AT365189B - Verfahren zur herstellung von neuen trans-dl-5substituierten4,4a,5,6,7,8,8a,9-octahydro-2h-pyrrolo(3,4-g)-chinolinen und den salzen hiervon - Google Patents
Verfahren zur herstellung von neuen trans-dl-5substituierten4,4a,5,6,7,8,8a,9-octahydro-2h-pyrrolo(3,4-g)-chinolinen und den salzen hiervonInfo
- Publication number
- AT365189B AT365189B AT0452579A AT452579A AT365189B AT 365189 B AT365189 B AT 365189B AT 0452579 A AT0452579 A AT 0452579A AT 452579 A AT452579 A AT 452579A AT 365189 B AT365189 B AT 365189B
- Authority
- AT
- Austria
- Prior art keywords
- quinolines
- octahydro
- pyrrolo
- salts
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT10781A AT371464B (de) | 1979-01-22 | 1981-01-13 | Verfahren zur herstellung von neuen trans-dl-4,4a,5,6,7,8,8a,9-octahydro-2h-pyrrolo 3,4-g)chinolin- verbindungen und ihren salzen |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US506279A | 1979-01-22 | 1979-01-22 | |
| US06/031,642 US4235909A (en) | 1979-04-19 | 1979-04-19 | Octahydro-2H-pyrrolo[3,4-g]quinolines |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA452579A ATA452579A (de) | 1981-05-15 |
| AT365189B true AT365189B (de) | 1981-12-28 |
Family
ID=26673871
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0452579A AT365189B (de) | 1979-01-22 | 1979-06-28 | Verfahren zur herstellung von neuen trans-dl-5substituierten4,4a,5,6,7,8,8a,9-octahydro-2h-pyrrolo(3,4-g)-chinolinen und den salzen hiervon |
Country Status (25)
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL65269A0 (en) * | 1981-03-24 | 1982-05-31 | Lilly Co Eli | 6-substituted hexahydroindazolo or hexahydroisoindolo isoquinolines |
| EP0127708B1 (en) * | 1983-06-03 | 1987-09-09 | Eli Lilly And Company | Trans-dl-1-alkyl-6-alkoxyoctahydroquinolines |
| IL73001A0 (en) * | 1983-09-26 | 1984-12-31 | Lilly Co Eli | Improvements in and relating to 6-oxodecahydroquinolines |
| US4595754A (en) * | 1985-03-04 | 1986-06-17 | Eli Lilly And Company | Process for preparing cis N-alkylperhydroquinolines |
| AR067027A1 (es) * | 2007-06-19 | 2009-09-30 | Astrazeneca Ab | Derivados de 2, 3-dihidro-1h-pirrol[3, 4b]quinolin-1-ona, una composicion farmaceutica que los comprende y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la modulacion de la actividad del receptor gaba a. |
| TWI537274B (zh) * | 2011-03-14 | 2016-06-11 | 橘生藥品工業股份有限公司 | 新穎之八氫噻吩并喹啉衍生物、含有其之醫藥組成物及該等之用途 |
-
1979
- 1979-06-26 DK DK268979A patent/DK268979A/da not_active Application Discontinuation
- 1979-06-26 CA CA330,551A patent/CA1131227A/en not_active Expired
- 1979-06-26 IL IL57665A patent/IL57665A/xx unknown
- 1979-06-26 NZ NZ190834A patent/NZ190834A/en unknown
- 1979-06-26 PT PT69828A patent/PT69828A/pt unknown
- 1979-06-27 LU LU81440A patent/LU81440A1/xx unknown
- 1979-06-27 AU AU48444/79A patent/AU528035B2/en not_active Ceased
- 1979-06-27 PH PH22695A patent/PH15118A/en unknown
- 1979-06-27 FR FR7916572A patent/FR2446833A1/fr active Granted
- 1979-06-27 RO RO7997972A patent/RO77442A/ro unknown
- 1979-06-28 BE BE1/9437A patent/BE877328A/xx not_active IP Right Cessation
- 1979-06-28 JP JP8340679A patent/JPS55100385A/ja active Granted
- 1979-06-28 FI FI792047A patent/FI65248C/fi not_active IP Right Cessation
- 1979-06-28 AT AT0452579A patent/AT365189B/de not_active IP Right Cessation
- 1979-06-28 GB GB7922532A patent/GB2040917B/en not_active Expired
- 1979-06-28 CH CH606179A patent/CH641801A5/fr not_active IP Right Cessation
- 1979-06-28 DE DE7979301251T patent/DE2965277D1/de not_active Expired
- 1979-06-28 EP EP79301251A patent/EP0013788B1/en not_active Expired
- 1979-06-29 PL PL1979216721A patent/PL125785B1/pl unknown
- 1979-06-29 DD DD79213989A patent/DD144668A5/de unknown
- 1979-06-29 AR AR277113A patent/AR225012A1/es active
- 1979-06-29 ZA ZA793244A patent/ZA793244B/xx unknown
- 1979-06-29 ES ES482084A patent/ES482084A1/es not_active Expired
- 1979-08-08 IE IE1210/79A patent/IE48295B1/en unknown
- 1979-11-06 FR FR7927312A patent/FR2446835A1/fr active Granted
-
1980
- 1980-05-29 PH PH24086A patent/PH16181A/en unknown
- 1980-07-31 SU SU802790756A patent/SU1113006A3/ru active
-
1983
- 1983-08-25 CH CH464583A patent/CH643258A5/fr not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |