AT358037B - METHOD FOR PRODUCING NEW 1-AMINO-2-HYDROXY-3-HETEROCYCLYLOXY PROPANES AND THEIR SALTS - Google Patents

METHOD FOR PRODUCING NEW 1-AMINO-2-HYDROXY-3-HETEROCYCLYLOXY PROPANES AND THEIR SALTS

Info

Publication number
AT358037B
AT358037B AT648777A AT648777A AT358037B AT 358037 B AT358037 B AT 358037B AT 648777 A AT648777 A AT 648777A AT 648777 A AT648777 A AT 648777A AT 358037 B AT358037 B AT 358037B
Authority
AT
Austria
Prior art keywords
propanes
heterocyclyloxy
hydroxy
salts
amino
Prior art date
Application number
AT648777A
Other languages
German (de)
Other versions
ATA648777A (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Priority to AT337979A priority Critical patent/AT358586B/en
Priority to AT338179A priority patent/AT360021B/en
Priority to AT338079A priority patent/AT358042B/en
Publication of ATA648777A publication Critical patent/ATA648777A/en
Application granted granted Critical
Publication of AT358037B publication Critical patent/AT358037B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/69Two or more oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • C07D213/85Nitriles in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/18Oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT648777A 1976-10-05 1977-09-09 METHOD FOR PRODUCING NEW 1-AMINO-2-HYDROXY-3-HETEROCYCLYLOXY PROPANES AND THEIR SALTS AT358037B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AT337979A AT358586B (en) 1976-10-05 1979-05-07 METHOD FOR PRODUCING NEW 1-AMINO-2-HYDROXY-3-HETEROCYCLYLOXY PROPANES AND THEIR SALTS
AT338179A AT360021B (en) 1976-10-05 1979-05-07 METHOD FOR PRODUCING NEW 1-AMINO-2-HYDROXY-3-HETEROCYCLYLOXY PROPANES AND THEIR SALTS
AT338079A AT358042B (en) 1976-10-05 1979-05-07 METHOD FOR PRODUCING NEW 1-AMINO-2-HYDROXY-3-HETEROCYCLYLOXY PROPANES AND THEIR SALTS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1263576A CH607585A5 (en) 1976-10-05 1976-10-05 Process for the preparation of 2-[3'-(2-(3,4-dimethoxy-phenyl)ethylamino)-2'-hydroxypropoxy]-3-cyanop yridine

Publications (2)

Publication Number Publication Date
ATA648777A ATA648777A (en) 1980-01-15
AT358037B true AT358037B (en) 1980-08-11

Family

ID=4384944

Family Applications (1)

Application Number Title Priority Date Filing Date
AT648777A AT358037B (en) 1976-10-05 1977-09-09 METHOD FOR PRODUCING NEW 1-AMINO-2-HYDROXY-3-HETEROCYCLYLOXY PROPANES AND THEIR SALTS

Country Status (21)

Country Link
JP (1) JPS5350177A (en)
AT (1) AT358037B (en)
AU (1) AU514676B2 (en)
BE (1) BE858867A (en)
CA (1) CA1105021A (en)
CH (1) CH607585A5 (en)
DE (1) DE2740678A1 (en)
DK (1) DK402877A (en)
ES (1) ES462389A1 (en)
FI (1) FI772681A (en)
FR (1) FR2367065A1 (en)
GB (1) GB1591723A (en)
GR (1) GR71677B (en)
IE (1) IE45692B1 (en)
IL (1) IL53013A (en)
NL (1) NL7710394A (en)
NO (1) NO773125L (en)
NZ (1) NZ185267A (en)
PT (1) PT67048B (en)
SE (1) SE7710250L (en)
ZA (1) ZA775698B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208416A (en) * 1978-06-27 1980-06-17 Merck & Co., Inc. N-Aralkyl containing cyanopyridines
US4210653A (en) * 1978-06-27 1980-07-01 Merck & Co., Inc. Pyridyloxypropanolamines
DK267779A (en) * 1978-06-27 1979-12-28 Merck & Co Inc PROCEDURE FOR THE PREPARATION OF N-ARALKYLAMINO-PROPOXYCYANOPYRIDINES
GB8510146D0 (en) * 1985-04-20 1985-05-30 Smith Kline French Lab Chemical compounds & processes
DE3776011D1 (en) * 1986-06-30 1992-02-27 Toyo Jozo Kk 2-SUBSTITUTED ALKOXY-3-SUBSTITUTED PYRAZINE.
AU1580001A (en) * 1999-11-15 2001-05-30 Eli Lilly And Company Process for the preparation of aryloxy propanolamines

Also Published As

Publication number Publication date
SE7710250L (en) 1978-04-06
CH607585A5 (en) 1978-09-15
AU514676B2 (en) 1981-02-19
PT67048B (en) 1979-02-16
IE45692B1 (en) 1982-10-20
NZ185267A (en) 1979-07-11
ATA648777A (en) 1980-01-15
FR2367065B1 (en) 1980-10-10
FI772681A (en) 1978-04-06
CA1105021A (en) 1981-07-14
GR71677B (en) 1983-06-21
JPS5350177A (en) 1978-05-08
PT67048A (en) 1977-10-01
ES462389A1 (en) 1978-07-01
DE2740678A1 (en) 1978-04-06
NO773125L (en) 1978-04-06
ZA775698B (en) 1978-05-30
FR2367065A1 (en) 1978-05-05
NL7710394A (en) 1978-04-07
IL53013A (en) 1981-09-13
DK402877A (en) 1978-04-06
IL53013A0 (en) 1977-11-30
BE858867A (en) 1978-03-20
GB1591723A (en) 1981-06-24
AU2912577A (en) 1979-04-05
IE45692L (en) 1978-04-05

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Legal Events

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ELJ Ceased due to non-payment of the annual fee