ATA269087A - Neue dopamin-beta-hydroxylaseinhibitoren - Google Patents
Neue dopamin-beta-hydroxylaseinhibitorenInfo
- Publication number
- ATA269087A ATA269087A AT0269087A AT269087A ATA269087A AT A269087 A ATA269087 A AT A269087A AT 0269087 A AT0269087 A AT 0269087A AT 269087 A AT269087 A AT 269087A AT A269087 A ATA269087 A AT A269087A
- Authority
- AT
- Austria
- Prior art keywords
- inhibitors
- hydroxylas
- dopamine beta
- new dopamine
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Processing Of Solid Wastes (AREA)
- Fire-Extinguishing Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86026386A | 1986-05-06 | 1986-05-06 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA269087A true ATA269087A (de) | 1988-09-15 |
| AT387967B AT387967B (de) | 1989-04-10 |
Family
ID=25332828
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87106440T ATE113283T1 (de) | 1986-05-06 | 1987-05-04 | Dopamin-beta-hydroxylasehemmer. |
| AT0269087A AT387967B (de) | 1986-05-06 | 1987-10-12 | Neue dopamin-beta-hydroxylaseinhibitoren |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87106440T ATE113283T1 (de) | 1986-05-06 | 1987-05-04 | Dopamin-beta-hydroxylasehemmer. |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0244803B1 (de) |
| JP (1) | JP2581556B2 (de) |
| KR (1) | KR950013028B1 (de) |
| CN (1) | CN87103323A (de) |
| AT (2) | ATE113283T1 (de) |
| AU (1) | AU596410B2 (de) |
| CA (1) | CA1334199C (de) |
| DE (1) | DE3750685T2 (de) |
| DK (1) | DK229187A (de) |
| ES (1) | ES2065881T3 (de) |
| FI (1) | FI871981A (de) |
| HU (1) | HU198479B (de) |
| IL (1) | IL82401A0 (de) |
| NO (1) | NO871861L (de) |
| NZ (1) | NZ220184A (de) |
| PT (1) | PT84823B (de) |
| ZA (1) | ZA873176B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4634711A (en) * | 1985-08-02 | 1987-01-06 | Smithkline Beckman Corporation | Pyridylalkyl imidazole-2-thiols |
| US4686231A (en) * | 1985-12-12 | 1987-08-11 | Smithkline Beckman Corporation | Inhibition of 5-lipoxygenase products |
| FI91754C (fi) * | 1986-12-02 | 1994-08-10 | Tanabe Seiyaku Co | Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi |
| EP0277384A3 (de) * | 1986-12-24 | 1990-05-23 | Janssen Pharmaceutica N.V. | 1H-Imidazol-5-Kohlensäurederivate |
| EP0285356A3 (de) * | 1987-03-30 | 1989-05-31 | Smithkline Beecham Corporation | Dopamin-beta-hydroxylase-Hemmer |
| US4839375A (en) * | 1987-07-28 | 1989-06-13 | Merrell Dow Pharmaceuticals Inc. | (Aryl or heteroaromatic methyl)-2,2'-bi-1H-imidazoles and their use as anti-hypertensive agents |
| HU202516B (en) * | 1987-10-02 | 1991-03-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing (2-thenyl)-thiourea derivatives and yield increasing agents comprising such compounds |
| CA2002247A1 (en) * | 1988-12-01 | 1990-06-01 | Lawrence I. Kruse | Dopamine-.beta.-hydroxylase inhibitors |
| CA2002246A1 (en) * | 1988-12-01 | 1990-06-01 | Lawrence I. Kruse | Dopamine-.beta.-hydroxylase inhibitors |
| EP0449445A3 (en) * | 1990-03-27 | 1993-08-25 | Pfizer Inc. | Preparation of beta-ketoesters useful in preparing quinolone antibiotics |
| US5635521A (en) * | 1991-09-23 | 1997-06-03 | Sandoz Ltd. | Imidazolylmethyl-pyridines |
| DE19627310A1 (de) * | 1996-06-27 | 1998-01-02 | Schering Ag | Imidazolderivate als Stickstoffmonoxid-Synthase-Inhibitoren |
| GB2393958A (en) * | 2002-10-11 | 2004-04-14 | Portela & Ca Sa | Peripherally-selective imidazole inhibitors of dopamine-beta-hydroxylase |
| US7649007B2 (en) | 2006-08-15 | 2010-01-19 | Wyeth Llc | Oxazolidine derivatives as PR modulators |
| US7618989B2 (en) | 2006-08-15 | 2009-11-17 | Wyeth | Tricyclic oxazolidone derivatives useful as PR modulators |
| US7538107B2 (en) | 2006-08-15 | 2009-05-26 | Wyeth | Oxazinan-2-one derivatives useful as PR modulators |
| US7652018B2 (en) | 2006-08-15 | 2010-01-26 | Wyeth Llc | Imidazolidin-2-one derivatives useful as PR modulators |
| WO2009097416A1 (en) * | 2008-01-29 | 2009-08-06 | Vanda Pharmaceuticals, Inc. | Imidazolylalkyl- pyridines as dbh inhibitors |
| CN103214421B (zh) * | 2012-12-11 | 2016-03-02 | 上海博康精细化工有限公司 | 2-巯基-1-甲基咪唑的工业化生产方法 |
| AU2022213938A1 (en) | 2021-01-26 | 2023-09-07 | Asieris Pharmaceuticals (Shanghai) Co., Ltd. | Pathway modulator, pharmaceutical composition having same, use thereof, and therapeutic method using same |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE312877C (de) * | ||||
| GB1155580A (en) * | 1965-10-21 | 1969-06-18 | Geigy Ag J R | New Imidazole Derivatives their Production and Use |
| FR2073427A1 (en) * | 1969-11-28 | 1971-10-01 | Sogeras | 4-methyl-5-ethyl-n-heterocyclic thiazoles - with antianoxic activity |
| EP0003732B1 (de) * | 1978-02-01 | 1983-10-19 | The Wellcome Foundation Limited | Imidazolderivate und deren Salze, deren Herstellung sowie deren pharmazeutische Zusammensetzungen |
| GB2028317B (en) * | 1978-08-15 | 1982-11-10 | Pfizer Ltd | 2-(imidazol-1-ylmethyl)-pyridine and -quinoline thromboxane synthetase inhibitors |
| GR73560B (de) * | 1979-02-24 | 1984-03-15 | Pfizer | |
| DE3128277A1 (de) * | 1981-07-17 | 1983-02-03 | A. Nattermann & Cie GmbH, 5000 Köln | (omega)-(5-(1-imidazolylmethyl)-thien-2-y1)-alkancarbonsaeuren und deren derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| DE3228266A1 (de) * | 1982-07-29 | 1984-02-02 | A. Nattermann & Cie GmbH, 5000 Köln | Imidazolylalkylthiophene, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| DE3300795A1 (de) * | 1983-01-12 | 1984-07-12 | Bayer Ag, 5090 Leverkusen | Substituierte 4-imidazolyl-pyrazole, verfahren zu ihrer herstellung sowie diese enthaltende arzneimittel |
| US4532331A (en) * | 1983-04-12 | 1985-07-30 | Smithkline Beckman Corporation | 1-Benzyl-2-aminomethyl imidazole derivatives |
| PT78388B (en) * | 1983-04-12 | 1986-09-15 | Smithkline Beckman Corp | Dopamine-beta-hydroxylase inhibitors |
| JPS6289956A (ja) * | 1985-06-19 | 1987-04-24 | Daicel Chem Ind Ltd | 光発色画像組成物 |
| US4634711A (en) * | 1985-08-02 | 1987-01-06 | Smithkline Beckman Corporation | Pyridylalkyl imidazole-2-thiols |
-
1987
- 1987-05-01 IL IL82401A patent/IL82401A0/xx not_active IP Right Cessation
- 1987-05-01 JP JP62106478A patent/JP2581556B2/ja not_active Expired - Fee Related
- 1987-05-04 ES ES87106440T patent/ES2065881T3/es not_active Expired - Lifetime
- 1987-05-04 PT PT84823A patent/PT84823B/pt not_active IP Right Cessation
- 1987-05-04 EP EP87106440A patent/EP0244803B1/de not_active Expired - Lifetime
- 1987-05-04 DE DE3750685T patent/DE3750685T2/de not_active Expired - Fee Related
- 1987-05-04 ZA ZA873176A patent/ZA873176B/xx unknown
- 1987-05-04 AU AU72463/87A patent/AU596410B2/en not_active Ceased
- 1987-05-04 NZ NZ220184A patent/NZ220184A/en unknown
- 1987-05-04 AT AT87106440T patent/ATE113283T1/de not_active IP Right Cessation
- 1987-05-05 HU HU872013A patent/HU198479B/hu not_active IP Right Cessation
- 1987-05-05 NO NO871861A patent/NO871861L/no unknown
- 1987-05-05 CA CA000536384A patent/CA1334199C/en not_active Expired - Fee Related
- 1987-05-05 DK DK229187A patent/DK229187A/da not_active Application Discontinuation
- 1987-05-05 FI FI871981A patent/FI871981A/fi not_active Application Discontinuation
- 1987-05-05 CN CN198787103323A patent/CN87103323A/zh active Pending
- 1987-05-06 KR KR1019870004414A patent/KR950013028B1/ko not_active IP Right Cessation
- 1987-10-12 AT AT0269087A patent/AT387967B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT84823B (pt) | 1989-12-29 |
| DK229187A (da) | 1987-11-07 |
| EP0244803B1 (de) | 1994-10-26 |
| AU596410B2 (en) | 1990-05-03 |
| KR870011104A (ko) | 1987-12-21 |
| KR950013028B1 (ko) | 1995-10-24 |
| HU198479B (en) | 1989-10-30 |
| JP2581556B2 (ja) | 1997-02-12 |
| NO871861L (no) | 1987-11-09 |
| EP0244803A2 (de) | 1987-11-11 |
| FI871981A (fi) | 1987-11-07 |
| NO871861D0 (no) | 1987-05-05 |
| NZ220184A (en) | 1990-04-26 |
| HUT44029A (en) | 1988-01-28 |
| CA1334199C (en) | 1995-01-31 |
| AT387967B (de) | 1989-04-10 |
| FI871981A0 (fi) | 1987-05-05 |
| DE3750685T2 (de) | 1995-03-02 |
| DK229187D0 (da) | 1987-05-05 |
| EP0244803A3 (de) | 1991-01-16 |
| DE3750685D1 (de) | 1994-12-01 |
| CN87103323A (zh) | 1988-02-03 |
| ATE113283T1 (de) | 1994-11-15 |
| AU7246387A (en) | 1987-11-12 |
| PT84823A (en) | 1987-06-01 |
| JPH01100160A (ja) | 1989-04-18 |
| ZA873176B (en) | 1987-10-28 |
| ES2065881T3 (es) | 1995-03-01 |
| IL82401A0 (en) | 1987-11-30 |
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| IL64081A0 (en) | Novel guanidine derivatives | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |