ATE110378T1 - Heterocyclische nitromethanderivate. - Google Patents

Heterocyclische nitromethanderivate.

Info

Publication number
ATE110378T1
ATE110378T1 AT89304227T AT89304227T ATE110378T1 AT E110378 T1 ATE110378 T1 AT E110378T1 AT 89304227 T AT89304227 T AT 89304227T AT 89304227 T AT89304227 T AT 89304227T AT E110378 T1 ATE110378 T1 AT E110378T1
Authority
AT
Austria
Prior art keywords
heterocyclic
nitromethane derivatives
inhibitors
derivatives
concerns novel
Prior art date
Application number
AT89304227T
Other languages
English (en)
Inventor
Stephen Paul Brown
Anthony Loren Cooper
Jethro Lawrence Longridge
Jeffrey James Morris
John Preston
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Application granted granted Critical
Publication of ATE110378T1 publication Critical patent/ATE110378T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • G—PHYSICS
    • G10—MUSICAL INSTRUMENTS; ACOUSTICS
    • G10B—ORGANS, HARMONIUMS OR SIMILAR WIND MUSICAL INSTRUMENTS WITH ASSOCIATED BLOWING APPARATUS
    • G10B3/00—Details or accessories
    • G10B3/12—Keys or keyboards; Manuals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/64—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/76—Dibenzothiophenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Multimedia (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Air Bags (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Detergent Compositions (AREA)
  • Pyridine Compounds (AREA)
AT89304227T 1988-04-29 1989-04-27 Heterocyclische nitromethanderivate. ATE110378T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888810203A GB8810203D0 (en) 1988-04-29 1988-04-29 Heterocyclic compounds

Publications (1)

Publication Number Publication Date
ATE110378T1 true ATE110378T1 (de) 1994-09-15

Family

ID=10636116

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89304227T ATE110378T1 (de) 1988-04-29 1989-04-27 Heterocyclische nitromethanderivate.

Country Status (20)

Country Link
US (1) US5102905A (de)
EP (1) EP0340010B1 (de)
JP (1) JPH01316355A (de)
KR (1) KR900016937A (de)
CN (1) CN1037339A (de)
AT (1) ATE110378T1 (de)
AU (1) AU623128B2 (de)
DD (1) DD283817A5 (de)
DE (1) DE68917634D1 (de)
DK (1) DK200889A (de)
FI (1) FI892038L (de)
GB (2) GB8810203D0 (de)
HU (1) HUT49868A (de)
MW (1) MW1389A1 (de)
NO (1) NO891707L (de)
NZ (1) NZ228915A (de)
PT (1) PT90395B (de)
ZA (1) ZA892597B (de)
ZM (1) ZM1889A1 (de)
ZW (1) ZW5989A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL93178A0 (en) * 1989-02-03 1990-11-05 Ici Plc Benzheterocyclyl sulphones
US5250570A (en) * 1990-08-02 1993-10-05 Imperial Chemical Industries Plc Amidobenzene derivatives, compositions and use
GB9016978D0 (en) * 1990-08-02 1990-09-19 Ici Plc Acetamide derivatives
NZ254550A (en) * 1992-09-28 1997-08-22 Pfizer Use of nitrogen-substituted pyrimidines to prepare medicaments useful for treatment or prevention of diabetic complications
AU3162695A (en) * 1994-08-03 1996-03-04 Asta Medica Aktiengesellschaft Indol, indazol, pyridopyrrol and pyridopyrazol derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunomodulating effects
JP3314938B2 (ja) * 1995-06-06 2002-08-19 ファイザー・インコーポレーテッド グリコーゲンホスホリラーゼ抑制剤としての置換されたn−(インドール−2−カルボニル)−グリシンアミド類および誘導体
US7597884B2 (en) 2004-08-09 2009-10-06 Alios Biopharma, Inc. Hyperglycosylated polypeptide variants and methods of use
KR102229001B1 (ko) * 2018-05-31 2021-03-17 주식회사 엘지화학 신규한 화합물 및 이를 이용한 유기 발광 소자
CN110551015B (zh) * 2018-05-31 2022-06-21 株式会社Lg化学 化合物及利用其的有机发光元件

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053633A (en) * 1976-06-24 1977-10-11 The Dow Chemical Company Aryl dibromonitromethyl sulfones
US4670470A (en) * 1979-08-15 1987-06-02 Merck & Co., Inc. Allylsulfoxide enzyme inhibitors
US4309554A (en) * 1980-04-28 1982-01-05 The Dow Chemical Company 3-(2-Thiophenesulfonyl)-2-halopropanenitriles
JPS5740478A (en) * 1980-08-22 1982-03-06 Ono Pharmaceut Co Ltd Rhodanine derivative, its preparation and aldose reductase inhibitor containing rhodanine derivative
EP0252640B1 (de) * 1986-06-30 1991-03-06 Merck & Co. Inc. Alkansulfonamide als Antiglaucoma-Mittel
GB8718619D0 (en) * 1987-08-06 1987-09-09 Ici Plc Pharmaceutical compositions

Also Published As

Publication number Publication date
NO891707D0 (no) 1989-04-25
AU3308089A (en) 1989-11-02
ZW5989A1 (en) 1990-01-03
CN1037339A (zh) 1989-11-22
ZA892597B (en) 1989-12-27
PT90395A (pt) 1989-11-10
JPH01316355A (ja) 1989-12-21
NO891707L (no) 1989-10-30
GB8906822D0 (en) 1989-05-10
AU623128B2 (en) 1992-05-07
GB8810203D0 (en) 1988-06-02
DE68917634D1 (de) 1994-09-29
US5102905A (en) 1992-04-07
FI892038A0 (fi) 1989-04-28
EP0340010A3 (de) 1991-05-15
DK200889A (da) 1989-10-30
EP0340010A2 (de) 1989-11-02
PT90395B (pt) 1995-03-31
HUT49868A (en) 1989-11-28
FI892038A7 (fi) 1989-10-30
DD283817A5 (de) 1990-10-24
NZ228915A (en) 1991-12-23
FI892038L (fi) 1989-10-30
KR900016937A (ko) 1990-11-14
MW1389A1 (en) 1989-12-13
EP0340010B1 (de) 1994-08-24
DK200889D0 (da) 1989-04-25
ZM1889A1 (en) 1990-01-26

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties