ATE130631T1 - Verfahren zur isolierung für thymidin-kinase der herpesvirus kodierenden dns. - Google Patents
Verfahren zur isolierung für thymidin-kinase der herpesvirus kodierenden dns.Info
- Publication number
- ATE130631T1 ATE130631T1 AT89909936T AT89909936T ATE130631T1 AT E130631 T1 ATE130631 T1 AT E130631T1 AT 89909936 T AT89909936 T AT 89909936T AT 89909936 T AT89909936 T AT 89909936T AT E130631 T1 ATE130631 T1 AT E130631T1
- Authority
- AT
- Austria
- Prior art keywords
- thymidine kinase
- herpes virus
- isolation
- methods
- dna coding
- Prior art date
Links
- 108020004440 Thymidine kinase Proteins 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 241001529453 unidentified herpesvirus Species 0.000 title abstract 3
- 102000006601 Thymidine Kinase Human genes 0.000 title abstract 2
- 238000002955 isolation Methods 0.000 title abstract 2
- IQFYYKKMVGJFEH-XLPZGREQSA-N Thymidine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 IQFYYKKMVGJFEH-XLPZGREQSA-N 0.000 abstract 6
- DWRXFEITVBNRMK-UHFFFAOYSA-N Beta-D-1-Arabinofuranosylthymine Natural products O=C1NC(=O)C(C)=CN1C1C(O)C(O)C(CO)O1 DWRXFEITVBNRMK-UHFFFAOYSA-N 0.000 abstract 3
- 241000701087 Felid alphaherpesvirus 1 Species 0.000 abstract 3
- IQFYYKKMVGJFEH-UHFFFAOYSA-N beta-L-thymidine Natural products O=C1NC(=O)C(C)=CN1C1OC(CO)C(O)C1 IQFYYKKMVGJFEH-UHFFFAOYSA-N 0.000 abstract 3
- 229940104230 thymidine Drugs 0.000 abstract 3
- 108020004414 DNA Proteins 0.000 abstract 2
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 238000003752 polymerase chain reaction Methods 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16641—Use of virus, viral particle or viral elements as a vector
- C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23015888A | 1988-08-08 | 1988-08-08 | |
| US37904189A | 1989-07-12 | 1989-07-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE130631T1 true ATE130631T1 (de) | 1995-12-15 |
Family
ID=26923980
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89909936T ATE130631T1 (de) | 1988-08-08 | 1989-08-02 | Verfahren zur isolierung für thymidin-kinase der herpesvirus kodierenden dns. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0427788B1 (de) |
| JP (1) | JP3439472B2 (de) |
| AT (1) | ATE130631T1 (de) |
| AU (1) | AU4194089A (de) |
| CA (1) | CA1340473C (de) |
| DE (1) | DE68924916T2 (de) |
| HK (1) | HK41897A (de) |
| WO (1) | WO1990001547A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6025181A (en) * | 1990-07-06 | 2000-02-15 | University Court Of The University Of Glasgow | Equine herpesvirus-4TK mutant |
| GB9014951D0 (en) * | 1990-07-06 | 1990-08-29 | Univ Glasgow | Equine herpesvirus-4 tk vaccine |
| US5538869A (en) * | 1990-12-13 | 1996-07-23 | Board Of Regents, The University Of Texas System | In-situ hybridization probes for identification and banding of specific human chromosomes and regions |
| JP2852395B2 (ja) * | 1991-11-08 | 1999-02-03 | ファルマシア・アンド・アップジョン・カンパニー | ネコ白血病ウイルスワクチン |
| WO1993010218A1 (en) | 1991-11-14 | 1993-05-27 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Vectors including foreign genes and negative selective markers |
| US5589333A (en) * | 1992-02-03 | 1996-12-31 | Thomas Jefferson University | In situ polymerase chain reaction |
| DE69332393T2 (de) * | 1992-06-26 | 2003-06-18 | Akzo Nobel N.V., Arnheim/Arnhem | Rekombinanter Katzen-Herpesvirus-Impfstoff |
| EP0662139A1 (de) * | 1992-09-21 | 1995-07-12 | Chiron Corporation | Rekombinierender retrovirus-vektor gegen felv und/oder fiv |
| US6013506A (en) * | 1995-06-05 | 2000-01-11 | Wardley; Richard C. | Feline leukemia virus vaccines |
| FR2741806B1 (fr) * | 1995-11-30 | 1998-02-20 | Rhone Merieux | Vaccin vivant recombinant a base d'herpesvirus felin de type 1, notamment contre la peritonite infectieuse feline |
| JP2002112770A (ja) * | 2000-10-05 | 2002-04-16 | Kyoritsu Seiyaku Kk | 新規組換えネコヘルペスウイルス１型およびこれを用いた多価ワクチン |
| ES2344594T3 (es) | 2001-01-31 | 2010-09-01 | Mayo Foundation For Medical Education And Research | Deteccion del virus del herpes simplex. |
| US9982313B2 (en) * | 2012-08-17 | 2018-05-29 | Roche Molecular Systems, Inc. | Compositions and methods for detection of herpes simplex virus 1 and 2 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| AU607399B2 (en) * | 1985-09-09 | 1991-03-07 | Cetus Corporation | Infectious recombinant virus vaccine for feline leukemia |
| WO1987004463A1 (en) * | 1986-01-27 | 1987-07-30 | Syntro Corporation | Attenuated herpesviruses, herpesviruses which include foreign dna encoding an amino acid sequence and vaccine containing same |
| NZ220645A (en) * | 1986-06-20 | 1989-10-27 | Merck & Co Inc | Modified varicella-zoster virus and its cultivation |
-
1989
- 1989-08-02 WO PCT/US1989/003289 patent/WO1990001547A1/en not_active Ceased
- 1989-08-02 JP JP50923289A patent/JP3439472B2/ja not_active Expired - Fee Related
- 1989-08-02 AU AU41940/89A patent/AU4194089A/en not_active Abandoned
- 1989-08-02 EP EP89909936A patent/EP0427788B1/de not_active Expired - Lifetime
- 1989-08-02 DE DE68924916T patent/DE68924916T2/de not_active Expired - Lifetime
- 1989-08-02 AT AT89909936T patent/ATE130631T1/de not_active IP Right Cessation
- 1989-08-08 CA CA000607697A patent/CA1340473C/en not_active Expired - Fee Related
-
1997
- 1997-04-03 HK HK41897A patent/HK41897A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH04500007A (ja) | 1992-01-09 |
| AU4194089A (en) | 1990-03-05 |
| WO1990001547A1 (en) | 1990-02-22 |
| JP3439472B2 (ja) | 2003-08-25 |
| CA1340473C (en) | 1999-03-30 |
| HK41897A (en) | 1997-04-11 |
| DE68924916T2 (de) | 1996-05-15 |
| EP0427788B1 (de) | 1995-11-22 |
| DE68924916D1 (de) | 1996-01-04 |
| EP0427788A1 (de) | 1991-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |