AT358037B - Verfahren zur herstellung neuer 1-amino-2- hydroxy-3-heterocyclyloxy-propane und ihrer salze - Google Patents

Verfahren zur herstellung neuer 1-amino-2- hydroxy-3-heterocyclyloxy-propane und ihrer salze

Info

Publication number
AT358037B
AT358037B AT648777A AT648777A AT358037B AT 358037 B AT358037 B AT 358037B AT 648777 A AT648777 A AT 648777A AT 648777 A AT648777 A AT 648777A AT 358037 B AT358037 B AT 358037B
Authority
AT
Austria
Prior art keywords
propanes
heterocyclyloxy
hydroxy
salts
amino
Prior art date
Application number
AT648777A
Other languages
German (de)
English (en)
Other versions
ATA648777A (de
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to AT338079A priority Critical patent/AT358042B/de
Priority to AT337979A priority patent/AT358586B/de
Priority to AT338179A priority patent/AT360021B/de
Publication of ATA648777A publication Critical patent/ATA648777A/de
Application granted granted Critical
Publication of AT358037B publication Critical patent/AT358037B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/69—Two or more oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT648777A 1976-10-05 1977-09-09 Verfahren zur herstellung neuer 1-amino-2- hydroxy-3-heterocyclyloxy-propane und ihrer salze AT358037B (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AT338079A AT358042B (de) 1976-10-05 1979-05-07 Verfahren zur herstellung neuer 1-amino-2- -hydroxy-3-heterocyclyloxy-propane und ihrer salze
AT337979A AT358586B (de) 1976-10-05 1979-05-07 Verfahren zur herstellung neuer 1-amino-2- hydroxy-3-heterocyclyloxy-propane und ihrer salze
AT338179A AT360021B (de) 1976-10-05 1979-05-07 Verfahren zur herstellung neuer 1-amino-2- hydroxy-3-heterocyclyloxy-propane und ihrer salze

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1263576A CH607585A5 (en) 1976-10-05 1976-10-05 Process for the preparation of 2-[3'-(2-(3,4-dimethoxy-phenyl)ethylamino)-2'-hydroxypropoxy]-3-cyanop yridine

Publications (2)

Publication Number Publication Date
ATA648777A ATA648777A (de) 1980-01-15
AT358037B true AT358037B (de) 1980-08-11

Family

ID=4384944

Family Applications (1)

Application Number Title Priority Date Filing Date
AT648777A AT358037B (de) 1976-10-05 1977-09-09 Verfahren zur herstellung neuer 1-amino-2- hydroxy-3-heterocyclyloxy-propane und ihrer salze

Country Status (21)

Country Link
JP (1) JPS5350177A (fr)
AT (1) AT358037B (fr)
AU (1) AU514676B2 (fr)
BE (1) BE858867A (fr)
CA (1) CA1105021A (fr)
CH (1) CH607585A5 (fr)
DE (1) DE2740678A1 (fr)
DK (1) DK402877A (fr)
ES (1) ES462389A1 (fr)
FI (1) FI772681A (fr)
FR (1) FR2367065A1 (fr)
GB (1) GB1591723A (fr)
GR (1) GR71677B (fr)
IE (1) IE45692B1 (fr)
IL (1) IL53013A (fr)
NL (1) NL7710394A (fr)
NO (1) NO773125L (fr)
NZ (1) NZ185267A (fr)
PT (1) PT67048B (fr)
SE (1) SE7710250L (fr)
ZA (1) ZA775698B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK267779A (da) * 1978-06-27 1979-12-28 Merck & Co Inc Fr&mgangsmaade til fremstilling af n-aralkylamino-propoxycyanopyridiner
US4208416A (en) * 1978-06-27 1980-06-17 Merck & Co., Inc. N-Aralkyl containing cyanopyridines
US4210653A (en) * 1978-06-27 1980-07-01 Merck & Co., Inc. Pyridyloxypropanolamines
GB8510146D0 (en) * 1985-04-20 1985-05-30 Smith Kline French Lab Chemical compounds & processes
US4894453A (en) * 1986-06-30 1990-01-16 Toyo Jozo Kabushiki Kaisha 2-substituted alkoxy-3-substituted-pyrazines
AU1580001A (en) * 1999-11-15 2001-05-30 Eli Lilly And Company Process for the preparation of aryloxy propanolamines

Also Published As

Publication number Publication date
GB1591723A (en) 1981-06-24
AU514676B2 (en) 1981-02-19
AU2912577A (en) 1979-04-05
IE45692L (en) 1978-04-05
GR71677B (fr) 1983-06-21
IL53013A (en) 1981-09-13
CA1105021A (fr) 1981-07-14
FR2367065B1 (fr) 1980-10-10
NL7710394A (nl) 1978-04-07
IE45692B1 (en) 1982-10-20
ZA775698B (en) 1978-05-30
IL53013A0 (en) 1977-11-30
ATA648777A (de) 1980-01-15
PT67048B (de) 1979-02-16
NO773125L (no) 1978-04-06
JPS5350177A (en) 1978-05-08
CH607585A5 (en) 1978-09-15
DK402877A (da) 1978-04-06
FR2367065A1 (fr) 1978-05-05
SE7710250L (sv) 1978-04-06
NZ185267A (en) 1979-07-11
BE858867A (fr) 1978-03-20
PT67048A (de) 1977-10-01
DE2740678A1 (de) 1978-04-06
FI772681A (fi) 1978-04-06
ES462389A1 (es) 1978-07-01

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee