AR122736A1 - Anticuerpos que reconocen sortilina - Google Patents
Anticuerpos que reconocen sortilinaInfo
- Publication number
- AR122736A1 AR122736A1 ARP210101748A ARP210101748A AR122736A1 AR 122736 A1 AR122736 A1 AR 122736A1 AR P210101748 A ARP210101748 A AR P210101748A AR P210101748 A ARP210101748 A AR P210101748A AR 122736 A1 AR122736 A1 AR 122736A1
- Authority
- AR
- Argentina
- Prior art keywords
- sortilin
- antibodies recognizing
- antibodies
- delay
- changes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/286—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against neuromediator receptors, e.g. serotonin receptor, dopamine receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/71—Decreased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Abstract
La invención provee anticuerpos que se unen específicamente a sortilina. Los anticuerpos inhiben o demoran patologías asociadas con cambios en los niveles de progranulina y deterioro sintomático asociado.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US202063043481P | 2020-06-24 | 2020-06-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR122736A1 true AR122736A1 (es) | 2022-10-05 |
Family
ID=79281994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP210101748A AR122736A1 (es) | 2020-06-24 | 2021-06-24 | Anticuerpos que reconocen sortilina |
Country Status (12)
Country | Link |
---|---|
US (3) | US20230235048A1 (es) |
EP (1) | EP4171743A1 (es) |
JP (1) | JP2023533458A (es) |
KR (1) | KR20230026489A (es) |
CN (1) | CN116249717A (es) |
AR (1) | AR122736A1 (es) |
AU (1) | AU2021297540A1 (es) |
BR (1) | BR112022026508A2 (es) |
CA (1) | CA3183994A1 (es) |
IL (1) | IL299329A (es) |
TW (1) | TW202216773A (es) |
WO (1) | WO2021263279A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20230348588A1 (en) * | 2021-12-23 | 2023-11-02 | Prothena Biosciences Limited | Antibodies recognizing sortilin |
WO2023247754A1 (en) | 2022-06-23 | 2023-12-28 | Draupnir Bio Aps | Bifunctional molecules that selectively induce degradation of extracellular targets in lysosomes |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2007217765A1 (en) * | 2006-02-21 | 2007-08-30 | Nanogen, Inc. | Methods and compositions for analyte detection |
LT2954779T (lt) * | 2009-12-10 | 2019-05-27 | Regeneron Pharmaceuticals, Inc. | Pelės, gaminančios sunkiosios grandinės antikūnus |
CA2791658C (en) * | 2010-03-04 | 2019-10-01 | Macrogenics, Inc. | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
EP2844675B1 (en) * | 2012-05-02 | 2019-01-02 | Symphogen A/S | Humanized pan-her antibody compositions |
ES2899227T3 (es) * | 2015-04-07 | 2022-03-10 | Alector Llc | Anticuerpos anti sortilina y métodos de uso de los mismos |
-
2021
- 2021-06-23 IL IL299329A patent/IL299329A/en unknown
- 2021-06-23 JP JP2022579951A patent/JP2023533458A/ja active Pending
- 2021-06-23 EP EP21829181.3A patent/EP4171743A1/en active Pending
- 2021-06-23 AU AU2021297540A patent/AU2021297540A1/en active Pending
- 2021-06-23 US US18/011,764 patent/US20230235048A1/en active Pending
- 2021-06-23 WO PCT/US2021/070764 patent/WO2021263279A1/en unknown
- 2021-06-23 CN CN202180051773.0A patent/CN116249717A/zh active Pending
- 2021-06-23 BR BR112022026508A patent/BR112022026508A2/pt unknown
- 2021-06-23 CA CA3183994A patent/CA3183994A1/en active Pending
- 2021-06-23 KR KR1020237002522A patent/KR20230026489A/ko unknown
- 2021-06-24 AR ARP210101748A patent/AR122736A1/es unknown
- 2021-06-24 TW TW110123220A patent/TW202216773A/zh unknown
-
2023
- 2023-10-26 US US18/384,230 patent/US20240117040A1/en active Pending
- 2023-10-26 US US18/384,223 patent/US20240117039A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
US20230235048A1 (en) | 2023-07-27 |
IL299329A (en) | 2023-02-01 |
WO2021263279A1 (en) | 2021-12-30 |
KR20230026489A (ko) | 2023-02-24 |
EP4171743A1 (en) | 2023-05-03 |
CN116249717A (zh) | 2023-06-09 |
BR112022026508A2 (pt) | 2023-03-07 |
AU2021297540A1 (en) | 2023-02-02 |
TW202216773A (zh) | 2022-05-01 |
US20240117039A1 (en) | 2024-04-11 |
CA3183994A1 (en) | 2021-12-30 |
JP2023533458A (ja) | 2023-08-03 |
US20240117040A1 (en) | 2024-04-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CO2021011140A2 (es) | Anticuerpos que reconocen tau | |
UY38601A (es) | Anticuerpos que reconocen tau | |
CO2019013265A2 (es) | Anticuerpos que reconocen tau | |
CO2018012986A2 (es) | Anticuerpos que reconocen tau | |
CO2018012987A2 (es) | Anticuerpos que reconocen tau | |
CO2021007370A2 (es) | Anticuerpos que reconocen tau | |
CU24446B1 (es) | Un anticuerpo monoclonal humanizado que se une a tau | |
AR122736A1 (es) | Anticuerpos que reconocen sortilina | |
CU20210039A7 (es) | Anticuerpos que reconocen tau | |
CR20170251A (es) | Anticuerpos anti-c5 y métodos para su uso | |
UA45061S (uk) | 1. футляр | |
CL2020002459A1 (es) | Variantes de anticuerpo c-terminales | |
AR128076A1 (es) | Anticuerpos que reconocen la sortilina | |
EA202191306A1 (ru) | Антитела, распознающие тау | |
TR201903527U5 (tr) | Follukta yeni̇li̇k | |
JP1752306S (ja) | 書類ケース | |
JP1745428S (ja) | 書類ケース | |
JP1745431S (ja) | 書類ケース | |
JP1745429S (ja) | 書類ケース | |
UA44765S (uk) | 1. тверде паливо особливе | |
ES1288505Y (es) | Pasta elaborada con gofio | |
JP1761938S (ja) | ノート | |
JP1761936S (ja) | ノート | |
UA42735S (uk) | Гідроакумулятор паливний | |
UA45591S (uk) | 1. бланк документа про вищу освіту тернопільського національного технічного університету імені івана пулюя |