ATE109353T1 - Verfahren zur herstellung eines impfstoffs gegen hepatitis b. - Google Patents
Verfahren zur herstellung eines impfstoffs gegen hepatitis b.Info
- Publication number
- ATE109353T1 ATE109353T1 AT87402743T AT87402743T ATE109353T1 AT E109353 T1 ATE109353 T1 AT E109353T1 AT 87402743 T AT87402743 T AT 87402743T AT 87402743 T AT87402743 T AT 87402743T AT E109353 T1 ATE109353 T1 AT E109353T1
- Authority
- AT
- Austria
- Prior art keywords
- zonal
- subjected
- preparation
- vaccine against
- against hepatitis
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 208000006454 hepatitis Diseases 0.000 title 1
- 231100000283 hepatitis Toxicity 0.000 title 1
- 238000005119 centrifugation Methods 0.000 abstract 2
- 241000700721 Hepatitis B virus Species 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 210000004978 chinese hamster ovary cell Anatomy 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 239000012228 culture supernatant Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000005188 flotation Methods 0.000 abstract 1
- 230000005847 immunogenicity Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 230000001954 sterilising effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8617265A FR2608052B1 (fr) | 1986-12-10 | 1986-12-10 | Procede de preparation d'un vaccin contre l'hepatite b et vaccin obtenu |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE109353T1 true ATE109353T1 (de) | 1994-08-15 |
Family
ID=9341743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87402743T ATE109353T1 (de) | 1986-12-10 | 1987-12-03 | Verfahren zur herstellung eines impfstoffs gegen hepatitis b. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0273811B1 (de) |
| JP (1) | JPS63215639A (de) |
| KR (1) | KR880007732A (de) |
| AT (1) | ATE109353T1 (de) |
| CA (1) | CA1306689C (de) |
| DE (1) | DE3750330T2 (de) |
| DK (1) | DK645687A (de) |
| FR (1) | FR2608052B1 (de) |
| IL (1) | IL84729A (de) |
| NO (1) | NO171147C (de) |
| PT (1) | PT86321B (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1073604A (zh) * | 1991-12-01 | 1993-06-30 | 高真南 | 制备高免疫原性乙型肝炎疫苗的方法 |
| WO1993012815A1 (en) * | 1991-12-27 | 1993-07-08 | Gensci Limited | Method for obtaining recombinant surface antigen of hepatitis b, antigen and vaccine based on it |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1356413A (en) * | 1971-09-09 | 1974-06-12 | Pfizer Ltd | Method of obtaining purified australia antigen from blood serum |
| US4088748A (en) * | 1976-11-02 | 1978-05-09 | Merck & Co., Inc. | Hepatitis B surface antigen |
| US4162192A (en) * | 1978-09-28 | 1979-07-24 | Juridical Foundation | Method for purification of HBs antigen |
| FR2560890B1 (fr) * | 1984-03-07 | 1987-10-16 | Grp Genie Genetique | Composition utile pour la fabrication de vaccins contenant des particules portant l'antigene de surface du virus de l'hepatite b et le recepteur de l'albumine serique humaine polymerisee, cellules animales capables de produire de telles particules et procede pour leur obtention |
| US4624918A (en) * | 1984-07-09 | 1986-11-25 | Genentech, Inc. | Purification process for hepatitis surface antigen and product thereof |
| US4683294A (en) * | 1985-04-03 | 1987-07-28 | Smith Kline Rit, S.A. | Process for the extraction and purification of proteins from culture media producing them |
-
1986
- 1986-12-10 FR FR8617265A patent/FR2608052B1/fr not_active Expired - Lifetime
-
1987
- 1987-12-03 EP EP87402743A patent/EP0273811B1/de not_active Expired - Lifetime
- 1987-12-03 DE DE3750330T patent/DE3750330T2/de not_active Expired - Lifetime
- 1987-12-03 AT AT87402743T patent/ATE109353T1/de not_active IP Right Cessation
- 1987-12-07 IL IL84729A patent/IL84729A/xx not_active IP Right Cessation
- 1987-12-09 CA CA000553878A patent/CA1306689C/en not_active Expired - Lifetime
- 1987-12-09 PT PT86321A patent/PT86321B/pt not_active IP Right Cessation
- 1987-12-09 NO NO875142A patent/NO171147C/no unknown
- 1987-12-09 DK DK645687A patent/DK645687A/da not_active Application Discontinuation
- 1987-12-10 JP JP62313100A patent/JPS63215639A/ja active Pending
- 1987-12-10 KR KR870014091A patent/KR880007732A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK645687A (da) | 1988-06-11 |
| IL84729A (en) | 1993-02-21 |
| CA1306689C (en) | 1992-08-25 |
| EP0273811A2 (de) | 1988-07-06 |
| DE3750330T2 (de) | 1994-11-17 |
| NO171147B (no) | 1992-10-26 |
| PT86321A (fr) | 1988-01-01 |
| FR2608052B1 (fr) | 1990-04-13 |
| EP0273811A3 (en) | 1988-08-03 |
| NO875142L (no) | 1988-06-13 |
| DK645687D0 (da) | 1987-12-09 |
| FR2608052A1 (fr) | 1988-06-17 |
| PT86321B (pt) | 1990-11-07 |
| JPS63215639A (ja) | 1988-09-08 |
| DE3750330D1 (de) | 1994-09-08 |
| IL84729A0 (en) | 1988-05-31 |
| KR880007732A (ko) | 1988-08-29 |
| NO171147C (no) | 1993-02-03 |
| NO875142D0 (no) | 1987-12-09 |
| EP0273811B1 (de) | 1994-08-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |