ATE123224T1 - Molekulare köder und deren verwendung. - Google Patents
Molekulare köder und deren verwendung.Info
- Publication number
- ATE123224T1 ATE123224T1 AT88908569T AT88908569T ATE123224T1 AT E123224 T1 ATE123224 T1 AT E123224T1 AT 88908569 T AT88908569 T AT 88908569T AT 88908569 T AT88908569 T AT 88908569T AT E123224 T1 ATE123224 T1 AT E123224T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor
- pct
- decoyant
- retains
- sec
- Prior art date
Links
- 102000005962 receptors Human genes 0.000 abstract 5
- 108020003175 receptors Proteins 0.000 abstract 5
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 108010041397 CD4 Antigens Proteins 0.000 abstract 1
- 108010009685 Cholinergic Receptors Proteins 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 241000251733 Tetronarce californica Species 0.000 abstract 1
- 102000034337 acetylcholine receptors Human genes 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000001851 biosynthetic effect Effects 0.000 abstract 1
- 230000002156 curarimimetic effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000002581 neurotoxin Substances 0.000 abstract 1
- 231100000618 neurotoxin Toxicity 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70514—CD4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Polyamides (AREA)
- Developing Agents For Electrophotography (AREA)
- Paper (AREA)
- Battery Electrode And Active Subsutance (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL8368787A IL83687A (en) | 1987-08-30 | 1987-08-30 | Pharmaceutical compositions comprising molecular decays and their use in the manufacture of said compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE123224T1 true ATE123224T1 (de) | 1995-06-15 |
Family
ID=11058121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88908569T ATE123224T1 (de) | 1987-08-30 | 1988-08-30 | Molekulare köder und deren verwendung. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5770572A (https=) |
| EP (1) | EP0329778B1 (https=) |
| JP (1) | JP2791074B2 (https=) |
| AT (1) | ATE123224T1 (https=) |
| AU (1) | AU2383988A (https=) |
| CA (1) | CA1336489C (https=) |
| DE (1) | DE3853910T2 (https=) |
| DK (1) | DK175596B1 (https=) |
| FI (1) | FI100169B (https=) |
| IL (1) | IL83687A (https=) |
| NO (1) | NO891787L (https=) |
| WO (1) | WO1989001779A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02501192A (ja) * | 1987-09-04 | 1990-04-26 | バイオジェン インコーポレイテッド | 可溶性t4蛋白を製造するためのdna配列、組換dna分子および方法 |
| US5132402A (en) * | 1987-11-25 | 1992-07-21 | Agency Of Industrial Science And Technology | Adsorbent, method for production thereof, and method for use thereof |
| EP0318240A3 (en) * | 1987-11-25 | 1990-08-16 | AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MINISTRY OF INTERNATIONAL TRADE & INDUSTRY | Peptide, adsorbent, method for production thereof, and method for use thereof |
| US6919076B1 (en) * | 1998-01-20 | 2005-07-19 | Pericor Science, Inc. | Conjugates of agents and transglutaminase substrate linking molecules |
| US7311920B1 (en) | 1999-10-08 | 2007-12-25 | University Of Maryland Biotechnology Institute | Virus coat protein/receptor chimeras and methods of use |
| US6908612B2 (en) | 1999-10-08 | 2005-06-21 | University Of Maryland Biotechnology Institute | Virus coat protein/receptor chimeras and methods of use |
| ITRM20010563A1 (it) * | 2001-09-14 | 2003-03-14 | Univ Siena | Peptidi antigenici multipli come antidoti nell'intossicazione da veleno di serpente. |
| US8535672B2 (en) * | 2002-04-04 | 2013-09-17 | Yissum Research Development Of The Hebrew University Of Jerusalem | Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between CD28 and the superantigen and uses thereof |
| RU2005102604A (ru) * | 2002-07-03 | 2005-09-10 | Перикор Сайенс, Инк. (Us) | Композиция гиалуроновой кислоты и способы применения |
| JP4495776B1 (ja) * | 2009-07-30 | 2010-07-07 | 日本製薬株式会社 | 融合蛋白質 |
| AU2011230619C1 (en) | 2010-03-25 | 2016-06-23 | Oregon Health & Science University | CMV glycoproteins and recombinant vectors |
| HUE037408T2 (hu) | 2011-06-10 | 2018-08-28 | Univ Oregon Health & Science | CMV glikoproteinek és rekombináns vektorok |
| CA2789539A1 (en) | 2011-09-12 | 2013-03-12 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
| US9402894B2 (en) | 2011-10-27 | 2016-08-02 | International Aids Vaccine Initiative | Viral particles derived from an enveloped virus |
| ES2631608T3 (es) | 2012-06-27 | 2017-09-01 | International Aids Vaccine Initiative | Variante de la glicoproteína Env del VIH-1 |
| EP2848937A1 (en) | 2013-09-05 | 2015-03-18 | International Aids Vaccine Initiative | Methods of identifying novel HIV-1 immunogens |
| US10058604B2 (en) | 2013-10-07 | 2018-08-28 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| WO2015153647A1 (en) * | 2014-03-31 | 2015-10-08 | Mice With Horns, Llc | Method of preventing or reducing virus transmission in animals |
| EP3069730A3 (en) | 2015-03-20 | 2017-03-15 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| US9931394B2 (en) | 2015-03-23 | 2018-04-03 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2570278B1 (fr) * | 1984-09-14 | 1987-02-13 | Pasteur Institut | Compositions et procede pour proteger les lymphocytes t contre l'agent etiologique des lymphadenopathies et du syndrome d'immunodepression acquise |
| US4761371A (en) * | 1985-02-12 | 1988-08-02 | Genentech, Inc. | Insulin receptor |
| US5126433A (en) * | 1986-08-21 | 1992-06-30 | The Trustees Of Columbia University In The City Of New York | Soluble forms of the t cell surface protein cd4 |
| DE3751751T2 (de) * | 1986-08-21 | 1996-10-17 | Univ Columbia | Für das t-zell oberflächenprotein t4 kodierende dna und verwendung von t4-fragmenten bei der behandlung von aids |
-
1987
- 1987-08-30 IL IL8368787A patent/IL83687A/en not_active IP Right Cessation
-
1988
- 1988-08-30 DE DE3853910T patent/DE3853910T2/de not_active Expired - Fee Related
- 1988-08-30 EP EP88908569A patent/EP0329778B1/en not_active Expired - Lifetime
- 1988-08-30 AU AU23839/88A patent/AU2383988A/en not_active Abandoned
- 1988-08-30 AT AT88908569T patent/ATE123224T1/de not_active IP Right Cessation
- 1988-08-30 US US07/410,778 patent/US5770572A/en not_active Expired - Lifetime
- 1988-08-30 WO PCT/US1988/002991 patent/WO1989001779A1/en not_active Ceased
- 1988-08-30 CA CA000576111A patent/CA1336489C/en not_active Expired - Fee Related
- 1988-08-30 JP JP63507516A patent/JP2791074B2/ja not_active Expired - Fee Related
-
1989
- 1989-04-27 FI FI892005A patent/FI100169B/fi not_active IP Right Cessation
- 1989-04-28 NO NO89891787A patent/NO891787L/no unknown
- 1989-05-01 DK DK198902119A patent/DK175596B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2791074B2 (ja) | 1998-08-27 |
| DK175596B1 (da) | 2004-12-13 |
| EP0329778B1 (en) | 1995-05-31 |
| IL83687A0 (https=) | 1988-01-31 |
| FI100169B (fi) | 1997-10-15 |
| US5770572A (en) | 1998-06-23 |
| IL83687A (en) | 1995-03-30 |
| WO1989001779A1 (en) | 1989-03-09 |
| EP0329778A1 (en) | 1989-08-30 |
| JPH02502538A (ja) | 1990-08-16 |
| FI892005A0 (fi) | 1989-04-27 |
| CA1336489C (en) | 1995-08-01 |
| DK211989D0 (da) | 1989-05-01 |
| NO891787L (no) | 1989-06-06 |
| DE3853910D1 (de) | 1995-07-06 |
| AU2383988A (en) | 1989-03-31 |
| EP0329778A4 (en) | 1990-12-27 |
| FI892005L (fi) | 1989-04-27 |
| DK211989A (da) | 1989-06-28 |
| DE3853910T2 (de) | 1995-10-12 |
| NO891787D0 (no) | 1989-04-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE123224T1 (de) | Molekulare köder und deren verwendung. | |
| GT199700095A (es) | Derivados 6,5-heterobiciclicos sustituidos. | |
| BR0015506A (pt) | Conjugados de interferon gama, métodos para sua preparação, composições farmacêuticas que compreendem ás moléculas e seu uso no tratamento de doenças | |
| BR9406363A (pt) | Composiçao farmacêutica processo para a preparaçao da mesma uso da mesma e processo para o tratamento de doenças relacionadas com o ácido gástrico | |
| GT199700093A (es) | Derivados 6,6-heterobiciclicos sustituidos. | |
| PT99445A (pt) | Processo para preparacao de derivados do 1,4,7,10-tetraazaciclododecano mono-n--substituidos e de composicoes farmaceuticas que os contem | |
| DK46789D0 (da) | 3-indolpyrodruesyrederivater og farmaceutisk anvendelse deraf | |
| ES2124702T3 (es) | Usos terapeuticos de compuestos que se unen a actina. | |
| BR9910180A (pt) | Composição farmacêutica, processos para o tratamento de uma condição associada com a transmissão reduzida de nicotina, para identificação de um modulador positivo de um agonista receptor nicotìnico e para identificação de um composto, composto, e, uso de um modulador positivo de um agonista receptor nicotìnico | |
| ATE140388T1 (de) | Zusammensetzungen enthaltend omega conotoxin peptide derivate und deren verwendung zur behandlung von ischämie-artigen neuronalen schädigungen | |
| DK0643726T3 (da) | Peptider af humant p53-protein til anvendelse i sammensætninger, som inducerer humant T-celle-respons, og humane p53-protei | |
| ES2117299T3 (es) | Aparato para la inyeccion embrionaria temprana "in ovo". | |
| PT83572B (pt) | Processo para a preparacao de compostos heterociclicos de quinoxalina e de composicoes farmaceuticas que os contem | |
| EE200000039A (et) | MHC II klassi ligandi kasutamine, farmatseutiline kompositsioon, transfekteeritud kasvajarakud, transfekteeritud rakkude ja kasvajarakkude valmistamismeetod ning nende kasutamine | |
| AR003119A1 (es) | Composicion farmaceutica para tratar infecciones virosicas o inhibir el crecimiento de tumores o canceres que comprenden una mezcla de un n- clorofenilcarbamato o un n- clorofeniltiocarbamato y un n- fosfonoglicina y uso de dicha composicion farmaceutica para la manufactura de un medicamento para tratar infecciones virosicas o inhibir el crecimiento de tumores o canceres | |
| DE69724804D1 (de) | Pestizide zusammensetzung und verfahren zur anwendung | |
| ATE147266T1 (de) | Verwendung von lipoxin a 4? und dessen derivaten als antagonisten für trägreagierende anaphylaxmittel | |
| DE3877547D1 (de) | Basisches protein phospholipase a2 aus dem gift der schlangen aus der familie der elapiden, deren aminosaeuresequenz, derivate und fragmente dieses proteins, verfahren um es zu erhalten, therapeutische kompositionen und diagnosemittel, alle dieses protein enthaltend und/oder dessen derivate und/oder dessen fragmente. | |
| ES2073755T3 (es) | Acidos hidroxamicos y n-hidroxiureas antiinflamatorios. | |
| DE3872872D1 (de) | 5-ht3-rezeptor-antagonisten zur behandlung von husten und bronchokonstriktion. | |
| TR199701576T1 (xx) | N-aril-1,2,4,-triazolin-5-onlar. | |
| DE69634510D1 (de) | Streptococcus toxinmutanten und verfahren zu deren anwendung | |
| MX14957A (es) | Nuevos derivados de tetrazol y procedimiento para su preparacion. | |
| DK0482089T3 (da) | Fremgangsmåder til behandling af autoimmun uveoretnitis i mennesker | |
| BR9913718A (pt) | Processo e composição farmacêutica ou veterinária para inibição profilática ou terapêutica de um material ou substância tóxica em um paciente animal humano ou não-humano, e, uso de um dendrìmero aniÈnico ou catiÈnico |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |