ATE129155T1 - Verwendung von phosphatidylglycerol(dic 18:10) zur behandlung obstruktiver atemwegserkrankungen. - Google Patents

Verwendung von phosphatidylglycerol(dic 18:10) zur behandlung obstruktiver atemwegserkrankungen.

Info

Publication number
ATE129155T1
ATE129155T1 AT91400304T AT91400304T ATE129155T1 AT E129155 T1 ATE129155 T1 AT E129155T1 AT 91400304 T AT91400304 T AT 91400304T AT 91400304 T AT91400304 T AT 91400304T AT E129155 T1 ATE129155 T1 AT E129155T1
Authority
AT
Austria
Prior art keywords
treatment
dic
respiratory diseases
phosphatidyl glycerol
obstructive respiratory
Prior art date
Application number
AT91400304T
Other languages
English (en)
Inventor
Sophie Inserm U Girod-Vaquez
Edith Inserm U Puchelle
Claude Galabert
Jean-Marie Inserm U Zahm
Denis Inserm U Pierrot
Original Assignee
Synthelabo
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo, Inst Nat Sante Rech Med filed Critical Synthelabo
Application granted granted Critical
Publication of ATE129155T1 publication Critical patent/ATE129155T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT91400304T 1990-02-20 1991-02-08 Verwendung von phosphatidylglycerol(dic 18:10) zur behandlung obstruktiver atemwegserkrankungen. ATE129155T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909001999A FR2658418B1 (fr) 1990-02-20 1990-02-20 Compositions pharmaceutiques a base de phospholipides.

Publications (1)

Publication Number Publication Date
ATE129155T1 true ATE129155T1 (de) 1995-11-15

Family

ID=9393891

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91400304T ATE129155T1 (de) 1990-02-20 1991-02-08 Verwendung von phosphatidylglycerol(dic 18:10) zur behandlung obstruktiver atemwegserkrankungen.

Country Status (9)

Country Link
US (1) US5262405A (de)
EP (1) EP0450991B1 (de)
JP (1) JPH04211014A (de)
KR (1) KR910021246A (de)
AT (1) ATE129155T1 (de)
CA (1) CA2036629A1 (de)
DE (1) DE69113848T2 (de)
DK (1) DK0450991T3 (de)
FR (1) FR2658418B1 (de)

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Publication number Priority date Publication date Assignee Title
US5698537A (en) * 1996-06-18 1997-12-16 Clarion Pharmaceuticals Inc. Method of lowering the viscosity of mucus
CN1261791A (zh) * 1997-07-02 2000-08-02 Sdg有限公司 诊断或治疗用途的靶向脂质体构建物
IL121322A (en) * 1997-07-16 2002-07-25 Modus Biolog Membranes Ltd Modular pharmacological preparation of the immune system based on fats and its preparation
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
DE19909115A1 (de) * 1999-03-03 2000-09-07 Florian Lang Verwendung von Ceramiden zur Behandlung cystischer Fibrose
DE10012151A1 (de) 2000-03-13 2001-09-27 Gsf Forschungszentrum Umwelt Mittel zur Behandlung von Erkrankungen des Tracheo-Brochialtraktes, insbesondere der COPD
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
WO2003053411A1 (en) 2001-12-19 2003-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
US20050058698A1 (en) * 2002-01-21 2005-03-17 Nolan Yvonne Mairead Pharmaceutically acceptable phosphate-glycerol carrying bodies and uses relating to Parkinson's Disease
CA2368656A1 (en) * 2002-01-21 2003-07-21 Vasogen Ireland Limited Receptor-ligand pairing for anti-inflammatory response
WO2005007169A2 (en) * 2003-07-21 2005-01-27 Vasogen Ireland Limited Liposomes containing phosphate glycerol groups for treating acute inflammatory condition
GB0322448D0 (en) * 2003-09-25 2003-10-29 Lamellar Therapeutics Ltd Using lamellar bodies to modify linear biological macro molecules
JP2007537833A (ja) * 2004-05-20 2007-12-27 ディスカバリー ラボラトリーズ，インコーポレイテッド 非侵襲的な肺吸入のための方法、システム、及び装置
US8028697B2 (en) 2005-04-28 2011-10-04 Trudell Medical International Ventilator circuit and method for the use thereof
US8563683B2 (en) 2006-07-20 2013-10-22 University Of Rochester Synthetic lung surfactant and use thereof
EP2265309B1 (de) * 2008-03-17 2015-12-16 Discovery Laboratories, Inc. Luftkreislaufadapter und proximales aerosolfreisetzungssystem
CA2683353C (en) 2008-10-22 2015-12-15 Trudell Medical International Modular aerosol delivery system
US9585930B2 (en) * 2011-03-20 2017-03-07 Trustees Of Boston University Therapeutic agent for emphysema and COPD
US12364661B2 (en) * 2015-11-20 2025-07-22 The Regents Of The University Of California Deformable nano-scale vehicles (DNVS) for trans-blood brain barrier, trans-mucosal, and transdermal drug delivery
US12329759B2 (en) 2019-10-17 2025-06-17 Trustees Of Boston University Methods and compositions relating to lung function

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2343481A1 (fr) * 1976-03-11 1977-10-07 Gerlich Norbert Composition destinee a empecher les lesions des membranes biologiques et a regenerer ces membranes une fois qu'elles ont ete endommagees
GB2045612B (en) * 1979-03-27 1983-04-20 Nippon Shoji Kaisha Ltd Pharmaceutical compositions containing phosphatidic acids for the treatment of disorders of consciousness perception and movement
US4725588A (en) * 1979-11-07 1988-02-16 The United States Of America As Represented By The United States Department Of Energy Alkyl phospholipid antihypertensive agents in method of lowering blood pressure
US4666893A (en) * 1983-02-15 1987-05-19 St. Thomas Institute Methods of inducing resistance to bacterial and viral infections
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
IL71051A (en) * 1984-02-23 1988-02-29 Yeda Res & Dev Compositions containing active lipids for the treatment of cystic fibrosis
FR2586587B1 (fr) * 1985-08-30 1987-10-23 Adir Nouveaux surfactants artificiels, leur preparation et les compositions pharmaceutiques qui les contiennent.
GB8522964D0 (en) * 1985-09-17 1985-10-23 Biocompatibles Ltd Aerosol
US5032585A (en) * 1987-02-17 1991-07-16 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy
IT1212137B (it) * 1987-04-08 1989-11-08 Rosanna Lodi Composizioni farmaceutiche per il trattamento di sindromi psico-organiche cerebrali.
US4997761A (en) * 1987-10-06 1991-03-05 Houston Biotechnology Incorporated Phosphatidyl treatment of viral disease
AU2823489A (en) * 1987-12-09 1989-07-05 Regents Of The University Of California, The Liposome-encapsulated anti-viral composition and method
CA2037478A1 (en) * 1990-03-05 1991-09-06 Richard Gregory Diagnostic and treatment methods involving the cystic fibrosis transmembrane regulator

Also Published As

Publication number Publication date
EP0450991A2 (de) 1991-10-09
KR910021246A (ko) 1991-12-20
CA2036629A1 (fr) 1991-08-21
FR2658418B1 (fr) 1994-09-02
DE69113848T2 (de) 1996-04-25
DK0450991T3 (da) 1996-03-04
FR2658418A1 (fr) 1991-08-23
JPH04211014A (ja) 1992-08-03
US5262405A (en) 1993-11-16
EP0450991A3 (en) 1992-12-16
EP0450991B1 (de) 1995-10-18
DE69113848D1 (de) 1995-11-23

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee