AR126447A1 - INHIBIDORES DE PI3Ka Y MÉTODOS DE USO DE LOS MISMOS - Google Patents
INHIBIDORES DE PI3Ka Y MÉTODOS DE USO DE LOS MISMOSInfo
- Publication number
- AR126447A1 AR126447A1 ARP220101841A ARP220101841A AR126447A1 AR 126447 A1 AR126447 A1 AR 126447A1 AR P220101841 A ARP220101841 A AR P220101841A AR P220101841 A ARP220101841 A AR P220101841A AR 126447 A1 AR126447 A1 AR 126447A1
- Authority
- AR
- Argentina
- Prior art keywords
- methods
- pi3ka
- compounds
- compositions
- disclosure
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000011664 signaling Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/20—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente divulgación se refiere a nuevos compuestos y composiciones farmacéuticas de los mismos, y a métodos para inhibir la actividad de las enzimas PI3Ka con los compuestos y composiciones de la divulgación. La presente divulgación se refiere, además, pero sin limitación, a métodos para tratar trastornos asociados con la señalización de PI3Ka con los compuestos y las composiciones de la divulgación.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163203220P | 2021-07-13 | 2021-07-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR126447A1 true AR126447A1 (es) | 2023-10-11 |
Family
ID=84919704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP220101841A AR126447A1 (es) | 2021-07-13 | 2022-07-13 | INHIBIDORES DE PI3Ka Y MÉTODOS DE USO DE LOS MISMOS |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP4370124A1 (es) |
| CN (1) | CN117881683A (es) |
| AR (1) | AR126447A1 (es) |
| AU (1) | AU2022311952A1 (es) |
| CA (1) | CA3225285A1 (es) |
| TW (1) | TW202317579A (es) |
| WO (1) | WO2023288242A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024051784A1 (zh) * | 2022-09-09 | 2024-03-14 | 上海璎黎药业有限公司 | 一种含氮杂环化合物、其药物组合物及应用 |
| WO2024097721A1 (en) | 2022-11-02 | 2024-05-10 | Petra Pharma Corporation | Targeting allosteric and orthosteric pockets of phosphoinositide 3-kinase (pi3k) for the treatment of disease |
| WO2024118810A1 (en) * | 2022-11-30 | 2024-06-06 | Protego Biopharma, Inc. | Cyclic pyrazole diamide ire1/xbp1s activators |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JO3368B1 (ar) * | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
| US10513524B2 (en) * | 2015-07-07 | 2019-12-24 | H. Lundbeck A/S | PDE9 inhibitors with imidazo triazinone backbone and imidazo pyrazinone backbone for treatment of peripheral diseases |
| KR20200090843A (ko) * | 2017-11-24 | 2020-07-29 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 6, 7-디히드로 피라졸로[1, 5-a]피라지논 유도체 및 그 의약 용도 |
| MX2021016133A (es) * | 2019-06-20 | 2022-07-19 | Univ Kentucky Res Found | Moduladores de la neddilación de cullina mediada por dcn1/2 de tipo pirazolo piridona farmacéuticamente activos. |
-
2022
- 2022-07-13 AR ARP220101841A patent/AR126447A1/es unknown
- 2022-07-13 CA CA3225285A patent/CA3225285A1/en active Pending
- 2022-07-13 WO PCT/US2022/073672 patent/WO2023288242A1/en active Application Filing
- 2022-07-13 AU AU2022311952A patent/AU2022311952A1/en active Pending
- 2022-07-13 TW TW111126296A patent/TW202317579A/zh unknown
- 2022-07-13 EP EP22843033.6A patent/EP4370124A1/en active Pending
- 2022-07-13 CN CN202280059784.8A patent/CN117881683A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2022311952A1 (en) | 2024-01-25 |
| TW202317579A (zh) | 2023-05-01 |
| WO2023288242A1 (en) | 2023-01-19 |
| CN117881683A (zh) | 2024-04-12 |
| CA3225285A1 (en) | 2023-01-19 |
| EP4370124A1 (en) | 2024-05-22 |
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