ATE129155T1 - Verwendung von phosphatidylglycerol(dic 18:10) zur behandlung obstruktiver atemwegserkrankungen. - Google Patents

Verwendung von phosphatidylglycerol(dic 18:10) zur behandlung obstruktiver atemwegserkrankungen.

Info

Publication number
ATE129155T1
ATE129155T1 AT91400304T AT91400304T ATE129155T1 AT E129155 T1 ATE129155 T1 AT E129155T1 AT 91400304 T AT91400304 T AT 91400304T AT 91400304 T AT91400304 T AT 91400304T AT E129155 T1 ATE129155 T1 AT E129155T1
Authority
AT
Austria
Prior art keywords
treatment
dic
respiratory diseases
phosphatidyl glycerol
obstructive respiratory
Prior art date
Application number
AT91400304T
Other languages
English (en)
Inventor
Sophie Inserm U Girod-Vaquez
Edith Inserm U Puchelle
Claude Galabert
Jean-Marie Inserm U Zahm
Denis Inserm U Pierrot
Original Assignee
Synthelabo
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo, Inst Nat Sante Rech Med filed Critical Synthelabo
Application granted granted Critical
Publication of ATE129155T1 publication Critical patent/ATE129155T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT91400304T 1990-02-20 1991-02-08 Verwendung von phosphatidylglycerol(dic 18:10) zur behandlung obstruktiver atemwegserkrankungen. ATE129155T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR909001999A FR2658418B1 (fr) 1990-02-20 1990-02-20 Compositions pharmaceutiques a base de phospholipides.

Publications (1)

Publication Number Publication Date
ATE129155T1 true ATE129155T1 (de) 1995-11-15

Family

ID=9393891

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91400304T ATE129155T1 (de) 1990-02-20 1991-02-08 Verwendung von phosphatidylglycerol(dic 18:10) zur behandlung obstruktiver atemwegserkrankungen.

Country Status (9)

Country Link
US (1) US5262405A (de)
EP (1) EP0450991B1 (de)
JP (1) JPH04211014A (de)
KR (1) KR910021246A (de)
AT (1) ATE129155T1 (de)
CA (1) CA2036629A1 (de)
DE (1) DE69113848T2 (de)
DK (1) DK0450991T3 (de)
FR (1) FR2658418B1 (de)

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US5698537A (en) * 1996-06-18 1997-12-16 Clarion Pharmaceuticals Inc. Method of lowering the viscosity of mucus
US6063400A (en) * 1997-07-02 2000-05-16 Sdg, Inc. Targeted liposomal constructs for diagnostic and therapeutic uses
IL121322A (en) * 1997-07-16 2002-07-25 Modus Biolog Membranes Ltd Modular pharmacological preparation of the immune system based on fats and its preparation
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
DE19909115A1 (de) * 1999-03-03 2000-09-07 Florian Lang Verwendung von Ceramiden zur Behandlung cystischer Fibrose
DE10012151A1 (de) * 2000-03-13 2001-09-27 Gsf Forschungszentrum Umwelt Mittel zur Behandlung von Erkrankungen des Tracheo-Brochialtraktes, insbesondere der COPD
US7442388B2 (en) 2000-05-10 2008-10-28 Weers Jeffry G Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
CA2468958C (en) 2001-12-19 2012-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
CA2368656A1 (en) * 2002-01-21 2003-07-21 Vasogen Ireland Limited Receptor-ligand pairing for anti-inflammatory response
US20050058698A1 (en) * 2002-01-21 2005-03-17 Nolan Yvonne Mairead Pharmaceutically acceptable phosphate-glycerol carrying bodies and uses relating to Parkinson's Disease
EA200600297A1 (ru) * 2003-07-21 2006-08-25 Васоджен Айеленд Лимитед Лечение острого воспалительного состояния
GB0322448D0 (en) * 2003-09-25 2003-10-29 Lamellar Therapeutics Ltd Using lamellar bodies to modify linear biological macro molecules
CA2567334A1 (en) * 2004-05-20 2005-12-08 Discovery Laboratories, Inc. Methods , systems and devices for noninvasive pulmonary delivery
US8028697B2 (en) 2005-04-28 2011-10-04 Trudell Medical International Ventilator circuit and method for the use thereof
US8563683B2 (en) 2006-07-20 2013-10-22 University Of Rochester Synthetic lung surfactant and use thereof
JP5507539B2 (ja) 2008-03-17 2014-05-28 ディスカバリー ラボラトリーズ、インク. 換気回路アダプターおよび近位エアロゾル送達システム
ES2402241T3 (es) 2008-10-22 2013-04-30 Trudell Medical International Sistema de suministro de aerosol modular
WO2012129237A2 (en) * 2011-03-20 2012-09-27 Trustees Of Boston University Therapeutic agent for emphysema and copd

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2343481A1 (fr) * 1976-03-11 1977-10-07 Gerlich Norbert Composition destinee a empecher les lesions des membranes biologiques et a regenerer ces membranes une fois qu'elles ont ete endommagees
GB2045612B (en) * 1979-03-27 1983-04-20 Nippon Shoji Kaisha Ltd Pharmaceutical compositions containing phosphatidic acids for the treatment of disorders of consciousness perception and movement
US4725588A (en) * 1979-11-07 1988-02-16 The United States Of America As Represented By The United States Department Of Energy Alkyl phospholipid antihypertensive agents in method of lowering blood pressure
US4666893A (en) * 1983-02-15 1987-05-19 St. Thomas Institute Methods of inducing resistance to bacterial and viral infections
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
IL71051A (en) * 1984-02-23 1988-02-29 Yeda Res & Dev Compositions containing active lipids for the treatment of cystic fibrosis
FR2586587B1 (fr) * 1985-08-30 1987-10-23 Adir Nouveaux surfactants artificiels, leur preparation et les compositions pharmaceutiques qui les contiennent.
GB8522964D0 (en) * 1985-09-17 1985-10-23 Biocompatibles Ltd Aerosol
JPS62152531A (ja) * 1985-12-26 1987-07-07 Dai Ichi Seiyaku Co Ltd リポソ−ムの製造法
US5032585A (en) * 1987-02-17 1991-07-16 Board Of Regents, The University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for surfactant replacement therapy
IT1212137B (it) * 1987-04-08 1989-11-08 Rosanna Lodi Composizioni farmaceutiche per il trattamento di sindromi psico-organiche cerebrali.
US4997761A (en) * 1987-10-06 1991-03-05 Houston Biotechnology Incorporated Phosphatidyl treatment of viral disease
AU2823489A (en) * 1987-12-09 1989-07-05 Regents Of The University Of California, The Liposome-encapsulated anti-viral composition and method
CA2037478A1 (en) * 1990-03-05 1991-09-06 Richard Gregory Diagnostic and treatment methods involving the cystic fibrosis transmembrane regulator

Also Published As

Publication number Publication date
FR2658418B1 (fr) 1994-09-02
CA2036629A1 (fr) 1991-08-21
FR2658418A1 (fr) 1991-08-23
EP0450991A3 (en) 1992-12-16
DE69113848D1 (de) 1995-11-23
JPH04211014A (ja) 1992-08-03
KR910021246A (ko) 1991-12-20
US5262405A (en) 1993-11-16
EP0450991A2 (de) 1991-10-09
DK0450991T3 (da) 1996-03-04
EP0450991B1 (de) 1995-10-18
DE69113848T2 (de) 1996-04-25

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee