CH537947A - Verfahren zur Herstellung neuer Cephalosporansäurederivate - Google Patents

Verfahren zur Herstellung neuer Cephalosporansäurederivate

Info

Publication number
CH537947A
CH537947A CH1394370A CH1394370A CH537947A CH 537947 A CH537947 A CH 537947A CH 1394370 A CH1394370 A CH 1394370A CH 1394370 A CH1394370 A CH 1394370A CH 537947 A CH537947 A CH 537947A
Authority
CH
Switzerland
Prior art keywords
preparation
acid derivatives
cephalosporanic acid
new
new cephalosporanic
Prior art date
Application number
CH1394370A
Other languages
English (en)
Inventor
Murakami Masuro
Isaka Ichiro
Kashiwagi Teruya
Kawahara Norio
Nakano Kohzi
Murakami Keisuke
Morioka Motoo
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of CH537947A publication Critical patent/CH537947A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/32—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by an araliphatic carboxylic acid, which is substituted on the aliphatic radical by hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
CH1394370A 1969-09-22 1970-09-21 Verfahren zur Herstellung neuer Cephalosporansäurederivate CH537947A (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP7462669 1969-09-22
JP7810769 1969-10-02
JP10047969 1969-12-13

Publications (1)

Publication Number Publication Date
CH537947A true CH537947A (de) 1973-06-15

Family

ID=27301566

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1394370A CH537947A (de) 1969-09-22 1970-09-21 Verfahren zur Herstellung neuer Cephalosporansäurederivate

Country Status (4)

Country Link
CH (1) CH537947A (de)
DE (1) DE2046349A1 (de)
FR (1) FR2073304B1 (de)
GB (1) GB1292500A (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5248993B1 (de) * 1971-07-29 1977-12-14
YU37171B (en) * 1975-12-05 1984-08-31 Krka Novo Mesto Process for preparing 7-(d-2-amino-2-phenylacetamido)-3-methyl-3-cephem-4-carboxylic acid
CN116730808B (zh) * 2023-06-12 2024-11-08 重庆汉佩生物科技有限公司 头孢维星衍生物中间体的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1141293A (en) * 1964-12-23 1969-01-29 Glaxo Lab Ltd Cephemoic acids and derivatives thereof

Also Published As

Publication number Publication date
GB1292500A (en) 1972-10-11
FR2073304B1 (de) 1974-08-30
DE2046349A1 (de) 1971-04-01
FR2073304A1 (de) 1971-10-01

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Legal Events

Date Code Title Description
PL Patent ceased