AT378185B - Verfahren zur herstellung eines neuen cimetidin-monohydrats - Google Patents

Verfahren zur herstellung eines neuen cimetidin-monohydrats

Info

Publication number
AT378185B
AT378185B AT0245282A AT245282A AT378185B AT 378185 B AT378185 B AT 378185B AT 0245282 A AT0245282 A AT 0245282A AT 245282 A AT245282 A AT 245282A AT 378185 B AT378185 B AT 378185B
Authority
AT
Austria
Prior art keywords
cimetidine
monohydrate
producing
new
new cimetidine
Prior art date
Application number
AT0245282A
Other languages
English (en)
Other versions
ATA245282A (de
Inventor
Kalman Dipl Ing Dr Harsanyi
Gyoergy Dipl Ing Dr Domany
Oszkar Dr Fuchs
Lajos Dr Toldy
Gyoergy Dr Fekete
Endre Dr Kasztreiner
Bela Dipl Ing Hegedues
Ferenc Dipl Ing Dr Morasz
Andras Dipl Ing Rado
Tibor Dipl Ing Dr Lang
Arpad Dipl Ing Lazar
Eva Dipl Ing Csongor
Tibor Dipl Ing Dr Balogh
Janos Dr Borvendeg
Jozsef Dr Reiter
Tibor Dipl Ing Somogyi
Margit Dipl Ing Dr Bidlo
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ATA245282A publication Critical patent/ATA245282A/de
Application granted granted Critical
Publication of AT378185B publication Critical patent/AT378185B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT0245282A 1981-06-26 1982-06-24 Verfahren zur herstellung eines neuen cimetidin-monohydrats AT378185B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU811877A HU185636B (en) 1981-06-26 1981-06-26 Process for preparing new cimetidine-hydrate /cimetidine-h/

Publications (2)

Publication Number Publication Date
ATA245282A ATA245282A (de) 1984-11-15
AT378185B true AT378185B (de) 1985-06-25

Family

ID=10956625

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0245282A AT378185B (de) 1981-06-26 1982-06-24 Verfahren zur herstellung eines neuen cimetidin-monohydrats

Country Status (11)

Country Link
US (1) US4579954A (de)
JP (1) JPS584772A (de)
AT (1) AT378185B (de)
BE (1) BE893610A (de)
DE (1) DE3223833A1 (de)
FR (1) FR2508448B1 (de)
GB (1) GB2101991B (de)
GR (1) GR79238B (de)
HU (1) HU185636B (de)
MY (1) MY8700496A (de)
NL (1) NL8202578A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196184B (en) * 1986-09-11 1988-10-28 Richter Gedeon Vegyeszet Process for producing cimetidine-a modification

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0031388A1 (de) * 1979-07-06 1981-07-08 Smithkline Beckman Corporation Verfahren zum herstellen von imidazol-derivaten
AT366033B (de) * 1978-07-19 1982-03-10 Pliva Pharm & Chem Works Verfahren zur herstellung von n-cyano-n'-methyl-n"-(2-((5-methylimidazol-4-yl -methyl)-thioaethyl) -guanidin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE804144A (en) * 1972-09-05 1974-02-28 Smith Kline French Lab H-2-Receptor antihistamines esp gastric acid inhibitors - -N-cyano-N"-(heterocyclyl-alkyl-(thio oxa amino or methylene-alkyl)-guanidines
NZ184893A (en) * 1976-09-21 1980-11-28 Smith Kline French Lab Pure crystalline form of cimetidine a(n-methyl-n-cyano-n-(-2-(5-methyl-4imidazolyl) methylthio) ethyl)-guanidine andpharmaceutical compositions containing it

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT366033B (de) * 1978-07-19 1982-03-10 Pliva Pharm & Chem Works Verfahren zur herstellung von n-cyano-n'-methyl-n"-(2-((5-methylimidazol-4-yl -methyl)-thioaethyl) -guanidin
EP0031388A1 (de) * 1979-07-06 1981-07-08 Smithkline Beckman Corporation Verfahren zum herstellen von imidazol-derivaten

Also Published As

Publication number Publication date
GR79238B (de) 1984-10-22
FR2508448A1 (fr) 1982-12-31
DE3223833A1 (de) 1983-02-24
GB2101991A (en) 1983-01-26
JPS584772A (ja) 1983-01-11
US4579954A (en) 1986-04-01
NL8202578A (nl) 1983-01-17
BE893610A (fr) 1982-12-23
GB2101991B (en) 1985-05-30
FR2508448B1 (fr) 1986-04-18
MY8700496A (en) 1987-12-31
DE3223833C2 (de) 1991-05-29
JPH0343271B2 (de) 1991-07-01
HU185636B (en) 1985-03-28
ATA245282A (de) 1984-11-15

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