ATE130765T1 - Gentechnologisch veränderte immunglobuline. - Google Patents
Gentechnologisch veränderte immunglobuline.Info
- Publication number
- ATE130765T1 ATE130765T1 AT90904172T AT90904172T ATE130765T1 AT E130765 T1 ATE130765 T1 AT E130765T1 AT 90904172 T AT90904172 T AT 90904172T AT 90904172 T AT90904172 T AT 90904172T AT E130765 T1 ATE130765 T1 AT E130765T1
- Authority
- AT
- Austria
- Prior art keywords
- genetically modified
- modified immunoglobulins
- preparing
- found
- immunoglobulins
- Prior art date
Links
- 108060003951 Immunoglobulin Proteins 0.000 title abstract 2
- 102000018358 immunoglobulin Human genes 0.000 title abstract 2
- 229940072221 immunoglobulins Drugs 0.000 title 1
- 108010047041 Complementarity Determining Regions Proteins 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31614489A | 1989-02-24 | 1989-02-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE130765T1 true ATE130765T1 (de) | 1995-12-15 |
Family
ID=23227670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90904172T ATE130765T1 (de) | 1989-02-24 | 1990-02-23 | Gentechnologisch veränderte immunglobuline. |
Country Status (9)
Country | Link |
---|---|
US (3) | US5583202A (de) |
EP (1) | EP0460076B1 (de) |
JP (2) | JP3355351B2 (de) |
AT (1) | ATE130765T1 (de) |
CA (1) | CA2047244C (de) |
DE (2) | DE69023900D1 (de) |
DK (1) | DK0460076T3 (de) |
ES (1) | ES2082850T3 (de) |
WO (1) | WO1990009804A1 (de) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0460076B1 (de) * | 1989-02-24 | 1995-11-29 | The Regents Of The University Of California | Gentechnologisch veränderte immunglobuline |
US5969109A (en) * | 1990-02-28 | 1999-10-19 | Bona; Constantin | Chimeric antibodies comprising antigen binding sites and B and T cell epitopes |
DK96493D0 (da) * | 1993-08-26 | 1993-08-26 | Mouritsen Og Elsner Aps | Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden |
US5817308A (en) * | 1994-02-14 | 1998-10-06 | University Of Rochester | Tolerogenic fusion proteins of immunoglobulins and methods for inducing and maintaining tolerance |
US6485726B1 (en) | 1995-01-17 | 2002-11-26 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
US6030613A (en) * | 1995-01-17 | 2000-02-29 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
US6086875A (en) * | 1995-01-17 | 2000-07-11 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of immunogens |
US7361346B1 (en) * | 1996-05-15 | 2008-04-22 | Altarex Corp. | Therapeutic compositions that produce an immune response |
US20060159688A1 (en) * | 1996-05-15 | 2006-07-20 | Ragupathy Madiyalakan | Method for diagnosing efficacy of xenotypic antibody therapy |
US7318921B2 (en) * | 1996-05-15 | 2008-01-15 | Altarex Medical Corp. | Therapeutic compositions that alter the immune response |
US8038994B2 (en) * | 1996-05-15 | 2011-10-18 | Quest Pharmatech Inc. | Combination therapy for treating disease |
US20080220012A1 (en) * | 1996-05-15 | 2008-09-11 | Ragupathy Madiyalakan | Therapeutic Compositions that alter the immune response |
EP1297846A1 (de) * | 1996-05-15 | 2003-04-02 | Altarex Corporation | Verfahren und Zusammensetzung zur Rekonformierung multi-epitopischer Antigenen zur Induktion einer Immunantwort |
US6737057B1 (en) * | 1997-01-07 | 2004-05-18 | The University Of Tennessee Research Corporation | Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors |
US20020081298A1 (en) * | 1997-01-07 | 2002-06-27 | Habib Zaghouani | Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors |
JP2002507544A (ja) * | 1997-11-14 | 2002-03-12 | ユーロ−セルティーク,エス.エイ. | 抗イディオタイプ応答を引き出す能力が増強された改変型の抗体 |
CA2315944A1 (en) * | 1997-12-24 | 1999-07-08 | Diatech Pty. Ltd. | Bifunctional molecules |
US7279462B1 (en) | 1998-04-27 | 2007-10-09 | Nevagen Llc | Somatic transgene immunization and related methods |
WO2000029443A1 (en) * | 1998-11-13 | 2000-05-25 | Euro-Celtique, S.A. | Contraceptive antibody vaccines |
EP1162983A1 (de) * | 1999-02-25 | 2001-12-19 | Tai June Yoo | Impfstoff gegen hausstaub-milben antigene enthaltend nackte plasmid-dna |
WO2000064488A2 (en) * | 1999-04-27 | 2000-11-02 | Eurogen Holding, S.A. | Somatic transgene immunization and related methods |
EP1246643A4 (de) | 1999-10-14 | 2005-05-11 | Jeffery A Ledbetter | Dna impfstoffe, welcheein antigen kodieren, dass an eine cd40-bindende domäne bindet |
JP2004527449A (ja) * | 2000-02-15 | 2004-09-09 | リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | テロメラーゼ逆転写酵素を用いる癌を治療するための万能ワクチンと方法 |
MXPA02009454A (es) | 2000-03-31 | 2003-04-10 | Purdue Research Foundation | Metodo de tratamiento usando conjugados ligando-inmunogeno. |
US6801270B2 (en) * | 2000-06-26 | 2004-10-05 | Reveo, Inc. | Backlight for a liquid crystal display having high light-recycling efficiency |
GB0102145D0 (en) * | 2001-01-26 | 2001-03-14 | Scancell Ltd | Substances |
WO2002078612A2 (en) * | 2001-04-02 | 2002-10-10 | Euro-Celtique S.A. | Thrombopoietin (tpo) synthebody for stimulation of platelet production |
WO2003015716A2 (en) | 2001-08-13 | 2003-02-27 | Ige Therapeutics, Inc. | Immunoglobulin e vaccines and methods of use thereof |
KR20040053136A (ko) * | 2001-09-28 | 2004-06-23 | 펄듀 리서치 파운데이션 | 리간드-면역원 공액체를 이용한 치료 방법 |
US20070037769A1 (en) * | 2003-03-14 | 2007-02-15 | Multicell Immunotherapeutics, Inc. | Compositions and methods to treat and control tumors by loading antigen presenting cells |
EP2258712A3 (de) * | 2002-03-15 | 2011-05-04 | Multicell Immunotherapeutics, Inc. | Zusammensetzungen und Verfahren zur Einleitung bzw. Verstärkung von Antikörper- und Haupthistokompatibilität-Klasse-I- oder-Klasse-II-beschränkten T-Zell-Reaktionen unter Anwendung von Immunmodulierenden, nicht-codierenden RNA-Motiven |
US20050222060A1 (en) * | 2002-03-15 | 2005-10-06 | Bot Adrian L | Compositions and methods to initiate or enhance antibody and major-histocompatibility class I or class II-restricted t cell responses by using immunomodulatory, non-coding rna motifs |
US8603471B2 (en) | 2002-04-09 | 2013-12-10 | The Curators Of The University Of Missouri | Methods and compositions for preventing the onset of type 1 diabetes |
EP1572937B1 (de) * | 2002-04-09 | 2012-02-08 | The Scripps Research Institute | Hybrid-polypeptide mit eingefügten sequenzmotiven und ihre verwendungen |
US7744876B2 (en) | 2002-04-09 | 2010-06-29 | The Curators Of The University Of Missouri | Methods and compositions for treatment, prevention, suppression, and/or delaying the onset of type 1 diabetes |
US8603472B2 (en) | 2002-04-09 | 2013-12-10 | The Curators Of The University Of Missouri | Methods and compositions reversing pre-diabetes using fusion proteins comprising a GAD peptide |
US8609091B2 (en) | 2002-04-09 | 2013-12-17 | The Curators Of The University Of Missouri | Method for endocytic presentation of an immunosuppressive for the treatment of type 1 diabetes |
WO2003086041A2 (en) * | 2002-04-11 | 2003-10-23 | Altarex Medical Corporation | Binding agents and their use in targeting tumor cells |
AU2003224989B2 (en) * | 2002-04-19 | 2008-12-04 | Endocyte, Inc. | Adjuvant enhanced immunotherapy |
CN1795274A (zh) * | 2003-03-26 | 2006-06-28 | 多单元免疫治疗公司 | 诱导细胞死亡和/或凋亡的选定的rna基序 |
US7696322B2 (en) * | 2003-07-28 | 2010-04-13 | Catalent Pharma Solutions, Inc. | Fusion antibodies |
US20060035242A1 (en) * | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
CN101166976B (zh) * | 2005-01-13 | 2013-06-12 | 诺华疫苗和诊断公司 | 利用朊病毒特异性肽试剂的elisa试验 |
WO2006076683A2 (en) * | 2005-01-13 | 2006-07-20 | Novartis Vaccines And Diagnostics Inc. | Isolation and detection of pathogenic prions |
US20070111237A1 (en) * | 2005-09-14 | 2007-05-17 | Maurizio Zanetti | Process for identifying antigenized antibodies using ribosome cell free expression system |
US8168164B2 (en) * | 2006-02-03 | 2012-05-01 | Purdue Research Foundation | Targeted conjugates and radiation |
EP1887084A1 (de) | 2006-08-10 | 2008-02-13 | International Investment and Patents SA | Plasmide mit immunologischer Wirkung |
US8865179B2 (en) * | 2008-01-26 | 2014-10-21 | Swey-Shen Alexchen | Aptameric IgE peptides in a protein scaffold as an allergy vaccine |
AU2009243060A1 (en) * | 2008-04-30 | 2009-11-05 | Novartis Ag. | Assay for pathogenic conformers |
JP2018508481A (ja) | 2015-02-02 | 2018-03-29 | ザ ユニバーシティ オブ バーミンガム | 複数のt細胞エピトープを有する標的化部分ペプチドエピトープ複合体 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4694072A (en) * | 1982-11-30 | 1987-09-15 | Institut Pasteur | Peptides comprising an immunogenic site of poliovirus and DNAS containing nucleotide sequences coding for these peptides |
US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4631191A (en) * | 1985-06-20 | 1986-12-23 | Biotechnology Research Partners, Ltd. | Methods and compositions useful in preventing equine influenza |
GB8607679D0 (en) * | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
IL84285A (en) * | 1986-10-27 | 1993-03-15 | Int Genetic Engineering | Chimeric antibody with specificity to human tumor antigen |
EP0460076B1 (de) * | 1989-02-24 | 1995-11-29 | The Regents Of The University Of California | Gentechnologisch veränderte immunglobuline |
CA2107329C (en) * | 1991-04-18 | 1999-04-27 | Bona Constantin | Anti-human immunodeficiency virus recombinant antibodies |
-
1990
- 1990-02-23 EP EP90904172A patent/EP0460076B1/de not_active Expired - Lifetime
- 1990-02-23 ES ES90904172T patent/ES2082850T3/es not_active Expired - Lifetime
- 1990-02-23 AT AT90904172T patent/ATE130765T1/de not_active IP Right Cessation
- 1990-02-23 CA CA002047244A patent/CA2047244C/en not_active Expired - Lifetime
- 1990-02-23 DE DE69023900A patent/DE69023900D1/de not_active Expired - Fee Related
- 1990-02-23 WO PCT/US1990/001010 patent/WO1990009804A1/en active IP Right Grant
- 1990-02-23 DK DK90904172.5T patent/DK0460076T3/da active
- 1990-02-23 JP JP50442490A patent/JP3355351B2/ja not_active Expired - Fee Related
- 1990-02-23 DE DE69023900T patent/DE69023900T4/de not_active Expired - Lifetime
-
1994
- 1994-12-16 US US08/357,452 patent/US5583202A/en not_active Expired - Lifetime
- 1994-12-16 US US08/357,495 patent/US5508386A/en not_active Expired - Fee Related
-
1995
- 1995-06-06 US US08/476,914 patent/US5658762A/en not_active Expired - Lifetime
-
2000
- 2000-12-05 JP JP2000370024A patent/JP3357890B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0460076B1 (de) | 1995-11-29 |
JPH04503605A (ja) | 1992-07-02 |
ES2082850T3 (es) | 1996-04-01 |
DE69023900T2 (de) | 1996-07-04 |
JP2001190295A (ja) | 2001-07-17 |
CA2047244C (en) | 2002-09-17 |
WO1990009804A1 (en) | 1990-09-07 |
JP3357890B2 (ja) | 2002-12-16 |
DE69023900T4 (de) | 1996-10-02 |
US5508386A (en) | 1996-04-16 |
US5658762A (en) | 1997-08-19 |
US5583202A (en) | 1996-12-10 |
EP0460076A4 (en) | 1992-08-05 |
DE69023900D1 (de) | 1996-01-11 |
DK0460076T3 (da) | 1996-03-25 |
CA2047244A1 (en) | 1990-08-25 |
JP3355351B2 (ja) | 2002-12-09 |
EP0460076A1 (de) | 1991-12-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69023900D1 (de) | Gentechnologisch veränderte immunglobuline. | |
HK129394A (en) | Recombinant immunoglobulin preparations, methods for their preparation, dna sequences, expression vectors and recombinant host cells therefor | |
SE9201331D0 (sv) | Protein l och hybridproteiner daerav | |
DE3750339D1 (de) | HTLV-III umhüllende Peptiden. | |
DE69535719D1 (de) | Fas-antigenbindender ligand | |
PT96097A (pt) | Processo para a preparacao de antigene de toxoplasma gondii bem como de meios de diagnostico, vacinas e anticorpos deles derivados | |
MX24652A (es) | Compuestos de adn recombinante, vectores para la expresion de formas zimogenas de proteina c humana, celulas huesped transformadas y metodo para la prduccion recombinante de formas zimogenas de la proteina c humana. | |
NZ296564A (en) | Method of improving antigenicity of antigens or haptens, fusion with rsv peptides; vaccines, vectors, nucleotides | |
DE69029808D1 (de) | Monoklonale antikörper | |
DK1119630T3 (da) | Nukleinsyrekonstruktioner til genetisk immunisering | |
FI103730B1 (fi) | Molekyylikloonauksella aikaansaadut haiman saarekesoluantigeenit | |
SG95574A1 (en) | Immunoreactive antigens of hepatitia e virus | |
DE68907735D1 (de) | Genfragmente, die die variable region eines anti-hiv-antikoerpers codieren, von diesen exprimierte chimaere anti-hiv-antikoerper und verfahren zu deren herstellung. | |
ATE233811T1 (de) | Blutplaettchen-gpiiia p1a1 und -p1a2-epitope, ihre herstellung und verwendung | |
NO174153C (no) | Antigen og monoklonalt antistoff for anvendelse in vitro, samt immunologiske reagenser inneholdende disse | |
ATE72400T1 (de) | Kreuzreaktive und schuetzende epitope von circumsporozoit-proteinen. | |
DE3877136D1 (de) | Rekombinantes histidinreiches protein von plasmodium falciparum, seine herstellung und verwendung. | |
DE60025522D1 (de) | Mycoplasma mycoides subsp. mycoides sc antigenisches lppq protein, seine herstellung und verwendung | |
ATE125306T1 (de) | Monoklonale antikörper, die einen unterschied zwischen nativproteinen und proteinen mit einer modifizierten sequenz machen. | |
MX24651A (es) | Compuestos de adn recombinante, vectores de expresion de mutantes de glicosilacion de la proteina c humana, celulas huesped transformadas y metodo para la produccion recombinante de formas zimogenas de proteina c humana. | |
DE69931282D1 (de) | Nukleinsäure die in menschliche Tumoren vervielfältigt sind, und damit zusammenhängende Materiale und Verfahren | |
NO912192L (no) | Rekombinante dna og fremgangsmaate for fremstilling av chimere antistoffer. | |
ATE92102T1 (de) | Genfragmente, die die variable region eines anti- hiv-antikoerpers codieren, von diesen exprimierte chimaere anti-hiv-antikoerper und verfahren zu deren herstellung. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee | ||
EEWE | Authorization for restitution | ||
EEIH | Change in the person of patent owner | ||
REN | Ceased due to non-payment of the annual fee |