ATE133654T1 - Neue tricyclischen steroid-analogen - Google Patents

Neue tricyclischen steroid-analogen

Info

Publication number
ATE133654T1
ATE133654T1 AT92121556T AT92121556T ATE133654T1 AT E133654 T1 ATE133654 T1 AT E133654T1 AT 92121556 T AT92121556 T AT 92121556T AT 92121556 T AT92121556 T AT 92121556T AT E133654 T1 ATE133654 T1 AT E133654T1
Authority
AT
Austria
Prior art keywords
fluoroalkyl
carbonyl
alkyl
different
same
Prior art date
Application number
AT92121556T
Other languages
English (en)
Inventor
Douglas Floyd Covey Md
Yuefei Hu
Charles Francis Zorumski Md
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Application granted granted Critical
Publication of ATE133654T1 publication Critical patent/ATE133654T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/716—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT92121556T 1991-12-20 1992-12-18 Neue tricyclischen steroid-analogen ATE133654T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/811,208 US5206415A (en) 1991-12-20 1991-12-20 Tricyclic steroid analogs

Publications (1)

Publication Number Publication Date
ATE133654T1 true ATE133654T1 (de) 1996-02-15

Family

ID=25205887

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92121556T ATE133654T1 (de) 1991-12-20 1992-12-18 Neue tricyclischen steroid-analogen

Country Status (7)

Country Link
US (3) US5206415A (de)
EP (1) EP0548824B1 (de)
JP (1) JP3238962B2 (de)
AT (1) ATE133654T1 (de)
CA (1) CA2085819A1 (de)
DE (1) DE69208068T2 (de)
DK (1) DK0548824T3 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5434274A (en) * 1991-12-20 1995-07-18 Washington University Benz(epsilon)indene compounds
US5696199A (en) * 1995-12-07 1997-12-09 Minnesota Mining And Manufacturing Company Pressure-sensitive adhesive polyacrylate polymer and method of making
US6787530B1 (en) 1996-08-23 2004-09-07 Monash University Use of pregnane-diones as analgesic agents
DE69942578D1 (de) 1998-05-22 2010-08-26 Univ R Bifunktionelle moleküle sowie darauf basierende therapien.
WO1999066915A2 (en) * 1998-06-23 1999-12-29 Southern Illinois University At Carbondale Therapeutic applications of estrogenic carboxylic acids
EP1325006A2 (de) * 2000-08-07 2003-07-09 Neurogen Corporation Heterocyclische verbindungen als liganden des gaba-a-rezeptors
US20020072509A1 (en) * 2000-10-11 2002-06-13 Stein Donald Gerald Methods for the treatment of a traumatic central nervous system injury
AR031473A1 (es) * 2000-11-20 2003-09-24 Lundbeck & Co As H Intensificadores de gaba en el tratamiento de enfermedades relacionadas con una reducida actividad neuroesteroide
US20030037354A1 (en) * 2001-08-02 2003-02-20 Ornitz David M. Animal model with disrupted Fgf14 gene
US7473687B2 (en) * 2005-03-24 2009-01-06 Emory University Methods for the treatment of a traumatic central nervous system injury
DE602006020353D1 (de) * 2005-03-24 2011-04-07 Univ Emory Progesterone Dosierungsanweisung in der Behandlung einer traumatischen Verletzung des Gehirns
EP3827747A1 (de) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharmainformatiksystem
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2830075A (en) * 1954-05-10 1958-04-08 Farinacci Nicholas Thomas 2-alpha-carbonylated 8, 13-dimethyl polyhydrophenanthrene compounds and preparation thereof
US2830325A (en) * 1956-05-10 1958-04-15 Davol Rubber Co Mold for forming open-ended bulbs
US3293284A (en) * 1964-08-07 1966-12-20 Searle & Co 1, 2-seco-alpha-nor-5 alpha-androstane-1, 2, 17 beta-triols, 17-alkylated-1, 2-seco-alpha-nor-5 alpha-androstane-1, 2, 17 beta-triols and esters thereof
US3281431A (en) * 1964-09-28 1966-10-25 Searle & Co 17-oxygenated-2-thia-5alpha-androstanes and derivatives thereof
FR1526962A (fr) * 1967-01-06 1968-05-31 Roussel Uclaf Nouveau procédé de préparation d'un composé gonatriénique et produits en résultant
IL32496A (en) * 1968-07-24 1973-06-29 Roussel Uclaf 1-oxa-a-nor-androstanes
US3821288A (en) * 1971-07-01 1974-06-28 Syntex Inc 16,17-seco-a-nor steroids
GB2068363A (en) * 1980-01-30 1981-08-12 Sarabhai Ambalal Ets Substituted Benzhydrindanes
US4874891A (en) * 1986-05-01 1989-10-17 Washington University Open "D" ring hormone analogs
AU609927B2 (en) * 1987-08-25 1991-05-09 Kelvin W. Gee Compositions and methods for alleviating stress, anxiety and seizure activity

Also Published As

Publication number Publication date
DE69208068D1 (de) 1996-03-14
EP0548824B1 (de) 1996-01-31
JP3238962B2 (ja) 2001-12-17
CA2085819A1 (en) 1993-06-21
DK0548824T3 (da) 1996-02-19
EP0548824A1 (de) 1993-06-30
DE69208068T2 (de) 1996-05-30
US5206415A (en) 1993-04-27
US5344826A (en) 1994-09-06
US5292906A (en) 1994-03-08
JPH05306257A (ja) 1993-11-19

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee