DK0549407T3 - - Google Patents
Info
- Publication number
- DK0549407T3 DK0549407T3 DK92403404.4T DK92403404T DK0549407T3 DK 0549407 T3 DK0549407 T3 DK 0549407T3 DK 92403404 T DK92403404 T DK 92403404T DK 0549407 T3 DK0549407 T3 DK 0549407T3
- Authority
- DK
- Denmark
- Prior art keywords
- thromboxane
- afflictions
- thrombotic
- prevention
- compounds
- Prior art date
Links
- 102000003938 Thromboxane Receptors Human genes 0.000 abstract 1
- 108090000300 Thromboxane Receptors Proteins 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000001732 thrombotic effect Effects 0.000 abstract 1
- DSNBHJFQCNUKMA-SCKDECHMSA-N thromboxane A2 Chemical compound OC(=O)CCC\C=C/C[C@@H]1[C@@H](/C=C/[C@@H](O)CCCCC)O[C@@H]2O[C@H]1C2 DSNBHJFQCNUKMA-SCKDECHMSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9115851A FR2685325B1 (fr) | 1991-12-20 | 1991-12-20 | Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0549407T3 true DK0549407T3 (da) | 1997-03-10 |
Family
ID=9420272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92403404.4T DK0549407T3 (da) | 1991-12-20 | 1992-12-15 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5296494A (da) |
| EP (1) | EP0549407B1 (da) |
| JP (1) | JPH0678302B2 (da) |
| AT (1) | ATE143360T1 (da) |
| AU (1) | AU651262B2 (da) |
| CA (1) | CA2085570C (da) |
| DE (1) | DE69214113T2 (da) |
| DK (1) | DK0549407T3 (da) |
| ES (1) | ES2094324T3 (da) |
| FR (1) | FR2685325B1 (da) |
| GR (1) | GR3021766T3 (da) |
| NZ (1) | NZ245519A (da) |
| ZA (1) | ZA929855B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2687146B1 (fr) * | 1992-02-12 | 1994-04-01 | Adir Cie | Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| HUT69381A (en) * | 1993-12-09 | 1995-09-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing (2-chloro pyridyl)-7-azabicyclo [2.2.1.]heptane |
| US5792776A (en) * | 1994-06-27 | 1998-08-11 | Cytomed, Inc., | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders |
| US5856309A (en) * | 1994-10-14 | 1999-01-05 | Boehringer Mannheim Gmbh | Amidinopyrroline derivatives, processes for their production and pharmaceutical agents containing these compounds |
| US6124341A (en) * | 1996-02-13 | 2000-09-26 | Abbott Laboratories | Endothelin antagonists |
| TW575561B (en) * | 1999-03-25 | 2004-02-11 | Hoffmann La Roche | 1-arenesulfonyl-2-aryl-pyrrolidine and piperidine derivatives |
| WO2001089519A1 (en) * | 2000-05-22 | 2001-11-29 | Nitromed, Inc. | Thromboxane inhibitors, compositions and methods of use related applications |
| CN103214407B (zh) * | 2013-05-07 | 2015-11-18 | 北京大学 | 制备四氢吡咯类衍生物的方法 |
| WO2016100379A1 (en) * | 2014-12-15 | 2016-06-23 | The Regents Of The University Of California | Anti-arrhythmicity agents |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH24950A (en) * | 1987-05-01 | 1990-12-26 | Fujisawa Pharmaceutical Co | Pyrrolidine derivatives and pharmaceutical compositions containing the same |
| JPH0798795B2 (ja) * | 1987-05-08 | 1995-10-25 | 塩野義製薬株式会社 | スルホンアミド置換不飽和脂肪酸 |
| EP0312906A3 (en) * | 1987-10-23 | 1990-09-05 | Ono Pharmaceutical Co., Ltd. | Novel sulfonamide derivatives |
| US5130323A (en) * | 1988-10-31 | 1992-07-14 | Fujisawa Pharmaceutical Co., Ltd. | Pyrrolidine derivatives |
| FR2687146B1 (fr) * | 1992-02-12 | 1994-04-01 | Adir Cie | Nouveaux derives de pyrrolidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
-
1991
- 1991-12-20 FR FR9115851A patent/FR2685325B1/fr not_active Expired - Fee Related
-
1992
- 1992-12-15 AT AT92403404T patent/ATE143360T1/de not_active IP Right Cessation
- 1992-12-15 DK DK92403404.4T patent/DK0549407T3/da active
- 1992-12-15 DE DE69214113T patent/DE69214113T2/de not_active Expired - Fee Related
- 1992-12-15 EP EP92403404A patent/EP0549407B1/fr not_active Expired - Lifetime
- 1992-12-15 ES ES92403404T patent/ES2094324T3/es not_active Expired - Lifetime
- 1992-12-16 CA CA002085570A patent/CA2085570C/fr not_active Expired - Fee Related
- 1992-12-17 AU AU30204/92A patent/AU651262B2/en not_active Ceased
- 1992-12-18 NZ NZ245519A patent/NZ245519A/en unknown
- 1992-12-18 ZA ZA929855A patent/ZA929855B/xx unknown
- 1992-12-18 US US07/992,930 patent/US5296494A/en not_active Expired - Fee Related
- 1992-12-21 JP JP4340769A patent/JPH0678302B2/ja not_active Expired - Lifetime
-
1996
- 1996-11-22 GR GR960403157T patent/GR3021766T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0678302B2 (ja) | 1994-10-05 |
| FR2685325A1 (fr) | 1993-06-25 |
| AU3020492A (en) | 1993-06-24 |
| EP0549407A1 (fr) | 1993-06-30 |
| NZ245519A (en) | 1994-08-26 |
| CA2085570C (fr) | 2001-10-23 |
| DE69214113D1 (de) | 1996-10-31 |
| JPH05262723A (ja) | 1993-10-12 |
| GR3021766T3 (en) | 1997-02-28 |
| CA2085570A1 (fr) | 1993-06-21 |
| DE69214113T2 (de) | 1997-04-10 |
| ES2094324T3 (es) | 1997-01-16 |
| US5296494A (en) | 1994-03-22 |
| FR2685325B1 (fr) | 1994-02-04 |
| AU651262B2 (en) | 1994-07-14 |
| EP0549407B1 (fr) | 1996-09-25 |
| ATE143360T1 (de) | 1996-10-15 |
| ZA929855B (en) | 1994-01-13 |
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