ATE127685T1 - Verzögerte arzneistoffabgabe durch topische anwendung bioadhäsiver liposomen. - Google Patents

Verzögerte arzneistoffabgabe durch topische anwendung bioadhäsiver liposomen.

Info

Publication number
ATE127685T1
ATE127685T1 AT92906507T AT92906507T ATE127685T1 AT E127685 T1 ATE127685 T1 AT E127685T1 AT 92906507 T AT92906507 T AT 92906507T AT 92906507 T AT92906507 T AT 92906507T AT E127685 T1 ATE127685 T1 AT E127685T1
Authority
AT
Austria
Prior art keywords
liposomes
bioadhesiv
drug release
topical application
delayed drug
Prior art date
Application number
AT92906507T
Other languages
English (en)
Inventor
Rimona Margalit
Original Assignee
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int filed Critical Baxter Int
Application granted granted Critical
Publication of ATE127685T1 publication Critical patent/ATE127685T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C233/07—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT92906507T 1991-02-14 1991-10-30 Verzögerte arzneistoffabgabe durch topische anwendung bioadhäsiver liposomen. ATE127685T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65587991A 1991-02-14 1991-02-14

Publications (1)

Publication Number Publication Date
ATE127685T1 true ATE127685T1 (de) 1995-09-15

Family

ID=24630764

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92906507T ATE127685T1 (de) 1991-02-14 1991-10-30 Verzögerte arzneistoffabgabe durch topische anwendung bioadhäsiver liposomen.

Country Status (9)

Country Link
EP (1) EP0525167B1 (de)
JP (1) JP3321622B2 (de)
AT (1) ATE127685T1 (de)
AU (1) AU1367792A (de)
CA (1) CA2079447C (de)
DE (1) DE69113036T2 (de)
DK (1) DK0525167T3 (de)
ES (1) ES2079860T3 (de)
WO (1) WO1992014445A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU656173B2 (en) * 1991-02-14 1995-01-27 Baxter International Inc. Interaction between bioadhesive liposomes and target sites
GB9208339D0 (en) * 1992-04-15 1992-06-03 Unilever Plc Treatment composition
CA2140053C (en) * 1994-02-09 2000-04-04 Joel S. Rosenblatt Collagen-based injectable drug delivery system and its use
US5658588A (en) * 1995-03-31 1997-08-19 University Of Cincinnati Fibrinogen-coated liposomes
US6096863A (en) * 1996-08-23 2000-08-01 Regents Of The University Of Minnesota Self-assembling amphiphiles for construction of peptide secondary structures
EP0963196B1 (de) * 1996-09-27 2005-01-19 Jagotec Ag Arzneistoffverabreichungssystem mit hyaluronsäure
US20030180348A1 (en) * 2002-03-22 2003-09-25 Levinson R. Saul Transcellular drug delivery system
EP1829526B1 (de) 2004-11-02 2016-01-20 National University Corporation Tokyo Medical and Dental University Liposom und verfahren zur injektion einer substanz in eine zelle unter verwendung des liposoms
EP1853303B1 (de) * 2005-02-14 2015-12-02 DPM Therapeutics Corporation Stabilisierte zusammensetzungen zur topischen verabreichung und herstellungsverfahren dafür
US7838011B2 (en) 2005-02-14 2010-11-23 Pankaj Modi Stabilized protein compositions for topical administration and methods of making same
US7727537B2 (en) 2005-02-14 2010-06-01 Dpm Therapeutics Corp. Stabilized compositions for topical administration and methods of making same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5064655A (en) * 1989-02-24 1991-11-12 Liposome Technology, Inc. Liposome gel composition and method

Also Published As

Publication number Publication date
AU1367792A (en) 1992-09-15
JPH05506253A (ja) 1993-09-16
ES2079860T3 (es) 1996-01-16
EP0525167A1 (de) 1993-02-03
DE69113036D1 (de) 1995-10-19
CA2079447A1 (en) 1992-08-15
CA2079447C (en) 2004-02-10
EP0525167B1 (de) 1995-09-13
JP3321622B2 (ja) 2002-09-03
WO1992014445A1 (en) 1992-09-03
DK0525167T3 (da) 1995-11-13
DE69113036T2 (de) 1996-05-02

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee