CA1105021A - Traduction non-disponible - Google Patents

Traduction non-disponible

Info

Publication number
CA1105021A
CA1105021A CA287,391A CA287391A CA1105021A CA 1105021 A CA1105021 A CA 1105021A CA 287391 A CA287391 A CA 287391A CA 1105021 A CA1105021 A CA 1105021A
Authority
CA
Canada
Prior art keywords
formula
group
compound
hydroxyl
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA287,391A
Other languages
English (en)
Inventor
Herbert Schroter
Franz Ostermayer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy Investments Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Investments Ltd filed Critical Ciba Geigy Investments Ltd
Application granted granted Critical
Publication of CA1105021A publication Critical patent/CA1105021A/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • C07D213/85Nitriles in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA287,391A 1976-10-05 1977-09-23 Traduction non-disponible Expired CA1105021A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1263576A CH607585A5 (en) 1976-10-05 1976-10-05 Process for the preparation of 2-[3'-(2-(3,4-dimethoxy-phenyl)ethylamino)-2'-hydroxypropoxy]-3-cyanop yridine
CH12635/76 1976-10-05

Publications (1)

Publication Number Publication Date
CA1105021A true CA1105021A (fr) 1981-07-14

Family

ID=4384944

Family Applications (1)

Application Number Title Priority Date Filing Date
CA287,391A Expired CA1105021A (fr) 1976-10-05 1977-09-23 Traduction non-disponible

Country Status (21)

Country Link
JP (1) JPS5350177A (fr)
AT (1) AT358037B (fr)
AU (1) AU514676B2 (fr)
BE (1) BE858867A (fr)
CA (1) CA1105021A (fr)
CH (1) CH607585A5 (fr)
DE (1) DE2740678A1 (fr)
DK (1) DK402877A (fr)
ES (1) ES462389A1 (fr)
FI (1) FI772681A (fr)
FR (1) FR2367065A1 (fr)
GB (1) GB1591723A (fr)
GR (1) GR71677B (fr)
IE (1) IE45692B1 (fr)
IL (1) IL53013A (fr)
NL (1) NL7710394A (fr)
NO (1) NO773125L (fr)
NZ (1) NZ185267A (fr)
PT (1) PT67048B (fr)
SE (1) SE7710250L (fr)
ZA (1) ZA775698B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK267779A (da) * 1978-06-27 1979-12-28 Merck & Co Inc Fr&mgangsmaade til fremstilling af n-aralkylamino-propoxycyanopyridiner
US4208416A (en) * 1978-06-27 1980-06-17 Merck & Co., Inc. N-Aralkyl containing cyanopyridines
US4210653A (en) * 1978-06-27 1980-07-01 Merck & Co., Inc. Pyridyloxypropanolamines
GB8510146D0 (en) * 1985-04-20 1985-05-30 Smith Kline French Lab Chemical compounds & processes
US4894453A (en) * 1986-06-30 1990-01-16 Toyo Jozo Kabushiki Kaisha 2-substituted alkoxy-3-substituted-pyrazines
AU1580001A (en) * 1999-11-15 2001-05-30 Eli Lilly And Company Process for the preparation of aryloxy propanolamines

Also Published As

Publication number Publication date
AT358037B (de) 1980-08-11
GB1591723A (en) 1981-06-24
AU514676B2 (en) 1981-02-19
AU2912577A (en) 1979-04-05
IE45692L (en) 1978-04-05
GR71677B (fr) 1983-06-21
IL53013A (en) 1981-09-13
FR2367065B1 (fr) 1980-10-10
NL7710394A (nl) 1978-04-07
IE45692B1 (en) 1982-10-20
ZA775698B (en) 1978-05-30
IL53013A0 (en) 1977-11-30
ATA648777A (de) 1980-01-15
PT67048B (de) 1979-02-16
NO773125L (no) 1978-04-06
JPS5350177A (en) 1978-05-08
CH607585A5 (en) 1978-09-15
DK402877A (da) 1978-04-06
FR2367065A1 (fr) 1978-05-05
SE7710250L (sv) 1978-04-06
NZ185267A (en) 1979-07-11
BE858867A (fr) 1978-03-20
PT67048A (de) 1977-10-01
DE2740678A1 (de) 1978-04-06
FI772681A (fi) 1978-04-06
ES462389A1 (es) 1978-07-01

Similar Documents

Publication Publication Date Title
CA1134828A (fr) Derives de la pyridine
CA1124241A (fr) Aminoalcools n-alkyles et leurs sels; methodes pour les preparer, et compositions pharmaceutiques contenant ces substances
US4265894A (en) Piperazine derivatives
CA1067077A (fr) Procede pour la fabrication de derives a substituants cycliques du 1-amino-2-propanol
HU193161B (en) Process for preparing new n-alkyl-norscopines
US4559349A (en) Carboxamides
CA1041513A (fr) AMIDES D'ACIDE N-((PHENYLALCOYL)-1 PIPERIDYL-4)-N-(.alpha.-PYRIDYL) CARBONIQUE ET LEURS SELS ACIDES D'ADDITION
CA1247126A (fr) Derives d'acide phenoxyalcoylcarboxylique
CA1130805A (fr) Procede industriel d'obtention de derives de la pyrid (2,1-b) quinazoline
US4210653A (en) Pyridyloxypropanolamines
CA1105021A (fr) Traduction non-disponible
US5430033A (en) Piperazine derivatives
CA1202636A (fr) Phenylalcoylamines; preparation et utilisation comme compositions pharmaceutiques
CA1233828A (fr) Imidazoles substitues
CA1074799A (fr) Production d'alkoxypyridine carboxamides a substitution des bases
GB2040287A (en) 6-alkyl-1,2-dihydro-2-oxonicotinic acids and esters
GB2068373A (en) Cyclohexene derivatives
CA1050032A (fr) Procede de fabrication des animes
CA1193266A (fr) Benzamides derives, procede de preparation, composes pharmaceutiques les contenant
EP0009075A1 (fr) Pyridyloxypropanolamines et leurs esters, leur procédé de préparation et les compositions pharmaceutiques les contenant
CA1171085A (fr) Cyclopropylmethyl-piperazines, methode de preparation et utilisation dans des agents therapeutiques
CA2071940A1 (fr) Derives de la piperazine
US3862159A (en) 5-(haloalkyl) picolinic acid and derivatives
CA1152087A (fr) Furannes aryles, et methode pour les preparer
WO1984001945A1 (fr) Derives de phenoxyaminopropanol

Legal Events

Date Code Title Description
MKEX Expiry