GB1001355A - Substituted anthranilic acid esters - Google Patents
Substituted anthranilic acid estersInfo
- Publication number
- GB1001355A GB1001355A GB36647/63A GB3664763A GB1001355A GB 1001355 A GB1001355 A GB 1001355A GB 36647/63 A GB36647/63 A GB 36647/63A GB 3664763 A GB3664763 A GB 3664763A GB 1001355 A GB1001355 A GB 1001355A
- Authority
- GB
- United Kingdom
- Prior art keywords
- reaction
- acid
- compounds
- anthranilic acid
- trifluoromethylphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises compounds of general formula <FORM:1001355/C2/1> wherein lower alkyl radicals have 1-7 carbon atoms; and their preparation as exemplified, comprising (1) reaction of corresponding anthranilic acids or their reactive derivatives with esterifying agents, or (2) reaction of 2-halo or amino-benzoic acid esters with, respectively, 3-amino or halo-trifluoromethylbenzenes. N - (3 - Trifluoromethylphenyl)anthranilic acid chloride is prepared from the acid with thionyl chloride; on reaction with the sodium salt it yields the acid anhydride. N - (3 - Trifluoromethylphenyl)anthranilic acid and its salts are obtainable by hydrolysis of the lower alkyl esters. Pharmaceutical compositions comprise compounds I with diluents and excipients. Oral (tablets, pills, sachets, powders, capsules) and parenteral (solutions, suspensions) administration is mentioned. The compounds have anti-inflammatory, hypocholesteremic and anthelmintic activity.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US22451962A | 1962-09-18 | 1962-09-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1001355A true GB1001355A (en) | 1965-08-18 |
Family
ID=22841047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB36647/63A Expired GB1001355A (en) | 1962-09-18 | 1963-09-17 | Substituted anthranilic acid esters |
Country Status (2)
Country | Link |
---|---|
FR (1) | FR2948M (en) |
GB (1) | GB1001355A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53105445A (en) * | 1977-02-26 | 1978-09-13 | Hokuriku Pharmaceutical | Nn*33trifluoromethylphenyl* anthranylate alklyester derivative and process for preparing same |
-
1963
- 1963-09-17 FR FR947775A patent/FR2948M/en active Active
- 1963-09-17 GB GB36647/63A patent/GB1001355A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2948M (en) | 1964-11-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GEP19960467B (en) | Method of producing derivatives of quinoline or their pharmaceutically acceptable esters or acid-additive salts | |
US3755603A (en) | Biphenylyloxyacetic acids in pharmaceutical compositions | |
ES461399A1 (en) | Epinine esters and pharmaceutical compositions thereof | |
GB1285400A (en) | Esters of substituted anthranilic acid | |
GB1531963A (en) | Pyrido(1,2alpha)pyrimidine derivatives | |
GB1308028A (en) | Thiazolylbenzoic acid derivatives and a process for their manufactur | |
GB1001355A (en) | Substituted anthranilic acid esters | |
GB1530074A (en) | Rho-acetamidophenol derivatives the preparation thereof and the use of such derivatives as therapeutic agents | |
GB1029915A (en) | Substituted 1,5-diarylpyrroles | |
GB1194505A (en) | Piperidinol Derivatives and Process for Preparing Them | |
GB1001356A (en) | Substituted anthranilic acid esters | |
GB993545A (en) | Substituted 1,5-diarylpyrroles | |
GB1322112A (en) | 3,4,5-trimethoxybenzoic acid derivatives and their uses | |
ES435604A1 (en) | Indolylacetylamino acid derivatives, process for their preparation, and pharmaceutical compositions | |
GB1416018A (en) | Therapeutic compositions and method of treatment | |
GB1299201A (en) | Medicaments derived from thiazolidine carboxylic acid | |
GB1112909A (en) | Ergoline derivatives | |
GB1319197A (en) | 3,4,5-trisubstituted benzoic acid derivatives and their uses | |
GB1448758A (en) | Thiazole derivatives | |
GB1114692A (en) | Improvements in or relating to phenthiazine derivatives | |
NL298015A (en) | ||
GB1116775A (en) | ªß-hydroxy-acrylic acid derivatives and process for their manufacture | |
GB1185267A (en) | Improvements in or relating to New Tetracycline Derivatives, a Process for their Preparation and a Therapeutic Composition obtained thereby | |
GB1313838A (en) | 3,4,5-trialkoxybenzoic acid derivatives and their uses | |
GB1461789A (en) | 3-substituted propanoic acid derivatives |