AT375363B - Verfahren zur herstellung von 1-(8-chinolyl)2-pyrrolidinon und dessen saeureadditionssalzen - Google Patents

Verfahren zur herstellung von 1-(8-chinolyl)2-pyrrolidinon und dessen saeureadditionssalzen

Info

Publication number
AT375363B
AT375363B AT0582780A AT582780A AT375363B AT 375363 B AT375363 B AT 375363B AT 0582780 A AT0582780 A AT 0582780A AT 582780 A AT582780 A AT 582780A AT 375363 B AT375363 B AT 375363B
Authority
AT
Austria
Prior art keywords
chinolyl
pyrrolidinone
producing
acid addition
addition salts
Prior art date
Application number
AT0582780A
Other languages
English (en)
Other versions
ATA582780A (de
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ATA582780A publication Critical patent/ATA582780A/de
Application granted granted Critical
Publication of AT375363B publication Critical patent/AT375363B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • C07D215/40Nitrogen atoms attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT0582780A 1979-11-30 1980-11-28 Verfahren zur herstellung von 1-(8-chinolyl)2-pyrrolidinon und dessen saeureadditionssalzen AT375363B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7941409 1979-11-30

Publications (2)

Publication Number Publication Date
ATA582780A ATA582780A (de) 1983-12-15
AT375363B true AT375363B (de) 1984-07-25

Family

ID=10509524

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0582780A AT375363B (de) 1979-11-30 1980-11-28 Verfahren zur herstellung von 1-(8-chinolyl)2-pyrrolidinon und dessen saeureadditionssalzen

Country Status (18)

Country Link
US (1) US4366158A (de)
EP (1) EP0030023A3 (de)
JP (1) JPS5699475A (de)
KR (1) KR830004293A (de)
AR (1) AR228442A1 (de)
AT (1) AT375363B (de)
AU (1) AU6495080A (de)
CA (1) CA1156235A (de)
DK (1) DK506480A (de)
ES (1) ES497242A0 (de)
FI (1) FI803704L (de)
GB (1) GB2063868B (de)
GR (1) GR71918B (de)
HU (1) HU185224B (de)
IL (1) IL61580A (de)
IT (1) IT1221040B (de)
NZ (1) NZ195688A (de)
ZA (1) ZA807467B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101157272B1 (ko) 2003-07-22 2012-06-15 아레나 파마슈티칼스, 인크. 5?ht2a 세로토닌 수용체의 조절자로서 이와 관련된질환의 예방 및 치료에 유용한 디아릴 및 아릴헤테로아릴우레아 유도체
GB0507198D0 (en) * 2005-04-08 2005-05-18 Sb Pharmco Inc Process for preparing bicyclic compounds
GB0519758D0 (en) * 2005-09-28 2005-11-09 Glaxo Group Ltd Novel process
EP2508177A1 (de) 2007-12-12 2012-10-10 Glaxo Group Limited Kombinationen mit 3-phenylsulfonyl-8-piperazinyl-1yl-chinolin
US20110021538A1 (en) 2008-04-02 2011-01-27 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
US9126946B2 (en) 2008-10-28 2015-09-08 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto
EP4119141A1 (de) 2015-06-12 2023-01-18 Axovant Sciences GmbH Nelotanserin zur prophylaxe und behandlung von schlafverhaltensstörungen in der rem-phase
JP2018520187A (ja) 2015-07-15 2018-07-26 アクソヴァント サイエンシーズ ゲゼルシャフト ミット ベシュレンクテル ハフツングAxovant Sciences GmbH 神経変性疾患と関連する幻覚の予防および処置のために有用な5−ht2aセロトニン受容体のモジュレーターとしてのジアリールおよびアリールヘテロアリール尿素誘導体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143151A (en) * 1978-07-03 1979-03-06 The Dow Chemical Company Method for treating hyperglycemia in mammals using arylamino benzoic acids

Also Published As

Publication number Publication date
ES8203882A1 (es) 1982-04-01
NZ195688A (en) 1984-09-28
EP0030023A2 (de) 1981-06-10
DK506480A (da) 1981-05-31
ZA807467B (en) 1982-07-28
ATA582780A (de) 1983-12-15
AR228442A1 (es) 1983-03-15
GR71918B (de) 1983-08-17
KR830004293A (ko) 1983-07-09
CA1156235A (en) 1983-11-01
GB2063868B (en) 1984-02-29
ES497242A0 (es) 1982-04-01
IL61580A (en) 1984-06-29
GB2063868A (en) 1981-06-10
IL61580A0 (en) 1980-12-31
EP0030023A3 (de) 1981-09-02
FI803704L (fi) 1981-05-31
HU185224B (en) 1984-12-28
IT1221040B (it) 1990-06-21
US4366158A (en) 1982-12-28
IT8050277A0 (it) 1980-11-28
JPS5699475A (en) 1981-08-10
AU6495080A (en) 1981-06-04

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Legal Events

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ELJ Ceased due to non-payment of the annual fee