ATE125264T1 - Lösungsmittelfreies verfahren zur herstellung von 1,2:5,6-di-o-isopropylidene-3-o-3'-(n',n'- dimethylamino-n- propyl)-alpha,d-glucofuranose und 1,2:5,6-di-o-isopropylidene- 3-o-heptyl- alpha, d-glucofuranose und selektive hydrolyse davon. - Google Patents

Lösungsmittelfreies verfahren zur herstellung von 1,2:5,6-di-o-isopropylidene-3-o-3'-(n',n'- dimethylamino-n- propyl)-alpha,d-glucofuranose und 1,2:5,6-di-o-isopropylidene- 3-o-heptyl- alpha, d-glucofuranose und selektive hydrolyse davon.

Info

Publication number
ATE125264T1
ATE125264T1 AT92907010T AT92907010T ATE125264T1 AT E125264 T1 ATE125264 T1 AT E125264T1 AT 92907010 T AT92907010 T AT 92907010T AT 92907010 T AT92907010 T AT 92907010T AT E125264 T1 ATE125264 T1 AT E125264T1
Authority
AT
Austria
Prior art keywords
glucofuranose
isopropylidene
alpha
substituted
mixture
Prior art date
Application number
AT92907010T
Other languages
English (en)
Inventor
Sudershan K Arora
Original Assignee
Greenwich Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Greenwich Pharma filed Critical Greenwich Pharma
Application granted granted Critical
Publication of ATE125264T1 publication Critical patent/ATE125264T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Protection Of Plants (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT92907010T 1991-02-20 1992-02-07 Lösungsmittelfreies verfahren zur herstellung von 1,2:5,6-di-o-isopropylidene-3-o-3'-(n',n'- dimethylamino-n- propyl)-alpha,d-glucofuranose und 1,2:5,6-di-o-isopropylidene- 3-o-heptyl- alpha, d-glucofuranose und selektive hydrolyse davon. ATE125264T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65831191A 1991-02-20 1991-02-20

Publications (1)

Publication Number Publication Date
ATE125264T1 true ATE125264T1 (de) 1995-08-15

Family

ID=24640726

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92907010T ATE125264T1 (de) 1991-02-20 1992-02-07 Lösungsmittelfreies verfahren zur herstellung von 1,2:5,6-di-o-isopropylidene-3-o-3'-(n',n'- dimethylamino-n- propyl)-alpha,d-glucofuranose und 1,2:5,6-di-o-isopropylidene- 3-o-heptyl- alpha, d-glucofuranose und selektive hydrolyse davon.

Country Status (17)

Country Link
US (1) US5344924A (de)
EP (2) EP0572521B1 (de)
JP (1) JP3170280B2 (de)
KR (1) KR100211750B1 (de)
CN (1) CN1034866C (de)
AT (1) ATE125264T1 (de)
AU (1) AU659446B2 (de)
CA (1) CA2104476A1 (de)
DE (1) DE69203597T2 (de)
DK (1) DK0572521T3 (de)
ES (1) ES2078739T3 (de)
FI (1) FI105553B (de)
GR (1) GR3017070T3 (de)
IE (1) IE920527A1 (de)
IL (1) IL100833A0 (de)
NO (1) NO300638B1 (de)
WO (1) WO1992014745A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5360792A (en) * 1991-12-20 1994-11-01 Greenwich Pharmaceuticals Incorporated Anti-proliferative and anti-inflammatory compounds: 5- or 6-deoxy hexose monosaccharides having a saturated nitrogen-containing heterocycle at the 5- or 6-position bound through the nitrogen atom
US5432163A (en) * 1992-11-13 1995-07-11 Greenwich Pharmaceuticals Incorporated Anti-proliferative and anti-inflammatory compounds: derivatives of pentose monosaccharides
AU7101994A (en) * 1993-06-11 1995-01-03 Boston Life Sciences, Inc. Immunomodulatory, anti-inflammatory, and anti-proliferative compounds: 5,6-dideoxy, 5-amino derivatives of idose and 6-deoxy, 6-amino derivatives of glucose
ATE381932T1 (de) * 1996-06-18 2008-01-15 Kyowa Hakko Kogyo Kk Liposomale zubereitungen von indolocarbazol- derivaten
US6329344B1 (en) * 1998-10-22 2001-12-11 Ranbaxy Laboratories Limited Derivatives of monosaccharides as cell adhesion inhibitors
US7985856B2 (en) * 2007-10-18 2011-07-26 National Tsing Hua University Method for preparing hexose derivatives

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1488355A (en) * 1921-04-25 1924-03-25 Lilienfeld Leon Production of ethers of carbohydrates having the empirical formula n(c6h10o5), their conversion products and derivatives
US2715121A (en) * 1950-09-09 1955-08-09 American Home Prod Alkyl sugar derivatives and their preparation
US3939145A (en) * 1973-03-01 1976-02-17 Strategic Medical Research Corporation Novel ethereally monosubstituted monosaccharides
US3965262A (en) * 1973-03-01 1976-06-22 Strategic Medical Research Corporation Method of enhancing learning and/or memory in warm blooded animals
US3939146A (en) * 1973-03-01 1976-02-17 Strategic Medical Research Corporation Novel ethereal monosubstitutions of monosaccharide derivatives
USRE30379E (en) * 1973-03-01 1980-08-19 Strategic Medical Research Corp. Ethereal monosubstitutions of monosaccharide derivatives
US4016261A (en) * 1973-03-01 1977-04-05 Strategic Medical Research Corporation Therapeutic composition and method of therapeutically treating warm blooded animals therewith
USRE32268E (en) * 1973-03-01 1986-10-21 Strategic Medical Research Corp. Therapeutic composition and method of therapeutically treating warm blooded animals therewith
US4017608A (en) * 1973-12-14 1977-04-12 Strategic Medical Research Corporation Therapeutic composition and method of therapeutically treating warm blooded animals therewith
US4056322A (en) * 1973-12-14 1977-11-01 Strategic Medical Research Corporation Preparation of ethers of monosaccharides
GB1589916A (en) * 1976-11-16 1981-05-20 Prodotti Antibiotici Spa Glucofuranose derivatives
USRE30354E (en) * 1978-02-17 1980-07-29 Strategic Medical Research Corp. Novel ethereally monosubstituted monosaccharides
US4735934A (en) * 1981-02-17 1988-04-05 Greenwich Pharmaceuticals Incorporated Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease
US4738953A (en) * 1981-02-17 1988-04-19 Greenwich Pharmaceuticals Incorporated Method of therapeutically treating a warm blooded animal afflicted with an autoimmune disease and a synergistic composition therefor
US4996195A (en) * 1989-01-09 1991-02-26 Greenwich Pharmaceuticals Inc. Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives
US5010058A (en) * 1989-06-22 1991-04-23 501 Greenwich Pharmaceuticals Incorporated 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives

Also Published As

Publication number Publication date
NO932958L (no) 1993-08-19
JP3170280B2 (ja) 2001-05-28
AU1426492A (en) 1992-09-15
ES2078739T3 (es) 1995-12-16
IL100833A0 (en) 1992-09-06
NO932958D0 (no) 1993-08-19
CN1034866C (zh) 1997-05-14
WO1992014745A1 (en) 1992-09-03
GR3017070T3 (en) 1995-11-30
CA2104476A1 (en) 1992-08-21
JPH06508107A (ja) 1994-09-14
DE69203597T2 (de) 1996-01-04
FI105553B (fi) 2000-09-15
DE69203597D1 (de) 1995-08-24
KR100211750B1 (ko) 1999-08-02
AU659446B2 (en) 1995-05-18
EP0572521B1 (de) 1995-07-19
EP0499904A1 (de) 1992-08-26
EP0572521A1 (de) 1993-12-08
DK0572521T3 (da) 1995-10-02
FI933653A0 (fi) 1993-08-19
CN1065068A (zh) 1992-10-07
US5344924A (en) 1994-09-06
FI933653A (fi) 1993-08-19
NO300638B1 (no) 1997-06-30
IE920527A1 (en) 1992-08-26

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EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee