ATE109764T1 - Beta-lactamverbindungen und deren herstellung. - Google Patents

Beta-lactamverbindungen und deren herstellung.

Info

Publication number
ATE109764T1
ATE109764T1 AT86117997T AT86117997T ATE109764T1 AT E109764 T1 ATE109764 T1 AT E109764T1 AT 86117997 T AT86117997 T AT 86117997T AT 86117997 T AT86117997 T AT 86117997T AT E109764 T1 ATE109764 T1 AT E109764T1
Authority
AT
Austria
Prior art keywords
group
optionally protected
formula
hydrogen atom
carboxyl
Prior art date
Application number
AT86117997T
Other languages
English (en)
Inventor
Makoto Sumitomo Pharm Sunagawa
-Chome Konohana-K Kasugadenaka
Yoshihito Sumitomo Phar Nozaki
Akira Sumitomo Pharmace Sasaki
Konohana-Ku Chome
Haruki Sumitomo Phar Matsumura
Original Assignee
Sumitomo Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharma filed Critical Sumitomo Pharma
Application granted granted Critical
Publication of ATE109764T1 publication Critical patent/ATE109764T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT86117997T 1985-12-28 1986-12-23 Beta-lactamverbindungen und deren herstellung. ATE109764T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP29699985 1985-12-28
JP18595886 1986-08-07

Publications (1)

Publication Number Publication Date
ATE109764T1 true ATE109764T1 (de) 1994-08-15

Family

ID=26503442

Family Applications (1)

Application Number Title Priority Date Filing Date
AT86117997T ATE109764T1 (de) 1985-12-28 1986-12-23 Beta-lactamverbindungen und deren herstellung.

Country Status (6)

Country Link
US (1) US5134231A (de)
EP (1) EP0229384B1 (de)
JP (1) JPH0796547B2 (de)
AT (1) ATE109764T1 (de)
DE (1) DE3650023T2 (de)
ES (1) ES2061439T3 (de)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
US4344885A (en) * 1980-01-14 1982-08-17 Merck & Co., Inc. Intermediate for the preparation of thienamycin
US4350631A (en) * 1980-12-18 1982-09-21 Merck & Co., Inc. 6- and 4-Substituted-1-azabicyclo[3.2.0]heptan-3,7-dione-2-carboxylates
JPS57123182A (en) * 1980-12-18 1982-07-31 Merck & Co Inc 6- and 4-substituted-1-azabicyclo(3,1,2,0)heptane- 3,7-dione-2-carboxylate
ES514240A0 (es) * 1981-08-03 1984-04-16 Merck & Co Inc Un procedimiento para la prepracion de nuevos derivados de acidos 2-carbamimidoil-1-,carbadestiapen-2-en-3-carboxilados.
DE3581481D1 (de) * 1984-10-31 1991-02-28 Sumitomo Pharma Beta-lactame und ihre herstellung.
EP0184844A1 (de) * 1984-12-13 1986-06-18 Merck & Co. Inc. 2-Alkylen-thio-substituierte 1-Methylcarbapeneme
NZ214691A (en) * 1984-12-27 1988-08-30 Sumitomo Pharma The preparation of carbapenem derivatives and beta-lactam intermediates
US4734497A (en) * 1985-02-19 1988-03-29 Merck & Co., Inc. Intermediates for process for chiral synthesis of 1-β-methyl-carbapenem intermediates
JPS61275267A (ja) * 1985-03-29 1986-12-05 メルク　エンド　カムパニ−　インコ−ポレ−テツド １−β−メチルカルバペネム抗生物質中間体の鏡像異性選択的製造方法
ATE107278T1 (de) * 1985-03-29 1994-07-15 Merck & Co Inc Enantioselektives verfahren zur herstellung von 1-beta-methylcarbapenem- antibiotikumzwischenprodukten.
JPH0635432B2 (ja) * 1985-06-06 1994-05-11 住友製薬株式会社 新規なβ−ラクタム化合物
US4892961A (en) * 1985-07-31 1990-01-09 Sumitomo Pharmaceuticals Company, Limited Amino acid derivatives, and their production
JPS6229577A (ja) * 1985-07-31 1987-02-07 Sumitomo Pharmaceut Co Ltd オキサゾリジン誘導体
JPH0657683B2 (ja) * 1985-11-15 1994-08-03 住友製薬株式会社 光学活性アミノ酸誘導体
EP0213610A1 (de) * 1985-08-31 1987-03-11 Lederle (Japan) Ltd. Azetidin-2-on-Derivate und Verfahren zu ihrer Herstellung
JPS62103063A (ja) * 1985-10-29 1987-05-13 Sagami Chem Res Center アゼチジノン誘導体の製造方法
GB8528380D0 (en) * 1985-11-18 1985-12-24 Ici Plc Process
GB8531638D0 (en) * 1985-12-23 1986-02-05 Ici Plc Chemical compounds

Also Published As

Publication number Publication date
JPH0796547B2 (ja) 1995-10-18
EP0229384A2 (de) 1987-07-22
JPS63165349A (ja) 1988-07-08
ES2061439T3 (es) 1994-12-16
EP0229384A3 (en) 1989-08-23
US5134231A (en) 1992-07-28
DE3650023D1 (de) 1994-09-15
EP0229384B1 (de) 1994-08-10
DE3650023T2 (de) 1994-11-24

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties