ATE130200T1 - Neue verwendung für einen monoklonalen antikörper. - Google Patents

Neue verwendung für einen monoklonalen antikörper.

Info

Publication number
ATE130200T1
ATE130200T1 AT91810128T AT91810128T ATE130200T1 AT E130200 T1 ATE130200 T1 AT E130200T1 AT 91810128 T AT91810128 T AT 91810128T AT 91810128 T AT91810128 T AT 91810128T AT E130200 T1 ATE130200 T1 AT E130200T1
Authority
AT
Austria
Prior art keywords
monoclonal antibody
new use
specificity
fragments
variants
Prior art date
Application number
AT91810128T
Other languages
English (en)
Inventor
Hans Loibner
Dierter Scholz
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of ATE130200T1 publication Critical patent/ATE130200T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3023—Lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT91810128T 1990-02-28 1991-02-26 Neue verwendung für einen monoklonalen antikörper. ATE130200T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4006308A DE4006308A1 (de) 1990-02-28 1990-02-28 Verwendung des monoklonalen antikoerpers br 55.2 gegen kleinzelliges lungenkarzinom

Publications (1)

Publication Number Publication Date
ATE130200T1 true ATE130200T1 (de) 1995-12-15

Family

ID=6401132

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91810128T ATE130200T1 (de) 1990-02-28 1991-02-26 Neue verwendung für einen monoklonalen antikörper.

Country Status (5)

Country Link
US (1) US5523085A (de)
EP (1) EP0445078B1 (de)
JP (1) JP2996526B2 (de)
AT (1) ATE130200T1 (de)
DE (2) DE4006308A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT528767E (pt) * 1991-08-21 2000-06-30 Novartis Ag Derivados de anticorpos
WO1993024647A1 (en) * 1992-05-22 1993-12-09 Sandoz Ltd. Anti-idiotypic monoclonal antibodies against the lewis y-specific monoclonal antibody br55-2 and their uses
AT413486B (de) * 2002-07-03 2006-03-15 Igeneon Krebs Immuntherapie Verwendung eines antikörpers gerichtet gegen lewis-antigene
TWI618669B (zh) * 2016-05-09 2018-03-21 力山工業股份有限公司 可收折的文具

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE468231B (sv) * 1984-05-18 1992-11-23 Kabi Pharmacia Ab Foerfarande foer att paavisa smaacelligt lungcarcinomantigen och anvaendning av antikroppar mot fukosylsialosylgangliotetraos foer framstaellning av komposition foer behandling eller in vivo/ diagnos
US4971792A (en) * 1987-03-27 1990-11-20 The Wistar Institute Monoclonal antibodies against glycolipid antigens
EP0323802A3 (de) * 1987-12-24 1989-07-26 Sandoz Ag Gegen Lungenkrebs gerichtete monoklonale Antikörper und Zelloberflächenantigen davon

Also Published As

Publication number Publication date
US5523085A (en) 1996-06-04
JPH04211612A (ja) 1992-08-03
DE4006308A1 (de) 1991-08-29
EP0445078B1 (de) 1995-11-15
DE69114546D1 (de) 1995-12-21
DE69114546T2 (de) 1996-04-04
JP2996526B2 (ja) 2000-01-11
EP0445078A1 (de) 1991-09-04

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties