (en) * | 1976-02-17 | 1978-04-25 | The Upjohn Company | 13,14-Didehydro-PGA1 compounds |
| ZA77159B (en) * | 1976-02-17 | 1977-11-30 | Smith H | Prostaglandin analogs |
| DE2635985A1 (de) * | 1976-08-06 | 1978-02-09 | Schering Ag | Prostansaeurederivat und verfahren zu ihrer herstellung |
| US4205179A (en) * | 1978-04-05 | 1980-05-27 | The Upjohn Company | Trans-2,3,13,14-tetradehydro-9-deoxy-9-methylene-PGF compounds |
| US4325970A (en) * | 1980-10-09 | 1982-04-20 | Hoffmann-La Roche Inc. | 15-Acetyl-prostaglandins |
| CA2109109A1 (en) * | 1991-04-22 | 1992-10-23 | Fumie Sato | Prostaglandin e1 analogues |
| EP0627416B1 (de) * | 1992-02-05 | 1998-05-13 | Nissan Chemical Industries Ltd. | Verfahren zur herstellung von prostaglandin e |
| US5545666A (en) * | 1992-10-20 | 1996-08-13 | Taisho Pharmaceutical Co., Ltd. | Prostaglandin derivatives |
| WO1994008960A1 (en) * | 1992-10-20 | 1994-04-28 | Taisho Pharmaceutical Co., Ltd. | Prostaglandin e1 analog |
| CA2147461A1 (en) * | 1992-10-21 | 1994-04-28 | Takehiro Amano | Prostaglandin e1 analogues |
-
1992
- 1992-04-21 CA CA002109109A patent/CA2109109A1/en not_active Abandoned
- 1992-04-21 ES ES92908246T patent/ES2099822T3/es not_active Expired - Lifetime
- 1992-04-21 US US08/133,171 patent/US5639899A/en not_active Expired - Fee Related
- 1992-04-21 AU AU15489/92A patent/AU657952B2/en not_active Ceased
- 1992-04-21 CA CA002109110A patent/CA2109110C/en not_active Expired - Fee Related
- 1992-04-21 EP EP92908246A patent/EP0597095B1/de not_active Expired - Lifetime
- 1992-04-21 KR KR1019930703198A patent/KR100205279B1/ko not_active IP Right Cessation
- 1992-04-21 WO PCT/JP1992/000513 patent/WO1992018472A1/ja active IP Right Grant
- 1992-04-21 EP EP19920908341 patent/EP0591532A4/de not_active Ceased
- 1992-04-21 AT AT92908246T patent/ATE144769T1/de not_active IP Right Cessation
- 1992-04-21 DE DE69214953T patent/DE69214953T2/de not_active Expired - Fee Related
- 1992-04-21 US US08/137,090 patent/US5449815A/en not_active Expired - Fee Related
- 1992-04-21 WO PCT/JP1992/000514 patent/WO1992018473A1/ja not_active Application Discontinuation
- 1992-04-21 AU AU15537/92A patent/AU657953B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU657952B2 (en) | 1995-03-30 |
| US5639899A (en) | 1997-06-17 |
| CA2109110C (en) | 2003-03-18 |
| EP0591532A1 (de) | 1994-04-13 |
| ES2099822T3 (es) | 1997-06-01 |
| WO1992018473A1 (fr) | 1992-10-29 |
| DE69214953T2 (de) | 1997-02-20 |
| WO1992018472A1 (en) | 1992-10-29 |
| DE69214953D1 (de) | 1996-12-05 |
| AU657953B2 (en) | 1995-03-30 |
| CA2109109A1 (en) | 1992-10-23 |
| CA2109110A1 (en) | 1992-10-23 |
| EP0591532A4 (de) | 1994-11-09 |
| EP0597095A1 (de) | 1994-05-18 |
| US5449815A (en) | 1995-09-12 |
| KR100205279B1 (ko) | 1999-07-01 |
| EP0597095B1 (de) | 1996-10-30 |
| AU1553792A (en) | 1992-11-17 |
| EP0597095A4 (de) | 1994-11-09 |
| AU1548992A (en) | 1992-11-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |