UY39588A - Pirazolotiazol carboxamidas y usos de estas como inhibidores de pdgfr - Google Patents

Pirazolotiazol carboxamidas y usos de estas como inhibidores de pdgfr

Info

Publication number
UY39588A
UY39588A UY0001039588A UY39588A UY39588A UY 39588 A UY39588 A UY 39588A UY 0001039588 A UY0001039588 A UY 0001039588A UY 39588 A UY39588 A UY 39588A UY 39588 A UY39588 A UY 39588A
Authority
UY
Uruguay
Prior art keywords
pyrazolothiazole
carboxamides
pdgfr inhibitors
compounds
formula
Prior art date
Application number
UY0001039588A
Other languages
English (en)
Inventor
David Bauman
Tianbao Lu
Bin Zhu
Van Nguyen
Marchello Cavitt
Michael J Hawkins
Zhijie Liu
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of UY39588A publication Critical patent/UY39588A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La descripción está dirigida a compuestos de la Fórmula (I) (I),y sales farmacéuticamente aceptables de estos. También se describen composiciones farmacéuticas que comprenden compuestos de la Fórmula (I), así como métodos para su uso y preparación.
UY0001039588A 2020-12-23 2021-12-23 Pirazolotiazol carboxamidas y usos de estas como inhibidores de pdgfr UY39588A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063130135P 2020-12-23 2020-12-23
US202163245587P 2021-09-17 2021-09-17

Publications (1)

Publication Number Publication Date
UY39588A true UY39588A (es) 2022-06-30

Family

ID=79831748

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001039588A UY39588A (es) 2020-12-23 2021-12-23 Pirazolotiazol carboxamidas y usos de estas como inhibidores de pdgfr

Country Status (8)

Country Link
US (1) US20240109917A1 (es)
EP (1) EP4267585A1 (es)
JP (1) JP2024500936A (es)
AU (1) AU2021405620A1 (es)
CA (1) CA3202944A1 (es)
TW (1) TW202241914A (es)
UY (1) UY39588A (es)
WO (1) WO2022136509A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023247596A1 (en) * 2022-06-22 2023-12-28 Actelion Pharmaceuticals Ltd Pyrazolothiazole carboxamides and their uses as pdgfr inhibitors
CN115724791A (zh) * 2022-10-10 2023-03-03 安徽金禾化学材料研究所有限公司 一种2-甲基-3-硝基-5-胺基吡啶的制备方法
WO2024104968A1 (en) * 2022-11-14 2024-05-23 Actelion Pharmaceuticals Ltd Pyrazolopyrrolopyridazines and their uses as pdgfr inhibitors
CN118407248B (zh) * 2024-07-02 2024-09-17 南通市嘉宇斯纺织集团有限公司 一种抗紫外线面料及其制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657744A (en) 1970-05-08 1972-04-25 Univ Minnesota Method for fixing prosthetic implants in a living body
US4733665C2 (en) 1985-11-07 2002-01-29 Expandable Grafts Partnership Expandable intraluminal graft and method and apparatus for implanting an expandable intraluminal graft
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
US5350395A (en) 1986-04-15 1994-09-27 Yock Paul G Angioplasty apparatus facilitating rapid exchanges
US5061273A (en) 1989-06-01 1991-10-29 Yock Paul G Angioplasty apparatus facilitating rapid exchanges
US5040548A (en) 1989-06-01 1991-08-20 Yock Paul G Angioplasty mehtod
US4748982A (en) 1987-01-06 1988-06-07 Advanced Cardiovascular Systems, Inc. Reinforced balloon dilatation catheter with slitted exchange sleeve and method
US4992445A (en) 1987-06-12 1991-02-12 American Cyanamid Co. Transdermal delivery of pharmaceuticals
US5001139A (en) 1987-06-12 1991-03-19 American Cyanamid Company Enchancers for the transdermal flux of nivadipine
CA1322628C (en) 1988-10-04 1993-10-05 Richard A. Schatz Expandable intraluminal graft
US5674278A (en) 1989-08-24 1997-10-07 Arterial Vascular Engineering, Inc. Endovascular support device
US6344053B1 (en) 1993-12-22 2002-02-05 Medtronic Ave, Inc. Endovascular support device and method
US5292331A (en) 1989-08-24 1994-03-08 Applied Vascular Engineering, Inc. Endovascular support device
US20140206682A1 (en) * 2011-09-01 2014-07-24 Novartis Pharmaceuticals Uk Limited Compounds and compositions as pdgfr kinase inhibitors
UY34305A (es) 2011-09-01 2013-04-30 Novartis Ag Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
JPWO2021117846A1 (es) * 2019-12-13 2021-06-17

Also Published As

Publication number Publication date
US20240109917A1 (en) 2024-04-04
TW202241914A (zh) 2022-11-01
JP2024500936A (ja) 2024-01-10
EP4267585A1 (en) 2023-11-01
CA3202944A1 (en) 2022-06-30
WO2022136509A1 (en) 2022-06-30
AU2021405620A1 (en) 2023-06-29

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