ATE127685T1 - Verzögerte arzneistoffabgabe durch topische anwendung bioadhäsiver liposomen. - Google Patents
Verzögerte arzneistoffabgabe durch topische anwendung bioadhäsiver liposomen.Info
- Publication number
- ATE127685T1 ATE127685T1 AT92906507T AT92906507T ATE127685T1 AT E127685 T1 ATE127685 T1 AT E127685T1 AT 92906507 T AT92906507 T AT 92906507T AT 92906507 T AT92906507 T AT 92906507T AT E127685 T1 ATE127685 T1 AT E127685T1
- Authority
- AT
- Austria
- Prior art keywords
- liposomes
- bioadhesiv
- drug release
- topical application
- delayed drug
- Prior art date
Links
- 239000002502 liposome Substances 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 230000000699 topical effect Effects 0.000 title abstract 2
- 230000003111 delayed effect Effects 0.000 title 1
- 239000000227 bioadhesive Substances 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 230000007246 mechanism Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/04—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C233/07—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65587991A | 1991-02-14 | 1991-02-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE127685T1 true ATE127685T1 (de) | 1995-09-15 |
Family
ID=24630764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92906507T ATE127685T1 (de) | 1991-02-14 | 1991-10-30 | Verzögerte arzneistoffabgabe durch topische anwendung bioadhäsiver liposomen. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0525167B1 (de) |
| JP (1) | JP3321622B2 (de) |
| AT (1) | ATE127685T1 (de) |
| AU (1) | AU1367792A (de) |
| CA (1) | CA2079447C (de) |
| DE (1) | DE69113036T2 (de) |
| DK (1) | DK0525167T3 (de) |
| ES (1) | ES2079860T3 (de) |
| WO (1) | WO1992014445A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2079450A1 (en) * | 1991-02-14 | 1992-08-15 | Rimona Margalit | Interaction between bioadhesive liposomes and target sites |
| GB9208339D0 (en) * | 1992-04-15 | 1992-06-03 | Unilever Plc | Treatment composition |
| CA2140053C (en) * | 1994-02-09 | 2000-04-04 | Joel S. Rosenblatt | Collagen-based injectable drug delivery system and its use |
| US5658588A (en) * | 1995-03-31 | 1997-08-19 | University Of Cincinnati | Fibrinogen-coated liposomes |
| US6096863A (en) * | 1996-08-23 | 2000-08-01 | Regents Of The University Of Minnesota | Self-assembling amphiphiles for construction of peptide secondary structures |
| DE69732308T2 (de) * | 1996-09-27 | 2005-06-02 | Jagotec Ag | Arzneistoffverabreichungssystem mit hyaluronsäure |
| US20030180348A1 (en) * | 2002-03-22 | 2003-09-25 | Levinson R. Saul | Transcellular drug delivery system |
| JP5057362B2 (ja) * | 2004-11-02 | 2012-10-24 | 国立大学法人 東京医科歯科大学 | リポソーム及びこれを用いた細胞に対する物質注入方法 |
| US7838011B2 (en) | 2005-02-14 | 2010-11-23 | Pankaj Modi | Stabilized protein compositions for topical administration and methods of making same |
| US7727537B2 (en) | 2005-02-14 | 2010-06-01 | Dpm Therapeutics Corp. | Stabilized compositions for topical administration and methods of making same |
| EP1853303B1 (de) * | 2005-02-14 | 2015-12-02 | DPM Therapeutics Corporation | Stabilisierte zusammensetzungen zur topischen verabreichung und herstellungsverfahren dafür |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0366770B1 (de) | 1988-05-16 | 1994-02-09 | Vestar, Inc. | An hormone gekoppelte liposome |
| US5064655A (en) * | 1989-02-24 | 1991-11-12 | Liposome Technology, Inc. | Liposome gel composition and method |
| FR2645741B1 (fr) | 1989-03-20 | 1995-06-23 | Dior Christian Parfums | Procede pour fixer un produit sur la membrane d'un keratinocyte au moyen d'une liaison ligand-recepteur, procede de preparation d'un tel produit, produit obtenu, composition cosmetique ou pharmaceutique le contenant et son procede de preparation |
-
1991
- 1991-10-30 WO PCT/US1991/008111 patent/WO1992014445A1/en not_active Ceased
- 1991-10-30 ES ES92906507T patent/ES2079860T3/es not_active Expired - Lifetime
- 1991-10-30 AU AU13677/92A patent/AU1367792A/en not_active Withdrawn
- 1991-10-30 JP JP50585292A patent/JP3321622B2/ja not_active Expired - Fee Related
- 1991-10-30 EP EP92906507A patent/EP0525167B1/de not_active Expired - Lifetime
- 1991-10-30 AT AT92906507T patent/ATE127685T1/de not_active IP Right Cessation
- 1991-10-30 DE DE69113036T patent/DE69113036T2/de not_active Expired - Fee Related
- 1991-10-30 DK DK92906507.6T patent/DK0525167T3/da active
- 1991-10-30 CA CA002079447A patent/CA2079447C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH05506253A (ja) | 1993-09-16 |
| WO1992014445A1 (en) | 1992-09-03 |
| JP3321622B2 (ja) | 2002-09-03 |
| CA2079447C (en) | 2004-02-10 |
| DK0525167T3 (da) | 1995-11-13 |
| ES2079860T3 (es) | 1996-01-16 |
| DE69113036T2 (de) | 1996-05-02 |
| EP0525167B1 (de) | 1995-09-13 |
| CA2079447A1 (en) | 1992-08-15 |
| DE69113036D1 (de) | 1995-10-19 |
| AU1367792A (en) | 1992-09-15 |
| EP0525167A1 (de) | 1993-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |