ATE107656T1 - Verfahren zur herstellung von 14-alpha-hydroxy-4- androsten-3,6,17, trion. - Google Patents
Verfahren zur herstellung von 14-alpha-hydroxy-4- androsten-3,6,17, trion.Info
- Publication number
- ATE107656T1 ATE107656T1 AT90102302T AT90102302T ATE107656T1 AT E107656 T1 ATE107656 T1 AT E107656T1 AT 90102302 T AT90102302 T AT 90102302T AT 90102302 T AT90102302 T AT 90102302T AT E107656 T1 ATE107656 T1 AT E107656T1
- Authority
- AT
- Austria
- Prior art keywords
- alpha
- hydroxy
- preparation
- androsene
- trion
- Prior art date
Links
- CEJLBZWIKQJOAT-UHFFFAOYSA-N dichloroisocyanuric acid Chemical compound ClN1C(=O)NC(=O)N(Cl)C1=O CEJLBZWIKQJOAT-UHFFFAOYSA-N 0.000 title 1
- UDHAKZRCGHAPAZ-NFBMXZEVSA-N (6r,8r,9s,10r,13s,14r)-6,14-dihydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,15,16-decahydrocyclopenta[a]phenanthrene-3,17-dione Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@]4(O)[C@@H]3C[C@@H](O)C2=C1 UDHAKZRCGHAPAZ-NFBMXZEVSA-N 0.000 abstract 1
- UKVVNEHFNYKGMX-KIVPVIKRSA-N (8r,9s,10r,13s,14r)-14-hydroxy-10,13-dimethyl-2,7,8,9,11,12,15,16-octahydro-1h-cyclopenta[a]phenanthrene-3,6,17-trione Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@]4(O)[C@@H]3CC(=O)C2=C1 UKVVNEHFNYKGMX-KIVPVIKRSA-N 0.000 abstract 1
- 102000014654 Aromatase Human genes 0.000 abstract 1
- 108010078554 Aromatase Proteins 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1027824A JPH0643439B2 (ja) | 1989-02-07 | 1989-02-07 | 光による６β，１４α‐ジヒドロキシ‐４‐アンドロステン‐３，１７‐ジオンの６β位水酸基の酸化方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE107656T1 true ATE107656T1 (de) | 1994-07-15 |
Family
ID=12231698
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90102302T ATE107656T1 (de) | 1989-02-07 | 1990-02-06 | Verfahren zur herstellung von 14-alpha-hydroxy-4- androsten-3,6,17, trion. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US5098535A (de) |
| EP (1) | EP0382162B1 (de) |
| JP (1) | JPH0643439B2 (de) |
| AT (1) | ATE107656T1 (de) |
| DE (1) | DE69010025T2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06225793A (ja) * | 1992-11-27 | 1994-08-16 | Nippon Kayaku Co Ltd | ６β，１４α−ジヒドロキシ−４−アンドロステン−３，１７−ジオンの新規製造法 |
| EP0626388A3 (en) * | 1993-05-28 | 1996-06-19 | Nippon Kayaku Kk | 14alpha-hydroxy-4-androstene-3,6,17-trione hydrate crystal and process for producing same. |
| LT2916901T (lt) | 2012-11-12 | 2020-10-12 | Hollister Incorporated | Pertraukiamas kateterio mazgas |
| WO2014077886A1 (en) | 2012-11-14 | 2014-05-22 | Hollister Incorporated | Disposable catheter with selectively degradable inner core |
| AU2014346748B2 (en) | 2013-11-08 | 2018-05-10 | Hollister Incorporated | Oleophilic lubricated catheters |
| AU2014362360B2 (en) | 2013-12-12 | 2020-01-02 | Hollister Incorporated | Flushable catheters |
| ES2802950T3 (es) | 2013-12-12 | 2021-01-22 | Hollister Inc | Catéteres desechables por el inodoro |
| DK3079749T3 (da) | 2013-12-12 | 2019-12-16 | Hollister Inc | Udskyllelige katetre |
| AU2014363933B2 (en) | 2013-12-12 | 2019-10-10 | Hollister Incorporated | Flushable disintegration catheter |
| US11185613B2 (en) | 2015-06-17 | 2021-11-30 | Hollister Incorporated | Selectively water disintegrable materials and catheters made of such materials |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2900382A (en) * | 1952-06-28 | 1959-08-18 | Syntex Sa | Method of making delta4,6 steroid compounds from delta4 steroid compounds |
| DE3873200T2 (de) * | 1987-02-06 | 1993-02-25 | Snow Brand Milk Prod Co Ltd | Neue androst-4-en-3,17-dion-derivate und verfahren zur herstellung. |
| JPS63192794A (ja) * | 1987-02-06 | 1988-08-10 | Snow Brand Milk Prod Co Ltd | １４α−ヒドロキシ−４−アンドロステン−３，６，１７−トリオン |
-
1989
- 1989-02-07 JP JP1027824A patent/JPH0643439B2/ja not_active Expired - Lifetime
-
1990
- 1990-02-06 DE DE69010025T patent/DE69010025T2/de not_active Expired - Fee Related
- 1990-02-06 US US07/475,502 patent/US5098535A/en not_active Expired - Fee Related
- 1990-02-06 EP EP90102302A patent/EP0382162B1/de not_active Expired - Lifetime
- 1990-02-06 AT AT90102302T patent/ATE107656T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02207095A (ja) | 1990-08-16 |
| DE69010025T2 (de) | 1994-12-15 |
| EP0382162A2 (de) | 1990-08-16 |
| EP0382162B1 (de) | 1994-06-22 |
| US5098535A (en) | 1992-03-24 |
| DE69010025D1 (de) | 1994-07-28 |
| JPH0643439B2 (ja) | 1994-06-08 |
| EP0382162A3 (de) | 1991-03-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |