ATA582780A - Verfahren zur herstellung von 1-(8-chinolyl)2-pyrrolidinon und dessen saeureadditionssalzen - Google Patents
Verfahren zur herstellung von 1-(8-chinolyl)2-pyrrolidinon und dessen saeureadditionssalzenInfo
- Publication number
- ATA582780A ATA582780A AT0582780A AT582780A ATA582780A AT A582780 A ATA582780 A AT A582780A AT 0582780 A AT0582780 A AT 0582780A AT 582780 A AT582780 A AT 582780A AT A582780 A ATA582780 A AT A582780A
- Authority
- AT
- Austria
- Prior art keywords
- chinolyl
- pyrrolidinone
- producing
- acid addition
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/40—Nitrogen atoms attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7941409 | 1979-11-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA582780A true ATA582780A (de) | 1983-12-15 |
| AT375363B AT375363B (de) | 1984-07-25 |
Family
ID=10509524
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0582780A AT375363B (de) | 1979-11-30 | 1980-11-28 | Verfahren zur herstellung von 1-(8-chinolyl)2-pyrrolidinon und dessen saeureadditionssalzen |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4366158A (de) |
| EP (1) | EP0030023A3 (de) |
| JP (1) | JPS5699475A (de) |
| KR (1) | KR830004293A (de) |
| AR (1) | AR228442A1 (de) |
| AT (1) | AT375363B (de) |
| AU (1) | AU6495080A (de) |
| CA (1) | CA1156235A (de) |
| DK (1) | DK506480A (de) |
| ES (1) | ES497242A0 (de) |
| FI (1) | FI803704L (de) |
| GB (1) | GB2063868B (de) |
| GR (1) | GR71918B (de) |
| HU (1) | HU185224B (de) |
| IL (1) | IL61580A (de) |
| IT (1) | IT1221040B (de) |
| NZ (1) | NZ195688A (de) |
| ZA (1) | ZA807467B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602004000260T2 (de) | 2003-07-22 | 2006-08-24 | Arena Pharmaceuticals, Inc., San Diego | Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen |
| GB0507198D0 (en) * | 2005-04-08 | 2005-05-18 | Sb Pharmco Inc | Process for preparing bicyclic compounds |
| GB0519758D0 (en) * | 2005-09-28 | 2005-11-09 | Glaxo Group Ltd | Novel process |
| US9084742B2 (en) | 2007-12-12 | 2015-07-21 | Axovant Sciences Ltd. | Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-Quinoline |
| WO2009123714A2 (en) | 2008-04-02 | 2009-10-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor |
| US9126946B2 (en) | 2008-10-28 | 2015-09-08 | Arena Pharmaceuticals, Inc. | Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto |
| MX2017016413A (es) | 2015-06-12 | 2018-08-01 | Axovant Sciences Gmbh | Derivados de diaril y arilheteroaril urea como moduladores del receptor 5ht2a de serotonina útiles para la profilaxis y el tratamineto de un trastorno conductual del sueño rem. |
| JP2018520187A (ja) | 2015-07-15 | 2018-07-26 | アクソヴァント サイエンシーズ ゲゼルシャフト ミット ベシュレンクテル ハフツングAxovant Sciences GmbH | 神経変性疾患と関連する幻覚の予防および処置のために有用な５−ｈｔ２ａセロトニン受容体のモジュレーターとしてのジアリールおよびアリールヘテロアリール尿素誘導体 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4143151A (en) * | 1978-07-03 | 1979-03-06 | The Dow Chemical Company | Method for treating hyperglycemia in mammals using arylamino benzoic acids |
-
1980
- 1980-11-24 US US06/209,426 patent/US4366158A/en not_active Expired - Lifetime
- 1980-11-26 GB GB8037872A patent/GB2063868B/en not_active Expired
- 1980-11-28 ZA ZA00807467A patent/ZA807467B/xx unknown
- 1980-11-28 KR KR1019800004552A patent/KR830004293A/ko unknown
- 1980-11-28 EP EP80107463A patent/EP0030023A3/de not_active Ceased
- 1980-11-28 IT IT50277/80A patent/IT1221040B/it active
- 1980-11-28 AT AT0582780A patent/AT375363B/de not_active IP Right Cessation
- 1980-11-28 ES ES497242A patent/ES497242A0/es active Granted
- 1980-11-28 DK DK506480A patent/DK506480A/da not_active Application Discontinuation
- 1980-11-28 JP JP16791880A patent/JPS5699475A/ja active Pending
- 1980-11-28 HU HU802850A patent/HU185224B/hu unknown
- 1980-11-28 NZ NZ195688A patent/NZ195688A/en unknown
- 1980-11-28 FI FI803704A patent/FI803704L/fi not_active Application Discontinuation
- 1980-11-28 CA CA000365722A patent/CA1156235A/en not_active Expired
- 1980-11-28 AR AR283420A patent/AR228442A1/es active
- 1980-11-28 AU AU64950/80A patent/AU6495080A/en not_active Abandoned
- 1980-11-28 IL IL61580A patent/IL61580A/xx unknown
- 1980-11-28 GR GR63493A patent/GR71918B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU6495080A (en) | 1981-06-04 |
| IT1221040B (it) | 1990-06-21 |
| HU185224B (en) | 1984-12-28 |
| IT8050277A0 (it) | 1980-11-28 |
| US4366158A (en) | 1982-12-28 |
| ZA807467B (en) | 1982-07-28 |
| EP0030023A2 (de) | 1981-06-10 |
| JPS5699475A (en) | 1981-08-10 |
| ES8203882A1 (es) | 1982-04-01 |
| CA1156235A (en) | 1983-11-01 |
| GB2063868A (en) | 1981-06-10 |
| IL61580A (en) | 1984-06-29 |
| GR71918B (de) | 1983-08-17 |
| ES497242A0 (es) | 1982-04-01 |
| EP0030023A3 (de) | 1981-09-02 |
| IL61580A0 (en) | 1980-12-31 |
| KR830004293A (ko) | 1983-07-09 |
| AT375363B (de) | 1984-07-25 |
| AR228442A1 (es) | 1983-03-15 |
| NZ195688A (en) | 1984-09-28 |
| DK506480A (da) | 1981-05-31 |
| FI803704L (fi) | 1981-05-31 |
| GB2063868B (en) | 1984-02-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |