ATE143360T1 - Neue pyrrolidinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel - Google Patents

Neue pyrrolidinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Info

Publication number
ATE143360T1
ATE143360T1 AT92403404T AT92403404T ATE143360T1 AT E143360 T1 ATE143360 T1 AT E143360T1 AT 92403404 T AT92403404 T AT 92403404T AT 92403404 T AT92403404 T AT 92403404T AT E143360 T1 ATE143360 T1 AT E143360T1
Authority
AT
Austria
Prior art keywords
products containing
medicinal products
production
containing same
pyrrolidine derivatives
Prior art date
Application number
AT92403404T
Other languages
English (en)
Inventor
Gilbert Lavielle
Patrick Hautefaye
Michel Laubie
Tony Verbeuren
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of ATE143360T1 publication Critical patent/ATE143360T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT92403404T 1991-12-20 1992-12-15 Neue pyrrolidinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel ATE143360T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9115851A FR2685325B1 (fr) 1991-12-20 1991-12-20 Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (1)

Publication Number Publication Date
ATE143360T1 true ATE143360T1 (de) 1996-10-15

Family

ID=9420272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92403404T ATE143360T1 (de) 1991-12-20 1992-12-15 Neue pyrrolidinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Country Status (13)

Country Link
US (1) US5296494A (de)
EP (1) EP0549407B1 (de)
JP (1) JPH0678302B2 (de)
AT (1) ATE143360T1 (de)
AU (1) AU651262B2 (de)
CA (1) CA2085570C (de)
DE (1) DE69214113T2 (de)
DK (1) DK0549407T3 (de)
ES (1) ES2094324T3 (de)
FR (1) FR2685325B1 (de)
GR (1) GR3021766T3 (de)
NZ (1) NZ245519A (de)
ZA (1) ZA929855B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2687146B1 (fr) * 1992-02-12 1994-04-01 Adir Cie Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
HUT69381A (en) * 1993-12-09 1995-09-28 Egyt Gyogyszervegyeszeti Gyar Process for producing (2-chloro pyridyl)-7-azabicyclo [2.2.1.]heptane
US5792776A (en) * 1994-06-27 1998-08-11 Cytomed, Inc., Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5856309A (en) * 1994-10-14 1999-01-05 Boehringer Mannheim Gmbh Amidinopyrroline derivatives, processes for their production and pharmaceutical agents containing these compounds
US6124341A (en) * 1996-02-13 2000-09-26 Abbott Laboratories Endothelin antagonists
TW575561B (en) 1999-03-25 2004-02-11 Hoffmann La Roche 1-arenesulfonyl-2-aryl-pyrrolidine and piperidine derivatives
AU2001264729A1 (en) * 2000-05-22 2001-12-03 Nitromed, Inc. Thromboxane inhibitors, compositions and methods of use related applications
CN103214407B (zh) * 2013-05-07 2015-11-18 北京大学 制备四氢吡咯类衍生物的方法
ES2885551T3 (es) * 2014-12-15 2021-12-14 Univ California Agentes antiarrítmicos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2054729T3 (es) * 1987-05-01 1994-08-16 Fujisawa Pharmaceutical Co Derivados de pirrolidina.
JPH0798795B2 (ja) * 1987-05-08 1995-10-25 塩野義製薬株式会社 スルホンアミド置換不飽和脂肪酸
EP0312906A3 (de) * 1987-10-23 1990-09-05 Ono Pharmaceutical Co., Ltd. Sulfonamidderivate
US5130323A (en) * 1988-10-31 1992-07-14 Fujisawa Pharmaceutical Co., Ltd. Pyrrolidine derivatives
FR2687146B1 (fr) * 1992-02-12 1994-04-01 Adir Cie Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
NZ245519A (en) 1994-08-26
DE69214113D1 (de) 1996-10-31
CA2085570C (fr) 2001-10-23
US5296494A (en) 1994-03-22
FR2685325A1 (fr) 1993-06-25
ES2094324T3 (es) 1997-01-16
GR3021766T3 (en) 1997-02-28
EP0549407A1 (de) 1993-06-30
JPH05262723A (ja) 1993-10-12
DE69214113T2 (de) 1997-04-10
AU3020492A (en) 1993-06-24
FR2685325B1 (fr) 1994-02-04
DK0549407T3 (de) 1997-03-10
AU651262B2 (en) 1994-07-14
EP0549407B1 (de) 1996-09-25
ZA929855B (en) 1994-01-13
CA2085570A1 (fr) 1993-06-21
JPH0678302B2 (ja) 1994-10-05

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee