ATE120172T1 - Verfahren zur debrominierung von 2-substituierten-5-bromo-6-methoxynaphthalenen. - Google Patents

Verfahren zur debrominierung von 2-substituierten-5-bromo-6-methoxynaphthalenen.

Info

Publication number
ATE120172T1
ATE120172T1 AT90123978T AT90123978T ATE120172T1 AT E120172 T1 ATE120172 T1 AT E120172T1 AT 90123978 T AT90123978 T AT 90123978T AT 90123978 T AT90123978 T AT 90123978T AT E120172 T1 ATE120172 T1 AT E120172T1
Authority
AT
Austria
Prior art keywords
methoxynaphthalenes
debromination
bromo
substituted
alkyl
Prior art date
Application number
AT90123978T
Other languages
English (en)
Inventor
Vincenzo Via Annibale Cannata
Claudio Calzolari
Giancarlo Tamerlani
Original Assignee
Alfa Chem Ital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11156536&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE120172(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alfa Chem Ital filed Critical Alfa Chem Ital
Application granted granted Critical
Publication of ATE120172T1 publication Critical patent/ATE120172T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/37—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by etherified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT90123978T 1990-02-08 1990-12-12 Verfahren zur debrominierung von 2-substituierten-5-bromo-6-methoxynaphthalenen. ATE120172T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT01929990A IT1238008B (it) 1990-02-08 1990-02-08 Procedimento per la debromurazione di 2-sostituiti-5-bromo- 6-metossinaftaleni

Publications (1)

Publication Number Publication Date
ATE120172T1 true ATE120172T1 (de) 1995-04-15

Family

ID=11156536

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90123978T ATE120172T1 (de) 1990-02-08 1990-12-12 Verfahren zur debrominierung von 2-substituierten-5-bromo-6-methoxynaphthalenen.

Country Status (8)

Country Link
US (1) US5107013A (de)
EP (1) EP0440930B2 (de)
AT (1) ATE120172T1 (de)
DE (1) DE69018058T3 (de)
DK (1) DK0440930T3 (de)
ES (1) ES2070258T5 (de)
GR (1) GR3015528T3 (de)
IT (1) IT1238008B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4318069C1 (de) * 1993-06-01 1994-03-31 Cassella Ag Verfahren zur Herstellung von 5-Brom-6-methoxy-1-naphthoesäuremethylester
IT1285567B1 (it) 1996-02-21 1998-06-18 Alfa Chem Ital Nuovo processo per la sintesi del nabumetone
CN110183323A (zh) * 2019-07-09 2019-08-30 重庆医药高等专科学校 D,l-体萘普生的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1168387B (it) * 1981-04-01 1987-05-20 Alfa Farmaceutici Spa Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico
IT1190362B (it) * 1985-05-30 1988-02-16 Zambon Spa Preparazione del (6-metossi-2-naftil)-(1-bormoetil)-chetone e dei suoi derivati

Also Published As

Publication number Publication date
EP0440930A3 (en) 1992-04-08
GR3015528T3 (en) 1995-06-30
DE69018058T3 (de) 2002-04-18
US5107013A (en) 1992-04-21
DE69018058T2 (de) 1995-09-28
IT9019299A1 (it) 1991-08-09
DE69018058D1 (de) 1995-04-27
IT1238008B (it) 1993-06-21
DK0440930T3 (da) 1995-04-10
IT9019299A0 (it) 1990-02-08
ES2070258T5 (es) 2002-02-01
EP0440930B2 (de) 2001-09-12
EP0440930B1 (de) 1995-03-22
ES2070258T3 (es) 1995-06-01
EP0440930A2 (de) 1991-08-14

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties