AT296503B - Verfahren zur Herstellung des neuen 7-(D-α-Aminophenylacetamido)-3-methyl-3-cephem-4-carbonsäure-Monohydrats (Cephalexinmonohydrats) - Google Patents
Verfahren zur Herstellung des neuen 7-(D-α-Aminophenylacetamido)-3-methyl-3-cephem-4-carbonsäure-Monohydrats (Cephalexinmonohydrats)Info
- Publication number
- AT296503B AT296503B AT343570A AT343570A AT296503B AT 296503 B AT296503 B AT 296503B AT 343570 A AT343570 A AT 343570A AT 343570 A AT343570 A AT 343570A AT 296503 B AT296503 B AT 296503B
- Authority
- AT
- Austria
- Prior art keywords
- monohydrate
- aminophenylacetamido
- cephem
- methyl
- preparation
- Prior art date
Links
- AVGYWQBCYZHHPN-DLFVXPSJSA-N O.N[C@@H](C(=O)NC1[C@@H]2N(C(=C(CS2)C)C(=O)O)C1=O)C1=CC=CC=C1 Chemical compound O.N[C@@H](C(=O)NC1[C@@H]2N(C(=C(CS2)C)C(=O)O)C1=O)C1=CC=CC=C1 AVGYWQBCYZHHPN-DLFVXPSJSA-N 0.000 title 1
- 229940047526 cephalexin monohydrate Drugs 0.000 title 1
- YGZIWEZFFBPCLN-UHFFFAOYSA-N n,3-bis(2-chloroethyl)-4-hydroperoxy-2-oxo-1,3,2$l^{5}-oxazaphosphinan-2-amine Chemical compound OOC1CCOP(=O)(NCCCl)N1CCCl YGZIWEZFFBPCLN-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Clamps And Clips (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81805769A | 1969-04-21 | 1969-04-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT296503B true AT296503B (de) | 1972-02-25 |
Family
ID=25224552
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT343570A AT296503B (de) | 1969-04-21 | 1970-04-15 | Verfahren zur Herstellung des neuen 7-(D-α-Aminophenylacetamido)-3-methyl-3-cephem-4-carbonsäure-Monohydrats (Cephalexinmonohydrats) |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US3502663A (de) |
| AT (1) | AT296503B (de) |
| BR (1) | BR6914873D0 (de) |
| CH (1) | CH529789A (de) |
| CS (1) | CS166256B2 (de) |
| ES (1) | ES378831A1 (de) |
| NO (1) | NO135067C (de) |
| PL (1) | PL80656B1 (de) |
| SE (1) | SE361044B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL149810B (nl) * | 1969-04-21 | 1976-06-15 | Lilly Co Eli | Werkwijze ter bereiding van een farmaceutisch preparaat door kristallijn cefalexine in een voor therapeutische toediening geschikte vorm te brengen, gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van voor bovengenoemde toepassing geschikt cefalexine. |
| GB1317159A (en) * | 1969-09-26 | 1973-05-16 | Glaxo Lab Ltd | Manufacture of cephalosporin compounds |
| IT1126544B (it) * | 1979-12-07 | 1986-05-21 | Dobfar Spa | Procedimento per la preparazione di derivati dell'acido 7-amino-desacetossi cefalosporanico |
| JPS60231683A (ja) * | 1984-05-02 | 1985-11-18 | Teijin Ltd | セフアロスポリン誘導体その製造法及びそれを有効成分とする抗菌剤 |
| US5278157A (en) * | 1989-07-10 | 1994-01-11 | Gema, S.A. | Stable cephradine hydrate |
| US5352782A (en) * | 1993-06-04 | 1994-10-04 | Eli Lilly And Company | Process for preparing crystalline β-lactam monohydrate |
| US5374719A (en) * | 1993-06-04 | 1994-12-20 | Eli Lilly And Company | Process for converting loracarbef dihydrate to loracarbef monohydrate |
| US5399686A (en) * | 1993-06-04 | 1995-03-21 | Eli Lilly And Company | Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate |
| US5580977A (en) * | 1995-03-01 | 1996-12-03 | Eli Lilly And Company | Process for preparing loracarbef monohydrate |
-
1969
- 1969-04-21 US US818057A patent/US3502663A/en not_active Expired - Lifetime
- 1969-12-08 BR BR214873/69A patent/BR6914873D0/pt unknown
-
1970
- 1970-04-10 CH CH537370A patent/CH529789A/de not_active IP Right Cessation
- 1970-04-15 AT AT343570A patent/AT296503B/de not_active IP Right Cessation
- 1970-04-20 ES ES378831A patent/ES378831A1/es not_active Expired
- 1970-04-20 SE SE05432/70A patent/SE361044B/xx unknown
- 1970-04-20 PL PL1970140132A patent/PL80656B1/pl unknown
- 1970-04-20 NO NO1493/70A patent/NO135067C/no unknown
- 1970-04-21 CS CS2693A patent/CS166256B2/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CS166256B2 (de) | 1976-02-27 |
| NO135067B (de) | 1976-10-25 |
| SE361044B (de) | 1973-10-15 |
| US3502663A (en) | 1970-03-24 |
| NO135067C (de) | 1977-02-02 |
| CH529789A (de) | 1972-10-31 |
| ES378831A1 (es) | 1973-01-16 |
| BR6914873D0 (pt) | 1973-03-08 |
| PL80656B1 (en) | 1975-08-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AT296504B (de) | Verfahren zur Herstellung des neuen 7-(D-α-Aminophenylacetamido)-3-methyl-3-cephem-4-carbonsäure-Monohydrats (Cephalexinmonohydrats) | |
| AT303259B (de) | Verfahren zur Herstellung von neuen 2-0-Acylsalicylsäurederivaten | |
| CH544774A (de) | Verfahren zur Herstellung von 7-(a-3-Acylureidophenyl-acetamido)- und 7-(a-3-Acylureidothienylacetamido)-cephalosporansäuren | |
| AT296503B (de) | Verfahren zur Herstellung des neuen 7-(D-α-Aminophenylacetamido)-3-methyl-3-cephem-4-carbonsäure-Monohydrats (Cephalexinmonohydrats) | |
| AT304762B (de) | Verfahren zur Herstellung von Cephalosporansäurederivaten | |
| CH544773A (de) | Verfahren zur Herstellung von Cephalosporansäure-Derivaten | |
| AT301026B (de) | Verfahren zur Herstellung von neuen Aminopenicillansäurederivaten | |
| CH525241A (de) | Verfahren zur Herstellung substituierter Cephem-4-carbonsäureester | |
| AT301534B (de) | Verfahren zur Herstellung von neuen [(Thernylidenamino)-oxyd]-alkylcarbonsäurederivaten | |
| AT301754B (de) | Verfahren zur Herstellung von 7-Aminocephalosporansäure | |
| AT295506B (de) | Verfahren zur Herstellung des neuen (-)threo-β-(4-Hydroxy-3-methoxyphenyl)-serins | |
| CH532614A (de) | Verfahren zur Herstellung von Derivaten der Cephalosporansäure bzw. Decephalosporansäure | |
| AT330157B (de) | Verfahren zur herstellung von neuen m-(2-aminoathyl)-benzoesaureestern | |
| AT300196B (de) | Verfahren zur Herstellung des neuen Erythromycyl-B-amins | |
| CH536321A (de) | Verfahren zur Herstellung von Cephalosporinantibiotica | |
| AT309676B (de) | Verfahren zur Herstellung von 7-Aminocephalosporansäure-Derivaten | |
| CH537947A (de) | Verfahren zur Herstellung neuer Cephalosporansäurederivate | |
| AT295759B (de) | Verfahren zur Herstellung des neuen Nα-Acetyl-2-O-methyltyrosin-oxytocins | |
| AT296337B (de) | Verfahren zur Herstellung von neuen Amidothionophosphorsäurephenylestern | |
| AT314734B (de) | Verfahren zur Herstellung von 7-Aminocephalosporansäure | |
| CH536358A (de) | Verfahren zur Herstellung des neuen Antibiotikums Largomycin | |
| CH547264A (de) | Verfahren zur herstellung von trihalogenmethylbenzosulfonsaeurehalogeniden. | |
| AT294842B (de) | Verfahren zur Herstellung des Chinoxalin-di-N-oxyd-aldehyds | |
| AT298692B (de) | Verfahren zur Herstellung des neuen 9α-Fluor-16-fluormethylen-prednisolon-21-önanthats | |
| AT315366B (de) | Verfahren zur Herstellung von Cephem-4-carbonsäureestern |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |