AT374485B - Verfahren zur herstellung von salzen der n-(phosphonoacetyl)-l-asparaginsaeure (pala) sowie von deren solvaten - Google Patents
Verfahren zur herstellung von salzen der n-(phosphonoacetyl)-l-asparaginsaeure (pala) sowie von deren solvatenInfo
- Publication number
- AT374485B AT374485B AT0813278A AT813278A AT374485B AT 374485 B AT374485 B AT 374485B AT 0813278 A AT0813278 A AT 0813278A AT 813278 A AT813278 A AT 813278A AT 374485 B AT374485 B AT 374485B
- Authority
- AT
- Austria
- Prior art keywords
- phosphonoacetyl
- pala
- solvates
- asparagic acid
- producing salts
- Prior art date
Links
- ZZKNRXZVGOYGJT-VKHMYHEASA-N (2s)-2-[(2-phosphonoacetyl)amino]butanedioic acid Chemical compound OC(=O)C[C@@H](C(O)=O)NC(=O)CP(O)(O)=O ZZKNRXZVGOYGJT-VKHMYHEASA-N 0.000 title 1
- -1 PHOSPHONOACETYL Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000012453 solvate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85138277A | 1977-11-14 | 1977-11-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA813278A ATA813278A (de) | 1983-09-15 |
| AT374485B true AT374485B (de) | 1984-04-25 |
Family
ID=25310650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0813278A AT374485B (de) | 1977-11-14 | 1978-11-14 | Verfahren zur herstellung von salzen der n-(phosphonoacetyl)-l-asparaginsaeure (pala) sowie von deren solvaten |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5492920A (de) |
| AT (1) | AT374485B (de) |
| AU (1) | AU520966B2 (de) |
| CA (1) | CA1110266A (de) |
| CH (1) | CH636595A5 (de) |
| DE (1) | DE2849396A1 (de) |
| DK (1) | DK149134C (de) |
| FI (1) | FI65261C (de) |
| FR (1) | FR2408617A1 (de) |
| GB (2) | GB2008118B (de) |
| GR (1) | GR65247B (de) |
| NL (1) | NL7811252A (de) |
| NZ (1) | NZ188909A (de) |
| SE (1) | SE439774B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4284579A (en) * | 1979-07-17 | 1981-08-18 | The United States Of America As Represented By The Of The Department Of Health & Human Services | (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt |
-
1978
- 1978-11-13 AU AU41528/78A patent/AU520966B2/en not_active Expired
- 1978-11-14 SE SE7811736A patent/SE439774B/sv not_active IP Right Cessation
- 1978-11-14 DK DK506278A patent/DK149134C/da not_active IP Right Cessation
- 1978-11-14 GB GB7844508A patent/GB2008118B/en not_active Expired
- 1978-11-14 FR FR7832098A patent/FR2408617A1/fr active Granted
- 1978-11-14 GB GB8024584A patent/GB2051070B/en not_active Expired
- 1978-11-14 JP JP13947278A patent/JPS5492920A/ja active Pending
- 1978-11-14 CA CA316,224A patent/CA1110266A/en not_active Expired
- 1978-11-14 NZ NZ188909A patent/NZ188909A/xx unknown
- 1978-11-14 NL NL7811252A patent/NL7811252A/xx not_active Application Discontinuation
- 1978-11-14 CH CH1170578A patent/CH636595A5/fr not_active IP Right Cessation
- 1978-11-14 AT AT0813278A patent/AT374485B/de active
- 1978-11-14 GR GR57650A patent/GR65247B/el unknown
- 1978-11-14 FI FI783467A patent/FI65261C/fi not_active IP Right Cessation
- 1978-11-14 DE DE19782849396 patent/DE2849396A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ATA813278A (de) | 1983-09-15 |
| DE2849396A1 (de) | 1979-05-17 |
| JPS5492920A (en) | 1979-07-23 |
| FI65261B (fi) | 1983-12-30 |
| FR2408617A1 (fr) | 1979-06-08 |
| GB2008118B (en) | 1982-08-04 |
| SE439774B (sv) | 1985-07-01 |
| GB2008118A (en) | 1979-05-31 |
| SE7811736L (sv) | 1979-05-15 |
| GR65247B (en) | 1980-07-31 |
| FI65261C (fi) | 1984-04-10 |
| GB2051070A (en) | 1981-01-14 |
| DK149134C (da) | 1986-07-14 |
| AU4152878A (en) | 1979-05-24 |
| FI783467A (fi) | 1979-05-15 |
| FR2408617B1 (de) | 1983-11-18 |
| CH636595A5 (fr) | 1983-06-15 |
| NL7811252A (nl) | 1979-05-16 |
| AU520966B2 (en) | 1982-03-11 |
| CA1110266A (en) | 1981-10-06 |
| GB2051070B (en) | 1982-08-04 |
| NZ188909A (en) | 1980-10-08 |
| DK506278A (da) | 1979-05-15 |
| DK149134B (da) | 1986-02-10 |
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