ZA793244B - Octahydro-2h-pyrrolo (3,4-g) quinolines - Google Patents

Octahydro-2h-pyrrolo (3,4-g) quinolines

Info

Publication number
ZA793244B
ZA793244B ZA793244A ZA793244A ZA793244B ZA 793244 B ZA793244 B ZA 793244B ZA 793244 A ZA793244 A ZA 793244A ZA 793244 A ZA793244 A ZA 793244A ZA 793244 B ZA793244 B ZA 793244B
Authority
ZA
South Africa
Prior art keywords
quinolines
octahydro
pyrrolo
Prior art date
Application number
ZA793244A
Other languages
English (en)
Inventor
N Bach
E Kornfeld
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/031,642 external-priority patent/US4235909A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA793244B publication Critical patent/ZA793244B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/227Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA793244A 1979-01-22 1979-06-29 Octahydro-2h-pyrrolo (3,4-g) quinolines ZA793244B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US506279A 1979-01-22 1979-01-22
US06/031,642 US4235909A (en) 1979-04-19 1979-04-19 Octahydro-2H-pyrrolo[3,4-g]quinolines

Publications (1)

Publication Number Publication Date
ZA793244B true ZA793244B (en) 1981-02-25

Family

ID=26673871

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA793244A ZA793244B (en) 1979-01-22 1979-06-29 Octahydro-2h-pyrrolo (3,4-g) quinolines

Country Status (25)

Country Link
EP (1) EP0013788B1 (xx)
JP (1) JPS55100385A (xx)
AR (1) AR225012A1 (xx)
AT (1) AT365189B (xx)
AU (1) AU528035B2 (xx)
BE (1) BE877328A (xx)
CA (1) CA1131227A (xx)
CH (2) CH641801A5 (xx)
DD (1) DD144668A5 (xx)
DE (1) DE2965277D1 (xx)
DK (1) DK268979A (xx)
ES (1) ES482084A1 (xx)
FI (1) FI65248C (xx)
FR (2) FR2446833A1 (xx)
GB (1) GB2040917B (xx)
IE (1) IE48295B1 (xx)
IL (1) IL57665A (xx)
LU (1) LU81440A1 (xx)
NZ (1) NZ190834A (xx)
PH (2) PH15118A (xx)
PL (1) PL125785B1 (xx)
PT (1) PT69828A (xx)
RO (1) RO77442A (xx)
SU (1) SU1113006A3 (xx)
ZA (1) ZA793244B (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL65269A0 (en) * 1981-03-24 1982-05-31 Lilly Co Eli 6-substituted hexahydroindazolo or hexahydroisoindolo isoquinolines
DE3373468D1 (de) * 1983-06-03 1987-10-15 Lilly Co Eli Trans-dl-1-alkyl-6-alkoxyoctahydroquinolines
IL73001A0 (en) * 1983-09-26 1984-12-31 Lilly Co Eli Improvements in and relating to 6-oxodecahydroquinolines
US4595754A (en) * 1985-03-04 1986-06-17 Eli Lilly And Company Process for preparing cis N-alkylperhydroquinolines
AR067027A1 (es) * 2007-06-19 2009-09-30 Astrazeneca Ab Derivados de 2, 3-dihidro-1h-pirrol[3, 4b]quinolin-1-ona, una composicion farmaceutica que los comprende y su uso en la fabricacion de un medicamento para el tratamiento de enfermedades mediadas por la modulacion de la actividad del receptor gaba a.
TWI537274B (zh) 2011-03-14 2016-06-11 橘生藥品工業股份有限公司 新穎之八氫噻吩并喹啉衍生物、含有其之醫藥組成物及該等之用途

Also Published As

Publication number Publication date
ATA452579A (de) 1981-05-15
EP0013788A1 (en) 1980-08-06
DE2965277D1 (en) 1983-06-01
PH16181A (en) 1983-07-25
PH15118A (en) 1982-08-10
ES482084A1 (es) 1980-08-01
JPS55100385A (en) 1980-07-31
BE877328A (fr) 1979-12-28
FI65248B (fi) 1983-12-30
AR225012A1 (es) 1982-02-15
GB2040917B (en) 1983-01-06
IE48295B1 (en) 1984-11-28
PT69828A (en) 1979-07-01
FR2446835A1 (fr) 1980-08-14
EP0013788B1 (en) 1983-04-27
DK268979A (da) 1980-07-23
PL125785B1 (en) 1983-06-30
PL216721A1 (xx) 1980-06-16
IL57665A0 (en) 1979-10-31
IL57665A (en) 1982-11-30
CH643258A5 (fr) 1984-05-30
FR2446833B1 (xx) 1982-03-05
AU528035B2 (en) 1983-04-14
JPS6233233B2 (xx) 1987-07-20
FR2446835B1 (xx) 1982-04-23
GB2040917A (en) 1980-09-03
AU4844479A (en) 1980-07-31
FI792047A (fi) 1980-07-23
NZ190834A (en) 1984-07-06
RO77442A (ro) 1982-10-26
DD144668A5 (de) 1980-10-29
LU81440A1 (fr) 1979-09-12
FI65248C (fi) 1984-04-10
SU1113006A3 (ru) 1984-09-07
CA1131227A (en) 1982-09-07
FR2446833A1 (fr) 1980-08-14
CH641801A5 (fr) 1984-03-15
IE791210L (en) 1980-10-19
AT365189B (de) 1981-12-28

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