AR128119A1 - Método para producir n-alquilaminoácido y péptido que contiene n-alquilaminoácido - Google Patents
Método para producir n-alquilaminoácido y péptido que contiene n-alquilaminoácidoInfo
- Publication number
- AR128119A1 AR128119A1 ARP220103601A ARP220103601A AR128119A1 AR 128119 A1 AR128119 A1 AR 128119A1 AR P220103601 A ARP220103601 A AR P220103601A AR P220103601 A ARP220103601 A AR P220103601A AR 128119 A1 AR128119 A1 AR 128119A1
- Authority
- AR
- Argentina
- Prior art keywords
- ester
- acid
- alkylaminoacid
- monoalkylamino
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B61/00—Other general methods
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/062—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha- or omega-carboxy functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Analytical Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021214900 | 2021-12-28 | ||
| JP2022168608 | 2022-10-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR128119A1 true AR128119A1 (es) | 2024-03-27 |
Family
ID=86999039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP220103601A AR128119A1 (es) | 2021-12-28 | 2022-12-27 | Método para producir n-alquilaminoácido y péptido que contiene n-alquilaminoácido |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250197450A1 (https=) |
| EP (1) | EP4414374A4 (https=) |
| JP (2) | JP7430297B2 (https=) |
| KR (1) | KR102844018B1 (https=) |
| AR (1) | AR128119A1 (https=) |
| AU (1) | AU2022428318A1 (https=) |
| CA (1) | CA3237911A1 (https=) |
| IL (1) | IL312468A (https=) |
| MX (1) | MX2024008002A (https=) |
| TW (1) | TW202342495A (https=) |
| WO (1) | WO2023127869A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI787670B (zh) | 2011-12-28 | 2022-12-21 | 日商中外製藥股份有限公司 | 具有環狀部之胜肽化合物及其醫藥組成物 |
| WO2018225851A1 (ja) | 2017-06-09 | 2018-12-13 | 中外製薬株式会社 | N-置換アミノ酸を含むペプチドの合成方法 |
| EP3878836B1 (en) | 2018-11-07 | 2025-07-23 | Chugai Seiyaku Kabushiki Kaisha | O-substituted serine derivative production method |
| PE20221323A1 (es) | 2019-11-07 | 2022-09-09 | Chugai Pharmaceutical Co Ltd | Compuesto de peptidos ciclicos que tiene accion inhibidora de kras |
| TW202309065A (zh) | 2021-05-07 | 2023-03-01 | 日商中外製藥股份有限公司 | 包含n-取代胺基酸殘基之環狀化合物的製造方法 |
| CA3256645A1 (en) | 2022-05-06 | 2025-04-23 | Chugai Seiyaku Kabushiki Kaisha | CYCLIC COMPOUND HAVING A SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS |
| EP4596567A1 (en) | 2022-11-01 | 2025-08-06 | Chugai Seiyaku Kabushiki Kaisha | Method for removing dibenzofulvene or dibenzofulvene derivative |
| JPWO2024143514A1 (https=) | 2022-12-28 | 2024-07-04 | ||
| WO2025070753A1 (ja) | 2023-09-28 | 2025-04-03 | 中外製薬株式会社 | 混合酸無水物法を用いたペプチド化合物の製造方法 |
| CN121889409A (zh) | 2023-12-27 | 2026-04-17 | 中外制药株式会社 | 用于使用独立型缩合剂生产肽化合物的方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL1010063C2 (nl) | 1998-09-10 | 2000-03-13 | Holland Sweetener Co | Werkwijze voor de bereiding van neotaam. |
| JP7232758B2 (ja) | 2017-06-09 | 2023-03-06 | 中外製薬株式会社 | 膜透過性の高い環状ペプチド化合物、及びこれを含むライブラリ |
| WO2018225851A1 (ja) * | 2017-06-09 | 2018-12-13 | 中外製薬株式会社 | N-置換アミノ酸を含むペプチドの合成方法 |
| JP7568510B2 (ja) * | 2018-11-30 | 2024-10-16 | 中外製薬株式会社 | ペプチド化合物、またはアミド化合物の脱保護法および固相反応における脱樹脂方法、並びにペプチド化合物の製造方法 |
| WO2020122182A1 (ja) | 2018-12-12 | 2020-06-18 | 中外製薬株式会社 | 分子内水素結合可能な官能基を有するアミノ酸とそれらのアミノ酸を含むペプチド化合物、およびそれらの製造方法 |
| KR20210139366A (ko) | 2019-03-15 | 2021-11-22 | 추가이 세이야쿠 가부시키가이샤 | 방향족 아미노산 유도체의 제조 방법 |
| PE20221323A1 (es) * | 2019-11-07 | 2022-09-09 | Chugai Pharmaceutical Co Ltd | Compuesto de peptidos ciclicos que tiene accion inhibidora de kras |
-
2022
- 2022-12-27 MX MX2024008002A patent/MX2024008002A/es unknown
- 2022-12-27 EP EP22916092.4A patent/EP4414374A4/en active Pending
- 2022-12-27 CA CA3237911A patent/CA3237911A1/en active Pending
- 2022-12-27 AR ARP220103601A patent/AR128119A1/es unknown
- 2022-12-27 KR KR1020247023000A patent/KR102844018B1/ko active Active
- 2022-12-27 WO PCT/JP2022/048135 patent/WO2023127869A1/ja not_active Ceased
- 2022-12-27 AU AU2022428318A patent/AU2022428318A1/en active Pending
- 2022-12-27 US US18/723,993 patent/US20250197450A1/en active Pending
- 2022-12-27 TW TW111150100A patent/TW202342495A/zh unknown
- 2022-12-27 JP JP2023568520A patent/JP7430297B2/ja active Active
- 2022-12-27 IL IL312468A patent/IL312468A/en unknown
-
2024
- 2024-01-30 JP JP2024011686A patent/JP2024052694A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20240113971A (ko) | 2024-07-23 |
| EP4414374A1 (en) | 2024-08-14 |
| JPWO2023127869A1 (https=) | 2023-07-06 |
| IL312468A (en) | 2024-06-01 |
| WO2023127869A1 (ja) | 2023-07-06 |
| JP2024052694A (ja) | 2024-04-11 |
| EP4414374A4 (en) | 2025-11-19 |
| JP7430297B2 (ja) | 2024-02-09 |
| TW202342495A (zh) | 2023-11-01 |
| US20250197450A1 (en) | 2025-06-19 |
| CA3237911A1 (en) | 2023-07-06 |
| MX2024008002A (es) | 2024-07-12 |
| AU2022428318A1 (en) | 2024-05-16 |
| KR102844018B1 (ko) | 2025-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |