ATE104977T1 - Zwischenprodukt fuer 1-carba(dethia)cephalosporin. - Google Patents

Zwischenprodukt fuer 1-carba(dethia)cephalosporin.

Info

Publication number
ATE104977T1
ATE104977T1 AT8989306173T AT89306173T ATE104977T1 AT E104977 T1 ATE104977 T1 AT E104977T1 AT 8989306173 T AT8989306173 T AT 8989306173T AT 89306173 T AT89306173 T AT 89306173T AT E104977 T1 ATE104977 T1 AT E104977T1
Authority
AT
Austria
Prior art keywords
dethia
carba
cephalosporin
cephem
nitrobenzyl
Prior art date
Application number
AT8989306173T
Other languages
English (en)
Inventor
Chistina Clara Bodurow
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE104977T1 publication Critical patent/ATE104977T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/02—Preparation
    • C07D463/06—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT8989306173T 1988-06-22 1989-06-19 Zwischenprodukt fuer 1-carba(dethia)cephalosporin. ATE104977T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20959688A 1988-06-22 1988-06-22
EP89306173A EP0348124B1 (de) 1988-06-22 1989-06-19 Zwischenprodukt für 1-Carba(dethia)cephalosporin

Publications (1)

Publication Number Publication Date
ATE104977T1 true ATE104977T1 (de) 1994-05-15

Family

ID=22779423

Family Applications (1)

Application Number Title Priority Date Filing Date
AT8989306173T ATE104977T1 (de) 1988-06-22 1989-06-19 Zwischenprodukt fuer 1-carba(dethia)cephalosporin.

Country Status (10)

Country Link
EP (1) EP0348124B1 (de)
JP (1) JP2809711B2 (de)
KR (1) KR0138264B1 (de)
AT (1) ATE104977T1 (de)
CA (1) CA1334971C (de)
DE (1) DE68914888T2 (de)
ES (1) ES2063129T3 (de)
HU (1) HU207864B (de)
IE (1) IE63268B1 (de)
IL (1) IL90660A0 (de)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208515A (en) * 1973-02-23 1980-06-17 Eli Lilly And Company 3-Halo cephalosporins
IE49377B1 (en) * 1979-02-01 1985-10-02 Lilly Co Eli Process for preparation of beta-lactam compounds
IL76367A0 (en) * 1984-09-17 1986-01-31 Lilly Co Eli Improved process for cephalsporin intermediates
US4665171A (en) * 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics
US4714760A (en) * 1985-08-20 1987-12-22 Bristol-Myers Company Cephalosporin intermediates
US4782144A (en) * 1987-09-14 1988-11-01 Eli Lilly And Company 1-carba(dethia)-3-hydroxy-3-cephem ester crystalline and crystalline solvate thereof

Also Published As

Publication number Publication date
HUT50341A (en) 1990-01-29
JPH0245484A (ja) 1990-02-15
EP0348124A2 (de) 1989-12-27
CA1334971C (en) 1995-03-28
EP0348124A3 (en) 1990-05-09
EP0348124B1 (de) 1994-04-27
IE892017L (en) 1989-12-22
DE68914888D1 (de) 1994-06-01
ES2063129T3 (es) 1995-01-01
IE63268B1 (en) 1995-04-05
DE68914888T2 (de) 1994-09-15
JP2809711B2 (ja) 1998-10-15
IL90660A0 (en) 1990-01-18
KR0138264B1 (ko) 1998-05-15
HU207864B (en) 1993-06-28
KR900000363A (ko) 1990-01-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee