FR2411825A1 - N-(trifluoromethyl-3-phenyl) anthranilate d'alcoyle, utilise comme agent anti-inflammatoire - Google Patents

N-(trifluoromethyl-3-phenyl) anthranilate d'alcoyle, utilise comme agent anti-inflammatoire

Info

Publication number
FR2411825A1
FR2411825A1 FR7737523A FR7737523A FR2411825A1 FR 2411825 A1 FR2411825 A1 FR 2411825A1 FR 7737523 A FR7737523 A FR 7737523A FR 7737523 A FR7737523 A FR 7737523A FR 2411825 A1 FR2411825 A1 FR 2411825A1
Authority
FR
France
Prior art keywords
trifluoromethyl
phenyl
inflammatory agent
anthranilate
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7737523A
Other languages
English (en)
Other versions
FR2411825B1 (fr
Inventor
Hideo Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Japan Co Ltd
Original Assignee
Hokuriku Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Pharmaceutical Co Ltd filed Critical Hokuriku Pharmaceutical Co Ltd
Publication of FR2411825A1 publication Critical patent/FR2411825A1/fr
Application granted granted Critical
Publication of FR2411825B1 publication Critical patent/FR2411825B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/56—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in ortho-position
    • C07C229/58—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in ortho-position having the nitrogen atom of at least one of the amino groups further bound to a carbon atom of a six-membered aromatic ring, e.g. N-phenyl-anthranilic acids

Abstract

LA PRESENTE INVENTION CONCERNE UN N-(TRIFLUOROMETHYL-3-PHENYL) ANTHRANILATE D'ALCOYLE. L'ESTER D'ACIDE N-(TRIFLUOROMETHYL-3-PHENYL) ANTHRANILIQUE EST REPRESENTE PAR LA FORMULE: (CF DESSIN DANS BOPI) DANS LAQUELLE R REPRESENTE UN GROUPE ALCOYLE PRESENTANT DE 4 A 8 ATOMES DE CARBONE. LA PRESENTE INVENTION EST UTILISEE COMME AGENT ANTI-INFLAMMATOIRE.
FR7737523A 1977-02-26 1977-12-13 N-(trifluoromethyl-3-phenyl) anthranilate d'alcoyle, utilise comme agent anti-inflammatoire Granted FR2411825A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1978877A JPS53105445A (en) 1977-02-26 1977-02-26 Nn*33trifluoromethylphenyl* anthranylate alklyester derivative and process for preparing same

Publications (2)

Publication Number Publication Date
FR2411825A1 true FR2411825A1 (fr) 1979-07-13
FR2411825B1 FR2411825B1 (fr) 1980-10-17

Family

ID=12009067

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7737523A Granted FR2411825A1 (fr) 1977-02-26 1977-12-13 N-(trifluoromethyl-3-phenyl) anthranilate d'alcoyle, utilise comme agent anti-inflammatoire

Country Status (9)

Country Link
US (1) US4198431A (fr)
JP (1) JPS53105445A (fr)
AT (1) AT354425B (fr)
BE (1) BE861852A (fr)
CH (1) CH633522A5 (fr)
DE (1) DE2754654C2 (fr)
FR (1) FR2411825A1 (fr)
GB (1) GB1595939A (fr)
NL (1) NL186002C (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009037705A2 (fr) * 2007-09-20 2009-03-26 Ramot At Tel Aviv University Ltd. Méthodes et compositions utiles pour le traitement du cancer et de l'inflammation
US8278357B2 (en) 2002-10-21 2012-10-02 Ramot At Tel-Aviv University Ltd. Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators
US8765815B2 (en) 2007-09-20 2014-07-01 Ramot At Tel-Aviv University Ltd. N-phenyl anthranilic acid derivatives and uses thereof

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53105445A (en) * 1977-02-26 1978-09-13 Hokuriku Pharmaceutical Nn*33trifluoromethylphenyl* anthranylate alklyester derivative and process for preparing same
IT1113331B (it) * 1979-03-27 1986-01-20 Neopharmed Spa Esteri della salicilammide con attivita' terapeutica,procedimento per la loro preparazione e relative composizioni farmaceutiche
DE3811119C1 (fr) * 1988-03-31 1989-10-12 Merckle Gmbh, 7902 Blaubeuren, De

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7472M (fr) * 1967-04-10 1969-12-01
FR2060069A1 (fr) * 1969-08-01 1971-06-11 Troponwerke Dinklage & Co
JPH1190475A (ja) * 1997-09-25 1999-04-06 Sekisui Plastics Co Ltd 微生物担体

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3144387A (en) * 1961-06-30 1964-08-11 Parke Davis & Co Anti-inflammatory compositions
FR2948M (fr) * 1962-09-18 1964-11-23 Parke Davis & Co Nouveaux médicaments, notamment anti-inflammatoires, dérivés de l'acide anthranilique.
US3413339A (en) * 1964-06-18 1968-11-26 Parke Davis & Co Amine compounds and methods for their production
US3558690A (en) * 1965-04-08 1971-01-26 Gelgy Chemical Corp Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation
US3767811A (en) * 1967-04-10 1973-10-23 Schering Corp Glyceryl n substituted phenyl anthranilates in the treatment of inflammation
FR2145421B1 (fr) * 1971-07-15 1974-09-06 Crt Societe
US4029815A (en) * 1975-04-30 1977-06-14 Schering Corporation Anti-diarrheal anthranilic acids
JPS53105445A (en) * 1977-02-26 1978-09-13 Hokuriku Pharmaceutical Nn*33trifluoromethylphenyl* anthranylate alklyester derivative and process for preparing same
US4143151A (en) * 1978-07-03 1979-03-06 The Dow Chemical Company Method for treating hyperglycemia in mammals using arylamino benzoic acids

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7472M (fr) * 1967-04-10 1969-12-01
FR2060069A1 (fr) * 1969-08-01 1971-06-11 Troponwerke Dinklage & Co
JPH1190475A (ja) * 1997-09-25 1999-04-06 Sekisui Plastics Co Ltd 微生物担体

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8278357B2 (en) 2002-10-21 2012-10-02 Ramot At Tel-Aviv University Ltd. Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators
US8618169B2 (en) 2002-10-21 2013-12-31 Ramot At Tel-Aviv University Ltd. Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators
WO2009037705A2 (fr) * 2007-09-20 2009-03-26 Ramot At Tel Aviv University Ltd. Méthodes et compositions utiles pour le traitement du cancer et de l'inflammation
WO2009037705A3 (fr) * 2007-09-20 2009-07-09 Univ Ramot Méthodes et compositions utiles pour le traitement du cancer et de l'inflammation
US8765815B2 (en) 2007-09-20 2014-07-01 Ramot At Tel-Aviv University Ltd. N-phenyl anthranilic acid derivatives and uses thereof
US9403756B2 (en) 2007-09-20 2016-08-02 Ramot At Tel-Aviv University Ltd. N-phenyl anthranilic acid derivatives and uses thereof

Also Published As

Publication number Publication date
DE2754654C2 (de) 1984-11-08
ATA881577A (de) 1979-06-15
GB1595939A (en) 1981-08-19
CH633522A5 (de) 1982-12-15
FR2411825B1 (fr) 1980-10-17
BE861852A (fr) 1978-03-31
NL186002B (nl) 1990-04-02
DE2754654A1 (de) 1979-06-13
US4198431A (en) 1980-04-15
JPS53105445A (en) 1978-09-13
NL186002C (nl) 1990-09-03
AT354425B (de) 1980-01-10
NL7800048A (nl) 1979-07-04

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Legal Events

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ST Notification of lapse