AT354425B - Verfahren zur herstellung von neuen n-(3- trifluormethylphenyl)-anthranilsaeurealkylestern - Google Patents

Verfahren zur herstellung von neuen n-(3- trifluormethylphenyl)-anthranilsaeurealkylestern

Info

Publication number
AT354425B
AT354425B AT881577A AT881577A AT354425B AT 354425 B AT354425 B AT 354425B AT 881577 A AT881577 A AT 881577A AT 881577 A AT881577 A AT 881577A AT 354425 B AT354425 B AT 354425B
Authority
AT
Austria
Prior art keywords
trifluormethylphenyl
alkyl esters
acid alkyl
producing new
anthranile
Prior art date
Application number
AT881577A
Other languages
English (en)
Other versions
ATA881577A (de
Inventor
Hideo Kato
Original Assignee
Hokuriku Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Pharmaceutical filed Critical Hokuriku Pharmaceutical
Publication of ATA881577A publication Critical patent/ATA881577A/de
Application granted granted Critical
Publication of AT354425B publication Critical patent/AT354425B/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245Amino benzoic acid types, e.g. procaine, novocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/56Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in ortho-position
    • C07C229/58Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in ortho-position having the nitrogen atom of at least one of the amino groups further bound to a carbon atom of a six-membered aromatic ring, e.g. N-phenyl-anthranilic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT881577A 1977-02-26 1977-12-09 Verfahren zur herstellung von neuen n-(3- trifluormethylphenyl)-anthranilsaeurealkylestern AT354425B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1978877A JPS53105445A (en) 1977-02-26 1977-02-26 Nn*33trifluoromethylphenyl* anthranylate alklyester derivative and process for preparing same

Publications (2)

Publication Number Publication Date
ATA881577A ATA881577A (de) 1979-06-15
AT354425B true AT354425B (de) 1980-01-10

Family

ID=12009067

Family Applications (1)

Application Number Title Priority Date Filing Date
AT881577A AT354425B (de) 1977-02-26 1977-12-09 Verfahren zur herstellung von neuen n-(3- trifluormethylphenyl)-anthranilsaeurealkylestern

Country Status (9)

Country Link
US (1) US4198431A (de)
JP (1) JPS53105445A (de)
AT (1) AT354425B (de)
BE (1) BE861852A (de)
CH (1) CH633522A5 (de)
DE (1) DE2754654C2 (de)
FR (1) FR2411825A1 (de)
GB (1) GB1595939A (de)
NL (1) NL186002C (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53105445A (en) * 1977-02-26 1978-09-13 Hokuriku Pharmaceutical Nn*33trifluoromethylphenyl* anthranylate alklyester derivative and process for preparing same
IT1113331B (it) * 1979-03-27 1986-01-20 Neopharmed Spa Esteri della salicilammide con attivita' terapeutica,procedimento per la loro preparazione e relative composizioni farmaceutiche
DE3811119C1 (de) * 1988-03-31 1989-10-12 Merckle Gmbh, 7902 Blaubeuren, De
US7632866B2 (en) 2002-10-21 2009-12-15 Ramot At Tel Aviv University Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators
EP2203411B1 (de) 2007-09-20 2016-01-06 Ramot at Tel-Aviv University Ltd. N-phenylanthranilsäurederivate und anwendungen davon
WO2009037705A2 (en) * 2007-09-20 2009-03-26 Ramot At Tel Aviv University Ltd. Esters of n-phenylanthranilic acid for use in the treatment of cancer and inflammation

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3144387A (en) * 1961-06-30 1964-08-11 Parke Davis & Co Anti-inflammatory compositions
FR2948M (fr) * 1962-09-18 1964-11-23 Parke Davis & Co Nouveaux médicaments, notamment anti-inflammatoires, dérivés de l'acide anthranilique.
US3413339A (en) * 1964-06-18 1968-11-26 Parke Davis & Co Amine compounds and methods for their production
US3558690A (en) * 1965-04-08 1971-01-26 Gelgy Chemical Corp Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation
US3767811A (en) * 1967-04-10 1973-10-23 Schering Corp Glyceryl n substituted phenyl anthranilates in the treatment of inflammation
US3511872A (en) * 1967-04-10 1970-05-12 Schering Corp Glyceryl-n-(substituted phenyl) anthranilates
DE1939112C3 (de) * 1969-08-01 1975-03-06 Troponwerke Dinklage & Co, 5000 Koeln Ester der N-(3-Trifluormethylphenyl) -anthranilsäure, Verfahren zu ihrer Herstellung und pharmakologisch wirksame Zubereitungen derselben
FR2145421B1 (de) * 1971-07-15 1974-09-06 Crt Societe
US4029815A (en) * 1975-04-30 1977-06-14 Schering Corporation Anti-diarrheal anthranilic acids
JPS53105445A (en) * 1977-02-26 1978-09-13 Hokuriku Pharmaceutical Nn*33trifluoromethylphenyl* anthranylate alklyester derivative and process for preparing same
US4143151A (en) * 1978-07-03 1979-03-06 The Dow Chemical Company Method for treating hyperglycemia in mammals using arylamino benzoic acids
JPH1190475A (ja) * 1997-09-25 1999-04-06 Sekisui Plastics Co Ltd 微生物担体

Also Published As

Publication number Publication date
FR2411825B1 (de) 1980-10-17
US4198431A (en) 1980-04-15
FR2411825A1 (fr) 1979-07-13
CH633522A5 (de) 1982-12-15
NL186002B (nl) 1990-04-02
GB1595939A (en) 1981-08-19
NL186002C (nl) 1990-09-03
ATA881577A (de) 1979-06-15
DE2754654A1 (de) 1979-06-13
NL7800048A (nl) 1979-07-04
DE2754654C2 (de) 1984-11-08
BE861852A (fr) 1978-03-31
JPS53105445A (en) 1978-09-13

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Legal Events

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ELJ Ceased due to non-payment of the annual fee