ATA180277A - Verfahren zur herstellung neuer 5-sulfonamido- 2-amino-benzoesaeurederivaten sowie ihrer saeureadditonssalze - Google Patents

Verfahren zur herstellung neuer 5-sulfonamido- 2-amino-benzoesaeurederivaten sowie ihrer saeureadditonssalze

Info

Publication number
ATA180277A
ATA180277A AT771802A AT180277A ATA180277A AT A180277 A ATA180277 A AT A180277A AT 771802 A AT771802 A AT 771802A AT 180277 A AT180277 A AT 180277A AT A180277 A ATA180277 A AT A180277A
Authority
AT
Austria
Prior art keywords
sulfonamido
amino
new
production
benzoic acid
Prior art date
Application number
AT771802A
Other languages
English (en)
Other versions
AT348981B (de
Inventor
Judit Dr Kosary
Endre Dr Kasztreiner
Zsuzsa Dr Huszti
Agnes Kenessey
Gyoergy Dr Cseh
Veronika Szilagyi
Judit Stverteczky
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU76GO00001334A external-priority patent/HU172949B/hu
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ATA180277A publication Critical patent/ATA180277A/de
Application granted granted Critical
Publication of AT348981B publication Critical patent/AT348981B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT180277A 1976-03-18 1977-03-16 Verfahren zur herstellung neuer 5-sulfonamido- 2-amino-benzoesaeurederivate sowie ihrer saeureadditonssalze AT348981B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU76GO00001334A HU172949B (hu) 1976-03-18 1976-03-18 Sposob poluchenija novykh proizvodnykh sul'fonamido-benzojnoj kisloty
DE19762611705 DE2611705A1 (de) 1976-03-18 1976-03-18 N-5-(nitrofurfuryliden-)-1-amino- hydantoin enthaltende kristalloesungsmittel

Publications (2)

Publication Number Publication Date
ATA180277A true ATA180277A (de) 1978-08-15
AT348981B AT348981B (de) 1979-03-12

Family

ID=25770228

Family Applications (1)

Application Number Title Priority Date Filing Date
AT180277A AT348981B (de) 1976-03-18 1977-03-16 Verfahren zur herstellung neuer 5-sulfonamido- 2-amino-benzoesaeurederivate sowie ihrer saeureadditonssalze

Country Status (9)

Country Link
US (1) US4244871A (de)
JP (1) JPS52136146A (de)
AT (1) AT348981B (de)
CA (1) CA1092111A (de)
DE (2) DE2611705A1 (de)
FR (1) FR2344531A1 (de)
GB (1) GB1561243A (de)
NL (1) NL7702991A (de)
SE (1) SE7703068L (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58192820A (ja) * 1982-05-06 1983-11-10 Mochida Pharmaceut Co Ltd 抗ウイルス作用を有する医薬組成物
IT1176613B (it) * 1984-08-14 1987-08-18 Ravizza Spa Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione
JPS61134382A (ja) * 1984-12-04 1986-06-21 Kyorin Pharmaceut Co Ltd 新規なスルファモイル安息香酸誘導体およびその製造法
CN1305454A (zh) 1998-04-20 2001-07-25 藤泽药品工业株式会社 作为cgmp－磷酸二酯酶抑制剂的邻氨基苯甲酸衍生物
AU2004269892B2 (en) * 2003-09-09 2010-03-11 F. Hoffmann-La Roche Ag 1-benzoyl-piperazine derivatives as glycine uptake inhibitors for the treatment of psychoses
WO2005023260A1 (en) * 2003-09-09 2005-03-17 F. Hoffmann-La Roche Ag 1- (2-amino-benzol) -piperazine derivatives as glycine uptake inhibitors for the treatment of psychoses
RU2395502C2 (ru) * 2004-12-09 2010-07-27 Ф.Хоффманн-Ля Рош Аг Производные фенил-пиперазин метанона
NZ555476A (en) * 2004-12-15 2009-09-25 Hoffmann La Roche Bi- and tricyclic substituted phenyl methanones as glycine transporter I (GLYT-1) inhibitors for the treatment of alzheimerÆs disease
US7485637B2 (en) * 2005-01-04 2009-02-03 Hoffmann-La Roche Inc. Benzoyl-tetrahydropiperidine derivatives
CA2593453A1 (en) * 2005-01-06 2006-07-13 F. Hoffmann-La Roche Ag Sulfanyl substituted phenyl methanones as glycine transporter 1 (glyt-1) inhibitors for the treatment of neurological and neuropsychiatric disorders
EP1838308B1 (de) * 2005-01-07 2010-06-30 F. Hoffmann-Roche AG [4-(heteroaryl)piperazin-1-yl]-(2,5-substituierte phenyl)methanon-derivate als glycin-transporter 1 (glyt-1) hemmer zur behandlung von neurologischen und neuropsychiatrischen erkrankungen
BRPI0606730A2 (pt) * 2005-01-18 2009-07-14 Hoffmann La Roche derivados de fenil metanona 2,5-di-substituìdos como inibidores do transportador de glicina 1 (glyt-1) para o tratamento de distúbios neurológicos e neuropsiquiátricos
MX2007008918A (es) * 2005-01-26 2007-08-21 Hoffmann La Roche Derivados de fenil-metanona y su uso como inhibidores del transportador de glicina 1.
DK1848694T3 (da) * 2005-02-07 2010-01-25 Hoffmann La Roche Heterocykliske substituerede phenylmethanoner som inhibitorer af glycintransporter
GB0505086D0 (en) * 2005-03-11 2005-04-20 Glaxo Group Ltd Compounds
CA2729767A1 (en) * 2008-07-07 2010-01-14 Fasgen, Inc. Novel compounds, pharmaceutical compositions containing same, methods of use for same, and methods for preparing same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2910488A (en) * 1958-01-22 1959-10-27 Merck & Co Inc Aniline derivatives
US3346568A (en) * 1961-09-14 1967-10-10 Ciba Geigy Corp 2-amino-5-sulfamyl-benzoic acid hydrazides
FR1403935A (fr) * 1963-06-05 1965-06-25 Ciba Geigy Nouveaux amides d'acides anthraniliques
US3839321A (en) * 1966-07-21 1974-10-01 Smithkline Corp 5-sulfamoyl-n-(2-substituted-ethyl) anthranilic acids
US3522274A (en) * 1967-05-24 1970-07-28 American Home Prod 2,3-dihydro-1-alkyl-7-sulfamoyl-4,1-benzoxazepin-5(1h)-ones
US3843662A (en) * 1971-12-09 1974-10-22 Pfizer 2-halo-5-(substituted piperidino sulfonyl)benzoic acids
DE2232457A1 (de) * 1972-07-01 1974-01-10 Boehringer Mannheim Gmbh Neue 3-alkyl-4-sulfamoylanilinderivate
DE2423847A1 (de) * 1973-05-28 1975-01-02 Ciba Geigy Ag Neue sulfamoylbenzoesaeureamide
CH590260A5 (de) * 1973-07-10 1977-07-29 Ciba Geigy Ag

Also Published As

Publication number Publication date
DE2712023A1 (de) 1977-10-06
CA1092111A (en) 1980-12-23
AT348981B (de) 1979-03-12
DE2611705A1 (de) 1977-09-22
GB1561243A (en) 1980-02-13
FR2344531B1 (de) 1980-04-04
US4244871A (en) 1981-01-13
JPS52136146A (en) 1977-11-14
SE7703068L (sv) 1977-09-19
NL7702991A (nl) 1977-09-20
FR2344531A1 (fr) 1977-10-14

Similar Documents

Publication Publication Date Title
AT367418B (de) Verfahren zur herstellung neuer tetrahydropyridinylindolderivate und ihrer salze
ATA630875A (de) Verfahren zur herstellung neuer derivate der 3-chinolincarbonsaure sowie ihrer saureadditionssalze
ATA922877A (de) Verfahren zur herstellung von neuen ver- aetherten cyclopentan-1-aminen sowie deren salzen
AT294108B (de) Verfahren zur Herstellung neuer Benzamidoäthylpiperazine sowie ihrer Säureadditionssalze
AT348981B (de) Verfahren zur herstellung neuer 5-sulfonamido- 2-amino-benzoesaeurederivate sowie ihrer saeureadditonssalze
AT366682B (de) Verfahren zur herstellung neuer 3-fluor-6piperazinylmorphanthridine und ihrer saeureadditionssalze
AT363474B (de) Verfahren zur herstellung neuer carbostyrilderivate und ihrer pharmazeutisch geeigneten saeureadditionssalze
AT350737B (de) Verfahren zur herstellung neuer n-tetrahydro- furfuryl-noroxymorphone und deren saeure- additionssalzen
AT370421B (de) Verfahren zur herstellung von alkaloiden des leurosin-typs sowie von deren salzen
AT349020B (de) Verfahren zur herstellung neuer 3,4- dihydrocarbostyril-derivate und ihrer saeureadditonssalze
AT347451B (de) Verfahren zur herstellung neuer 2-acetylamino- thiazolderivate sowie ihrer saeureadditions- salze
ATA342176A (de) Verfahren zur herstellung neuer 2-imidazolyl- chinazoline und ihrer salze
AT368993B (de) Verfahren zur herstellung neuer 4-hydroxy-2chinolinon-3-carbonsaeureester und ihrer pharmazeutisch vertraeglichen salze
AT351020B (de) Verfahren zur herstellung neuer 4-phenyl- imidazoline und ihrer saeureadditionssalze
ATA67677A (de) Verfahren zur herstellung neuer 1-(2-phenyl-2- hydroxyaethylamino)-3-phenoxypropan-2-ole und ihrer saeureadditionssalze
AT377256B (de) Verfahren zur herstellung neuer 1-phenaethylimidazol-derivate und ihrer saeureadditionssalze
AT347960B (de) Verfahren zur herstellung neuer hydrazinopyri- dazinderivate und deren salzen
ATA39976A (de) Verfahren zur herstellung neuer 2-6-bis- (aminoacylamino) -anthrachinone sowie ihrer saureadditionssalze
AT352713B (de) Verfahren zur herstellung neuer 1-azidoalkyl- imidazole und ihrer saeureadditionssalze
AT348984B (de) Verfahren zur herstellung neuer omega- aminoalkoxyalkane und ihrer salze
ATA269779A (de) Verfahren zur herstellung neuer pyridobenzo- diazepinone und ihrer salze
ATA8579A (de) Verfahren zur herstellung neuer chinazolon- derivate und ihrer salze
AT350519B (de) Verfahren zur herstellung von neuen omega- amino-alkoxycycloalkanen sowie deren saeure- additonssalzen
ATA799175A (de) Verfahren zur herstellung neuer thiazol-5-carbonsaurederivate und ihrer salze
ATA189379A (de) Verfahren zur herstellung neuer imidazol- derivate und ihrer salze

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties