ATE109467T1 - Verwendung von 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropy idinderivaten als freie radikalfänger. - Google Patents
Verwendung von 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropy idinderivaten als freie radikalfänger.Info
- Publication number
- ATE109467T1 ATE109467T1 AT92400289T AT92400289T ATE109467T1 AT E109467 T1 ATE109467 T1 AT E109467T1 AT 92400289 T AT92400289 T AT 92400289T AT 92400289 T AT92400289 T AT 92400289T AT E109467 T1 ATE109467 T1 AT E109467T1
- Authority
- AT
- Austria
- Prior art keywords
- free radical
- compounds
- tetrahydropyide
- trifluoromethylphenyl
- scraper
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Liquid Crystal Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9101283A FR2672213B1 (fr) | 1991-02-05 | 1991-02-05 | Utilisation de derives 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridiniques comme capteurs de radicaux libres. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE109467T1 true ATE109467T1 (de) | 1994-08-15 |
Family
ID=9409370
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92400289T ATE109467T1 (de) | 1991-02-05 | 1992-02-05 | Verwendung von 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropy idinderivaten als freie radikalfänger. |
Country Status (13)
Country | Link |
---|---|
US (1) | US5292745A (de) |
EP (1) | EP0498718B1 (de) |
JP (1) | JP3471820B2 (de) |
AT (1) | ATE109467T1 (de) |
AU (1) | AU649099B2 (de) |
CA (1) | CA2060616C (de) |
DE (1) | DE69200284T2 (de) |
DK (1) | DK0498718T3 (de) |
ES (1) | ES2061319T3 (de) |
FR (1) | FR2672213B1 (de) |
HU (2) | HU212945B (de) |
IE (1) | IE66593B1 (de) |
MX (1) | MX9200485A (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2662442A1 (fr) * | 1990-05-23 | 1991-11-29 | Midy Spa | Trifluoromethylphenyltetrahydropyridines n-substituees procede pour leur preparation, intermediaires du procede et compositions pharmaceutiques les contenant. |
FR2702656B1 (fr) * | 1993-03-18 | 1995-06-16 | Sanofi Elf | Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments cardioprotecteurs. |
FR2740343B1 (fr) * | 1995-10-26 | 1999-01-22 | Sanofi Sa | Utilisation de la 1-(2-napht-2-yl-ethyl)-4- (3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine pour la preparation de medicaments destines au traitement de la sclerose laterale amyotrophique |
ES2159362T3 (es) * | 1995-10-26 | 2001-10-01 | Sanofi Synthelabo | Utilizacion de la 1-(2-naft-2-iletil)-4-(3-trifluorometilfenil)-1,2,3,6-tetrahidropiridina para la preparacion de medicamentos destinados para el tratamiento de la esclerosis lateral amiotrofica. |
FR2763847B1 (fr) | 1997-05-28 | 2003-06-06 | Sanofi Sa | Utilisation de tetrahydropyridines 4-substituees pour fabriquer des medicaments agissant sur le tgf-beta-1 |
CA2353529C (en) * | 1998-12-01 | 2009-11-17 | Alexandre T. Rotta | Method for reducing free-radical induced injury |
BR0212151A (pt) * | 2001-08-29 | 2004-08-24 | Alcon Inc | Uso de compostos para tratar condições resultantes de dano ao nervo corneano após cirurgias de lasik e outras oculares ou traumas |
US7064211B2 (en) * | 2002-03-22 | 2006-06-20 | Eisai Co., Ltd. | Hemiasterlin derivatives and uses thereof |
JP2008504278A (ja) * | 2004-06-24 | 2008-02-14 | インサイト・コーポレイション | アミド化合物およびその医薬としての使用 |
CA2589565A1 (en) * | 2004-06-24 | 2006-01-05 | Incyte Corporation | Amido compounds and their use as pharmaceuticals |
JP2008504275A (ja) * | 2004-06-24 | 2008-02-14 | インサイト・コーポレイション | N−置換ピペリジンおよびその医薬としての使用 |
US7687665B2 (en) * | 2004-06-24 | 2010-03-30 | Incyte Corporation | 2-methylprop anamides and their use as pharmaceuticals |
AU2005273986A1 (en) * | 2004-08-10 | 2006-02-23 | Incyte Corporation | Amido compounds and their use as pharmaceuticals |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4691019A (en) * | 1981-03-11 | 1987-09-01 | Sanofi | Anorectic agent; 4-(3-trifluoromethylphenyl)-1-(2-cyanoethyl)-1,2,3,6-tetrahydropyridine |
FR2501682A1 (fr) * | 1981-03-11 | 1982-09-17 | Sanofi Sa | Trifluoromethylphenylpyridines a activite anorexigene, un procede de preparation et compositions pharmaceutiques en contenant |
FR2531707A1 (fr) * | 1982-08-16 | 1984-02-17 | Midy Spa | Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques |
FR2639226B1 (fr) * | 1988-11-18 | 1993-11-05 | Sanofi | Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs |
GB2226269B (en) * | 1988-12-22 | 1992-11-25 | Zdzislaw Bieganski | Cable stripper |
FR2650505B1 (fr) * | 1989-08-07 | 1994-06-03 | Midy Spa | Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles de la motricite intestinale |
FR2662442A1 (fr) * | 1990-05-23 | 1991-11-29 | Midy Spa | Trifluoromethylphenyltetrahydropyridines n-substituees procede pour leur preparation, intermediaires du procede et compositions pharmaceutiques les contenant. |
-
1991
- 1991-02-05 FR FR9101283A patent/FR2672213B1/fr not_active Expired - Fee Related
-
1992
- 1992-02-03 AU AU10655/92A patent/AU649099B2/en not_active Ceased
- 1992-02-04 HU HU9200335A patent/HU212945B/hu not_active IP Right Cessation
- 1992-02-04 CA CA002060616A patent/CA2060616C/en not_active Expired - Fee Related
- 1992-02-04 IE IE920354A patent/IE66593B1/en not_active IP Right Cessation
- 1992-02-04 MX MX9200485A patent/MX9200485A/es not_active IP Right Cessation
- 1992-02-04 JP JP01895192A patent/JP3471820B2/ja not_active Expired - Fee Related
- 1992-02-04 US US07/830,857 patent/US5292745A/en not_active Expired - Lifetime
- 1992-02-05 DE DE69200284T patent/DE69200284T2/de not_active Expired - Fee Related
- 1992-02-05 DK DK92400289.2T patent/DK0498718T3/da active
- 1992-02-05 EP EP92400289A patent/EP0498718B1/de not_active Expired - Lifetime
- 1992-02-05 AT AT92400289T patent/ATE109467T1/de not_active IP Right Cessation
- 1992-02-05 ES ES92400289T patent/ES2061319T3/es not_active Expired - Lifetime
-
1995
- 1995-06-28 HU HU95P/P00485P patent/HU211457A9/hu unknown
Also Published As
Publication number | Publication date |
---|---|
DK0498718T3 (da) | 1994-12-05 |
FR2672213B1 (fr) | 1995-03-10 |
AU649099B2 (en) | 1994-05-12 |
DE69200284T2 (de) | 1995-03-02 |
DE69200284D1 (de) | 1994-09-08 |
IE66593B1 (en) | 1996-01-24 |
EP0498718A1 (de) | 1992-08-12 |
IE920354A1 (en) | 1992-08-12 |
ES2061319T3 (es) | 1994-12-01 |
HU212945B (en) | 1996-12-30 |
CA2060616A1 (en) | 1992-08-06 |
HU9200335D0 (en) | 1992-04-28 |
FR2672213A1 (fr) | 1992-08-07 |
HU211457A9 (en) | 1995-11-28 |
US5292745A (en) | 1994-03-08 |
MX9200485A (es) | 1992-11-01 |
JP3471820B2 (ja) | 2003-12-02 |
EP0498718B1 (de) | 1994-08-03 |
JPH04312528A (ja) | 1992-11-04 |
AU1065592A (en) | 1992-08-13 |
CA2060616C (en) | 2004-04-06 |
HUT62563A (en) | 1993-05-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |