AT351678B - Verfahren zur herstellung von neuen estern von salzen der 6-(1-sulfatoaethyl)-7-oxo-1- azabicyclo(3,2,0)hept-2-en-2-carbonsaeure - Google Patents

Verfahren zur herstellung von neuen estern von salzen der 6-(1-sulfatoaethyl)-7-oxo-1- azabicyclo(3,2,0)hept-2-en-2-carbonsaeure

Info

Publication number
AT351678B
AT351678B AT592177A AT592177A AT351678B AT 351678 B AT351678 B AT 351678B AT 592177 A AT592177 A AT 592177A AT 592177 A AT592177 A AT 592177A AT 351678 B AT351678 B AT 351678B
Authority
AT
Austria
Prior art keywords
sulfatoaethyl
azabicyclo
hept
oxo
salts
Prior art date
Application number
AT592177A
Other languages
German (de)
English (en)
Other versions
ATA592177A (de
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of ATA592177A publication Critical patent/ATA592177A/de
Application granted granted Critical
Publication of AT351678B publication Critical patent/AT351678B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/54Quaternary phosphonium compounds
    • C07F9/5456Arylalkanephosphonium compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT592177A 1976-08-17 1977-08-16 Verfahren zur herstellung von neuen estern von salzen der 6-(1-sulfatoaethyl)-7-oxo-1- azabicyclo(3,2,0)hept-2-en-2-carbonsaeure AT351678B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB34106/76A GB1531141A (en) 1976-08-17 1976-08-17 Beta-lactam antibiotics

Publications (2)

Publication Number Publication Date
ATA592177A ATA592177A (de) 1979-01-15
AT351678B true AT351678B (de) 1979-08-10

Family

ID=10361448

Family Applications (1)

Application Number Title Priority Date Filing Date
AT592177A AT351678B (de) 1976-08-17 1977-08-16 Verfahren zur herstellung von neuen estern von salzen der 6-(1-sulfatoaethyl)-7-oxo-1- azabicyclo(3,2,0)hept-2-en-2-carbonsaeure

Country Status (19)

Country Link
JP (1) JPS5323995A (sv)
AT (1) AT351678B (sv)
AU (1) AU518375B2 (sv)
BE (1) BE857781A (sv)
CA (1) CA1104139A (sv)
CH (1) CH639664A5 (sv)
DE (1) DE2736482A1 (sv)
DK (1) DK364177A (sv)
ES (1) ES461691A1 (sv)
FI (1) FI772432A7 (sv)
FR (2) FR2362142A1 (sv)
GB (1) GB1531141A (sv)
IE (1) IE45559B1 (sv)
IL (1) IL52638A (sv)
NL (1) NL7709007A (sv)
NZ (1) NZ184808A (sv)
PT (1) PT66882B (sv)
SE (1) SE7709071L (sv)
ZA (1) ZA774703B (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2862419D1 (en) * 1977-11-12 1984-07-26 Beecham Group Plc Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates
EP0004132A1 (en) * 1978-03-04 1979-09-19 Beecham Group Plc Esters of beta-lactam antibiotics, a process for their preparation pharmaceutical compositions containing them and the compounds for use as antibacterial agents
US4446146A (en) * 1978-07-26 1984-05-01 Beecham Group Limited β-Lactam containing compounds, their preparation and use
EP0007753B1 (en) * 1978-08-02 1982-08-25 Beecham Group Plc Beta-lactam antibacterial agents, a process for their preparation and pharmaceutical compositions containing them
US4530791A (en) * 1979-04-16 1985-07-23 Kowa Co., Ltd. β-Lactam antibiotics
EP0024832B1 (en) * 1979-08-10 1985-03-13 Beecham Group Plc Beta-lactam antibiotics, their preparation, pharmaceutical compositions containing them and their preparation
EP0044142A1 (en) * 1980-07-03 1982-01-20 Beecham Group Plc Process for the preparation of beta-lactam antibiotics
EP0057565A1 (en) * 1981-02-04 1982-08-11 Beecham Group Plc Beta-lactam antibiotics, their preparation and use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH633554A5 (en) * 1975-11-21 1982-12-15 Merck & Co Inc Process for the preparation of novel thienamycin derivatives.

Also Published As

Publication number Publication date
BE857781A (fr) 1978-02-13
FR2405260B1 (sv) 1980-10-31
CA1104139A (en) 1981-06-30
GB1531141A (en) 1978-11-01
FR2362142A1 (fr) 1978-03-17
ES461691A1 (es) 1978-06-01
DE2736482A1 (de) 1978-02-23
NZ184808A (en) 1980-04-28
SE7709071A0 (sv) 1978-02-17
AU2798677A (en) 1979-02-22
JPS5323995A (en) 1978-03-06
IL52638A (en) 1980-12-31
PT66882A (fr) 1977-09-01
ATA592177A (de) 1979-01-15
PT66882B (fr) 1979-01-24
FR2405260A1 (fr) 1979-05-04
AU518375B2 (en) 1981-10-01
NL7709007A (nl) 1978-02-21
IE45559B1 (en) 1982-09-22
IL52638A0 (en) 1977-10-31
CH639664A5 (en) 1983-11-30
FR2362142B1 (sv) 1981-11-06
FI772432A7 (fi) 1978-02-18
DK364177A (da) 1978-02-18
IE45559L (en) 1978-02-17
SE7709071L (sv) 1978-02-17
ZA774703B (en) 1978-06-28

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties