AR221724A1 - Un procedimiento de preparacion de derivados de 1,2-y 1,3-(di-o-n-alquil)-3)o(2)-piperidino glicerol y sus sales de adicion de acidos farmaceuticamente aceptables,utiles como estimulantes no especificos de la inmunidad mediada celularmente - Google Patents
Un procedimiento de preparacion de derivados de 1,2-y 1,3-(di-o-n-alquil)-3)o(2)-piperidino glicerol y sus sales de adicion de acidos farmaceuticamente aceptables,utiles como estimulantes no especificos de la inmunidad mediada celularmenteInfo
- Publication number
- AR221724A1 AR221724A1 AR276517A AR27651779A AR221724A1 AR 221724 A1 AR221724 A1 AR 221724A1 AR 276517 A AR276517 A AR 276517A AR 27651779 A AR27651779 A AR 27651779A AR 221724 A1 AR221724 A1 AR 221724A1
- Authority
- AR
- Argentina
- Prior art keywords
- alquil
- piperidine
- immunity
- glycerol
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/44—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/906,260 US4173641A (en) | 1978-05-15 | 1978-05-15 | Di-O-n-alkyl glycerol derivatives as immune stimulants |
Publications (1)
Publication Number | Publication Date |
---|---|
AR221724A1 true AR221724A1 (es) | 1981-03-13 |
Family
ID=25422164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR276517A AR221724A1 (es) | 1978-05-15 | 1979-05-15 | Un procedimiento de preparacion de derivados de 1,2-y 1,3-(di-o-n-alquil)-3)o(2)-piperidino glicerol y sus sales de adicion de acidos farmaceuticamente aceptables,utiles como estimulantes no especificos de la inmunidad mediada celularmente |
Country Status (38)
Country | Link |
---|---|
US (1) | US4173641A (fr) |
JP (2) | JPS5924974B2 (fr) |
AR (1) | AR221724A1 (fr) |
AT (1) | AT372678B (fr) |
AU (1) | AU513771B2 (fr) |
BE (1) | BE876229A (fr) |
CA (1) | CA1105935A (fr) |
CH (1) | CH639939A5 (fr) |
DD (1) | DD144540A5 (fr) |
DE (1) | DE2919514C2 (fr) |
DK (1) | DK149946C (fr) |
EG (1) | EG15252A (fr) |
ES (1) | ES480565A1 (fr) |
FI (1) | FI69450C (fr) |
FR (1) | FR2426039A1 (fr) |
GB (1) | GB2021580B (fr) |
GR (1) | GR72419B (fr) |
GT (1) | GT197957869A (fr) |
HK (1) | HK13584A (fr) |
HU (1) | HU180283B (fr) |
IE (1) | IE48229B1 (fr) |
IL (1) | IL57268A (fr) |
IN (1) | IN150574B (fr) |
IT (1) | IT1115217B (fr) |
KE (1) | KE3354A (fr) |
LU (1) | LU81253A1 (fr) |
MY (1) | MY8500096A (fr) |
NL (1) | NL175524C (fr) |
NO (1) | NO151285C (fr) |
NZ (1) | NZ190444A (fr) |
PH (1) | PH15256A (fr) |
PL (1) | PL123910B1 (fr) |
PT (1) | PT69607A (fr) |
SE (1) | SE429966B (fr) |
SG (1) | SG65483G (fr) |
SU (1) | SU1122220A3 (fr) |
YU (1) | YU41156B (fr) |
ZA (1) | ZA792306B (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4312877A (en) * | 1979-07-09 | 1982-01-26 | Pfizer Inc. | 1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted piperidines, pharmaceutical compositions, thereof and use thereof |
US4255426A (en) * | 1979-07-09 | 1981-03-10 | Pfizer Inc. | 1-(2-Hydroxy-3-n-alkoxypropyl)-4-substituted-piperazines and piperidines |
US4395394A (en) * | 1979-10-26 | 1983-07-26 | Pfizer Inc. | Use of lipid amines formulated with fat or lipid emulsions as vaccine adjuvants |
US4310550A (en) * | 1979-10-26 | 1982-01-12 | Pfizer Inc. | Lipid amines formulated with fat or lipid emulsions as vaccine adjuvants |
JPS60105650A (ja) * | 1983-11-14 | 1985-06-11 | Ono Pharmaceut Co Ltd | グリセリン誘導体、その製造方法及びその誘導体を含有する薬剤 |
US4880626A (en) * | 1985-01-18 | 1989-11-14 | Mcmichael John | Immunotherapeutic methods and compositions for the treatment of diseases of viral origin, including acquired immune deficiency syndrome |
JPS62156230A (ja) * | 1985-12-27 | 1987-07-11 | Nippon Steel Corp | 帯状物の蛇行修正方法 |
US4842862A (en) * | 1986-07-03 | 1989-06-27 | International Minerals & Chemical Corp. | Immunostimulating agents |
ZA899436B (en) * | 1988-12-12 | 1990-08-29 | Ciba Geigy | Piperidine derivatives |
WO2005077963A1 (fr) * | 2004-01-16 | 2005-08-25 | Institut Superieur Agricole De Beauvais | DErivEs de saccharides et d'itols possEdant un groupement O-alkyle ou un groupement O-alkyle et un groupement O-n-butanoyle. Applications comme mEdicaments dans les pathologies prolifEratives tumorales ou bEnignes. |
CN102905763B (zh) * | 2009-12-23 | 2015-06-17 | 诺华股份有限公司 | 脂质、脂质组合物和使用它们的方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2738351A (en) * | 1952-08-02 | 1956-03-13 | Bristol Lab Inc | Substituted glycerol ethers |
US3432602A (en) * | 1967-12-20 | 1969-03-11 | Astra Ab | Oral alkyl glycerol ether improvement in radiation,radiomimetic,or cytostatic tumor therapies |
US3943173A (en) * | 1972-11-22 | 1976-03-09 | Smithkline Corporation | 3-Alkylamino- alpha-aminomethyl-4-hydroxybenzyl alcohols |
US4012528A (en) * | 1974-06-03 | 1977-03-15 | Smithkline Corporation | α-AMINOALKYL-3-(1,2-DIHYDROXYETHYL)-4-HYDROXY-BENZYL ALCOHOLS HAVING β-ADRENERGIC STIMULANT ACTIVITY |
US4069223A (en) * | 1977-05-02 | 1978-01-17 | G. D. Searle & Co. | 4-Aminomethyl-1-(3,3,3-triarylpropyl)-4-arylpiperidine and derivatives thereof |
US4166132A (en) * | 1977-08-18 | 1979-08-28 | Pfizer Inc. | Antiviral amine derivatives of glycerol and propanediols |
-
1978
- 1978-05-15 US US05/906,260 patent/US4173641A/en not_active Expired - Lifetime
-
1979
- 1979-03-12 DK DK102479A patent/DK149946C/da not_active IP Right Cessation
- 1979-03-13 IN IN173/DEL/79A patent/IN150574B/en unknown
- 1979-04-18 PH PH22379A patent/PH15256A/en unknown
- 1979-04-26 CH CH395479A patent/CH639939A5/fr not_active IP Right Cessation
- 1979-05-10 YU YU1094/79A patent/YU41156B/xx unknown
- 1979-05-11 AU AU47016/79A patent/AU513771B2/en not_active Ceased
- 1979-05-11 CA CA327,431A patent/CA1105935A/fr not_active Expired
- 1979-05-14 GB GB7916722A patent/GB2021580B/en not_active Expired
- 1979-05-14 LU LU81253A patent/LU81253A1/fr unknown
- 1979-05-14 SU SU792764751A patent/SU1122220A3/ru active
- 1979-05-14 HU HU79PI677A patent/HU180283B/hu not_active IP Right Cessation
- 1979-05-14 PT PT69607A patent/PT69607A/pt unknown
- 1979-05-14 FR FR7912175A patent/FR2426039A1/fr active Granted
- 1979-05-14 ZA ZA792306A patent/ZA792306B/xx unknown
- 1979-05-14 GR GR59080A patent/GR72419B/el unknown
- 1979-05-14 ES ES79480565A patent/ES480565A1/es not_active Expired
- 1979-05-14 IL IL57268A patent/IL57268A/xx unknown
- 1979-05-14 NO NO791604A patent/NO151285C/no unknown
- 1979-05-14 SE SE7904216A patent/SE429966B/sv not_active IP Right Cessation
- 1979-05-14 NZ NZ190444A patent/NZ190444A/xx unknown
- 1979-05-14 BE BE0/195142A patent/BE876229A/fr not_active IP Right Cessation
- 1979-05-14 AT AT0356179A patent/AT372678B/de not_active IP Right Cessation
- 1979-05-14 GT GT197957869A patent/GT197957869A/es unknown
- 1979-05-14 FI FI791531A patent/FI69450C/fi not_active IP Right Cessation
- 1979-05-14 PL PL1979215573A patent/PL123910B1/pl unknown
- 1979-05-14 IT IT22664/79A patent/IT1115217B/it active
- 1979-05-14 NL NLAANVRAGE7903769,A patent/NL175524C/xx active Search and Examination
- 1979-05-14 JP JP54059019A patent/JPS5924974B2/ja not_active Expired
- 1979-05-15 EG EG289/79A patent/EG15252A/xx active
- 1979-05-15 DE DE2919514A patent/DE2919514C2/de not_active Expired
- 1979-05-15 AR AR276517A patent/AR221724A1/es active
- 1979-05-15 DD DD79212895A patent/DD144540A5/de unknown
- 1979-08-08 IE IE938/79A patent/IE48229B1/en not_active IP Right Cessation
-
1982
- 1982-12-29 JP JP57235061A patent/JPS58131947A/ja active Granted
-
1983
- 1983-11-02 SG SG654/83A patent/SG65483G/en unknown
- 1983-11-22 KE KE3354A patent/KE3354A/xx unknown
-
1984
- 1984-02-16 HK HK135/84A patent/HK13584A/xx unknown
-
1985
- 1985-12-30 MY MY96/85A patent/MY8500096A/xx unknown
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