ATE120087T1 - Aerosolzubereitung von glutathion und verfahren zur erhöhung des glutathionspiegels in der lunge. - Google Patents

Aerosolzubereitung von glutathion und verfahren zur erhöhung des glutathionspiegels in der lunge.

Info

Publication number
ATE120087T1
ATE120087T1 AT90917464T AT90917464T ATE120087T1 AT E120087 T1 ATE120087 T1 AT E120087T1 AT 90917464 T AT90917464 T AT 90917464T AT 90917464 T AT90917464 T AT 90917464T AT E120087 T1 ATE120087 T1 AT E120087T1
Authority
AT
Austria
Prior art keywords
glutathione
lungs
increasing
aerosol preparation
levels
Prior art date
Application number
AT90917464T
Other languages
English (en)
Inventor
Ronald G Crystal
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Application granted granted Critical
Publication of ATE120087T1 publication Critical patent/ATE120087T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT90917464T 1989-11-24 1990-11-23 Aerosolzubereitung von glutathion und verfahren zur erhöhung des glutathionspiegels in der lunge. ATE120087T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/441,521 US5238683A (en) 1989-11-24 1989-11-24 Aerosol preparation of glutathione and a method for augmenting glutathione level in lungs

Publications (1)

Publication Number Publication Date
ATE120087T1 true ATE120087T1 (de) 1995-04-15

Family

ID=23753204

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90917464T ATE120087T1 (de) 1989-11-24 1990-11-23 Aerosolzubereitung von glutathion und verfahren zur erhöhung des glutathionspiegels in der lunge.

Country Status (11)

Country Link
US (2) US5238683A (de)
EP (1) EP0502054B1 (de)
JP (1) JPH0669957B2 (de)
AT (1) ATE120087T1 (de)
AU (1) AU631711B2 (de)
CA (1) CA2069440A1 (de)
DE (1) DE69018092T2 (de)
DK (1) DK0502054T3 (de)
ES (1) ES2069755T3 (de)
GR (1) GR3015530T3 (de)
WO (1) WO1991007997A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6030950A (en) * 1987-07-09 2000-02-29 Ohlenschlaeger; Gerhard Pharmaceutical therapeutic use of glutathione derivative
US5653685A (en) * 1990-10-10 1997-08-05 Lrt, Inc. Method of providing circulation via lung expansion and deflation
USRE36460E (en) * 1990-10-10 1999-12-21 Life Science Holdings, Inc. Method of providing circulation via lung expansion and deflation
US6180596B1 (en) 1995-05-18 2001-01-30 Wisconsin Alumni Research Foundation Methods of inhibiting phospholipase A2 and phospholipase A2 stimulator activities
US5658877A (en) * 1995-05-18 1997-08-19 Wisconsin Alumni Research Foundation Method to treat endotoxin effects by administration of 33 kilodalton phospholipid binding protein
EP0910423A4 (de) * 1996-03-08 1999-12-29 Life Resuscitation Tech Verfahren und vorrichtung zur flüssigen beatmung
US6896899B2 (en) * 1996-12-31 2005-05-24 Antioxidant Pharmaceuticals Corp. Pharmaceutical preparations of glutathione and methods of administration thereof
US6350467B1 (en) * 1996-12-31 2002-02-26 Antioxidant Pharmaceuticals Corp. Pharmaceutical preparations of glutathione and methods of administration thereof
US6013632A (en) * 1997-01-13 2000-01-11 Emory University Compounds and their combinations for the treatment of influenza infection
KR100585242B1 (ko) * 1998-06-23 2006-12-05 교와 핫꼬 고교 가부시끼가이샤 인플루엔자감염증치료용화합물및조성물
CA2407189A1 (en) 2000-05-02 2001-11-08 F. Hoffmann-La Roche Ag New gamma selective retinoids
US7179791B2 (en) * 2001-01-11 2007-02-20 Duke University Inhibiting GS-FDH to modulate NO bioactivity
US20080221029A1 (en) * 2002-10-31 2008-09-11 Regents Of The University Of Colorado Methods for treatment of thiol-containing compound deficient conditions
US20040087527A1 (en) * 2002-10-31 2004-05-06 Day Brian J. Methods for treatment of thiol-containing compound deficient conditions
US7790762B2 (en) * 2002-10-31 2010-09-07 National Jewish Health Compounds and methods for thiol-containing compound efflux and cancer treatment
PL1817006T3 (pl) * 2004-11-07 2013-03-29 F Timothy Guilford Liposomalny preparat do doustnego podawania glutationu (zredukowanego)
US20090068253A1 (en) * 2005-09-06 2009-03-12 Guilford F Timothy Method for the treatment of infection with hhv-6 virus and the amelioration of symptoms related to virus using liposomal encapsulation for delivery of reduced glutathione
WO2014070769A1 (en) * 2012-10-29 2014-05-08 The University Of North Carolina At Chapel Hill Methods and compositions for treating mucosal tissue disorders
EP2956153A4 (de) * 2013-02-15 2017-03-22 Your Energy Systems, LLC Behandlung von klebsiella-pneumoniae-vermittelten krankheiten mit sich entwickelnder antibakterieller resistenz mithilfe von liposomal formuliertem glutathion
AU2017362500A1 (en) 2016-11-17 2019-06-13 Renovion, Inc. Treatment of Respiratory Tract Diseases and Infections with Ascorbic Acid Compositions
CN111615395A (zh) 2017-11-17 2020-09-01 莱诺翁股份有限公司 稳定的抗坏血酸组合物及其使用方法
US11344497B1 (en) 2017-12-08 2022-05-31 Quicksilver Scientific, Inc. Mitochondrial performance enhancement nanoemulsion
US10722465B1 (en) 2017-12-08 2020-07-28 Quicksilber Scientific, Inc. Transparent colloidal vitamin supplement
US11291702B1 (en) 2019-04-15 2022-04-05 Quicksilver Scientific, Inc. Liver activation nanoemulsion, solid binding composition, and toxin excretion enhancement method
IT202000009553A1 (it) 2020-04-30 2021-10-30 Innbiotec Pharma S R L Composizione farmaceutica di derivati del glutatione per l’uso nel trattamento di sindromi respiratorie
CN113252896B (zh) * 2021-05-13 2022-08-09 四川大学华西医院 一款利用肺泡灌洗液中nd1预测急性呼吸窘迫综合征预后的试剂盒

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA909679A (en) * 1972-09-12 Calbiochem Process of and composition for mucolysis
BE788945A (de) * 1971-09-20 1973-03-19 Oreal
US4424216A (en) * 1979-07-31 1984-01-03 The Rockefeller University Method for the reduction of mucin viscosity
DK283180A (da) * 1980-07-01 1982-01-02 Novo Industri As Polypeptider og derivater deraf
US4513005A (en) * 1981-06-18 1985-04-23 Lilly Industries Limited SRS-A antagonists
IT1176983B (it) * 1984-10-16 1987-08-26 Zambon Spa Dipeptidi ad attivita' farmacologica
GB8505285D0 (en) * 1985-03-01 1985-04-03 Beecham Group Plc Compounds
US4710489A (en) * 1985-04-22 1987-12-01 Cornell Research Foundation, Inc. Glutathione delivery system
WO1988007855A1 (en) * 1987-04-09 1988-10-20 Fisons Plc Pharmaceutical compositions containing pentamidine

Also Published As

Publication number Publication date
DE69018092T2 (de) 1995-07-27
AU631711B2 (en) 1992-12-03
AU6885791A (en) 1991-06-26
DK0502054T3 (da) 1995-06-06
EP0502054A4 (en) 1993-02-24
GR3015530T3 (en) 1995-06-30
JPH0669957B2 (ja) 1994-09-07
EP0502054B1 (de) 1995-03-22
EP0502054A1 (de) 1992-09-09
DE69018092D1 (de) 1995-04-27
CA2069440A1 (en) 1991-05-25
US5989521A (en) 1999-11-23
ES2069755T3 (es) 1995-05-16
WO1991007997A1 (en) 1991-06-13
JPH05501263A (ja) 1993-03-11
US5238683A (en) 1993-08-24

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Legal Events

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REN Ceased due to non-payment of the annual fee