ATE142878T1 - Verwendung der 3-indolbrenztraubensäure zur erniedrigung der glucocorticoidblutspiegel und zur vorbeugung cerebraler störungen - Google Patents

Verwendung der 3-indolbrenztraubensäure zur erniedrigung der glucocorticoidblutspiegel und zur vorbeugung cerebraler störungen

Info

Publication number
ATE142878T1
ATE142878T1 AT93830530T AT93830530T ATE142878T1 AT E142878 T1 ATE142878 T1 AT E142878T1 AT 93830530 T AT93830530 T AT 93830530T AT 93830530 T AT93830530 T AT 93830530T AT E142878 T1 ATE142878 T1 AT E142878T1
Authority
AT
Austria
Prior art keywords
acid
indolepyrugenic
blood levels
cerebral disorders
prevent cerebral
Prior art date
Application number
AT93830530T
Other languages
English (en)
Inventor
Vincenzo Politi
Mario Materazzi
Stazio Giovanni Di
Luca Giovanna De
Original Assignee
Polifarma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polifarma Spa filed Critical Polifarma Spa
Application granted granted Critical
Publication of ATE142878T1 publication Critical patent/ATE142878T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
AT93830530T 1993-01-25 1993-12-29 Verwendung der 3-indolbrenztraubensäure zur erniedrigung der glucocorticoidblutspiegel und zur vorbeugung cerebraler störungen ATE142878T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM930034A IT1261165B (it) 1993-01-25 1993-01-25 Agente attivo per ridurre il livello ematico di glucocorticoidi e prevenire disturbi cerebrali da stress e senilita'.

Publications (1)

Publication Number Publication Date
ATE142878T1 true ATE142878T1 (de) 1996-10-15

Family

ID=11401415

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93830530T ATE142878T1 (de) 1993-01-25 1993-12-29 Verwendung der 3-indolbrenztraubensäure zur erniedrigung der glucocorticoidblutspiegel und zur vorbeugung cerebraler störungen

Country Status (7)

Country Link
US (1) US5447951A (de)
EP (1) EP0608671B1 (de)
JP (1) JP2562278B2 (de)
AT (1) ATE142878T1 (de)
DE (1) DE69304885T2 (de)
ES (1) ES2093953T3 (de)
IT (1) IT1261165B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1370268B1 (de) * 2001-03-23 2009-07-15 Corcept Therapeutics, Inc. Verfahren zur behandlung von stressbedingten erkrankungen unter verwendung von glucocorticoid-rezepto-spezifischen antagonisten
US7371763B2 (en) * 2001-04-20 2008-05-13 Bayer Pharmaceuticals Corporation Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
CN103860694A (zh) * 2014-02-14 2014-06-18 四川蜀源博业医药科技有限公司 一种鼻腔用离子敏感型原位凝胶剂及其制备方法和用途
JP7093961B2 (ja) * 2018-02-13 2022-07-01 国立大学法人金沢大学 ストレス低減薬剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1148618B (it) * 1982-10-11 1986-12-03 Polifarma Spa Procedimento enzimatico per la produzione di acido 3-indolpiruvico e utilizzazione farmaceutica di questo
IT1184282B (it) * 1985-06-28 1987-10-22 Polifarma Spa Procedimento per la produzione di alfa-chetoacidi indolici a partire da un rispettivo alfa-ammino-acido,particolarmente per produrre acido indolpiruvico
IT1206078B (it) * 1987-06-03 1989-04-14 Polifarma Spa Procedimento per la produzione di acido 3-indolpiruvico e suoi derivati loro uso farmaceutico
IT1224546B (it) * 1988-09-29 1990-10-04 Polifarma Spa Utilizzatore farmaceutica di acido 3 -indolpiruvico come agente inibitore di patologie degenerative
IT1232167B (it) * 1989-08-08 1992-01-25 Polifarma Spa Uso cosmetico di acido 3-indolpiruvico

Also Published As

Publication number Publication date
ES2093953T3 (es) 1997-01-01
EP0608671A1 (de) 1994-08-03
ITRM930034A1 (it) 1994-07-25
US5447951A (en) 1995-09-05
ITRM930034A0 (it) 1993-01-25
EP0608671B1 (de) 1996-09-18
DE69304885D1 (de) 1996-10-24
JP2562278B2 (ja) 1996-12-11
DE69304885T2 (de) 1997-03-27
JPH06234634A (ja) 1994-08-23
IT1261165B (it) 1996-05-09

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