AR122653A1 - Vectores de hvt recombinantes que expresan hemaglutinina de influenza y composiciones inmunogénicas, su producción y usos - Google Patents

Vectores de hvt recombinantes que expresan hemaglutinina de influenza y composiciones inmunogénicas, su producción y usos

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Publication number
AR122653A1
AR122653A1 ARP210101657A ARP210101657A AR122653A1 AR 122653 A1 AR122653 A1 AR 122653A1 AR P210101657 A ARP210101657 A AR P210101657A AR P210101657 A ARP210101657 A AR P210101657A AR 122653 A1 AR122653 A1 AR 122653A1
Authority
AR
Argentina
Prior art keywords
virus
viral vectors
recombinant viral
disease
immunogenic compositions
Prior art date
Application number
ARP210101657A
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English (en)
Inventor
Teshome Mebatsion
Aemro Kassa
Original Assignee
Boehringer Ingelheim Animal Health Usa Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Animal Health Usa Inc filed Critical Boehringer Ingelheim Animal Health Usa Inc
Publication of AR122653A1 publication Critical patent/AR122653A1/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A61K39/255—Marek's disease virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
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    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A61K2039/552—Veterinary vaccine
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    • A61K2039/70—Multivalent vaccine
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  • Health & Medical Sciences (AREA)
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  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
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Abstract

Vectores virales recombinantes y composiciones que incluyen los mismos para usar como vehículos para inducir una respuesta inmunológica. Los vectores virales multivalentes se pueden usar en composiciones o vacunas que contienen uno o más vectores virales recombinantes para la protección contra una variedad de patógenos. La formación de estos vectores virales puede incluir la inserción y expresión de genes extraños para la protección contra una variedad de patógenos. Se proveen además métodos de elaboración y uso de vectores virales recombinantes, así como composiciones inmunogénicas que incluyen los vectores y/o antígenos. En particular, las composiciones inmunogénicas pueden incluir vectores virales recombinantes, tales como vHVT509, vHVT522 y/o vHVT523. Reivindicación 1: Un vector viral recombinante, caracterizado porque comprende: por lo menos una secuencia de ácidos nucleicos derivada de un virus predeterminado seleccionado entre: herpesvirus de pavos (rHVT); virus de la enfermedad de Marek; o herpesvirus de Meleagrid; una primera secuencia de ácidos nucleicos exógena de un virus de la influenza aviar tal que el vector viral recombinante expresará in vivo un antígeno de hemaglutinina del virus de la influenza aviar exógeno; y una segunda secuencia de ácidos nucleicos exógena de una enfermedad aviar que codifica y expresa por lo menos un antígeno de la enfermedad aviar in vivo. Reivindicación 15: La composición de la reivindicación 14, caracterizada porque la cantidad del virus predeterminado, cuando la composición se administra a un ave, es suficiente para inducir una respuesta inmunológica en el ave contra el virus de la enfermedad de Marek y/o el virus de la enfermedad de bursitis infecciosa y/o de la influenza aviar.
ARP210101657A 2020-06-17 2021-06-17 Vectores de hvt recombinantes que expresan hemaglutinina de influenza y composiciones inmunogénicas, su producción y usos AR122653A1 (es)

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EP (1) EP4168043A1 (es)
KR (1) KR20230040328A (es)
CN (1) CN116472057A (es)
AR (1) AR122653A1 (es)
BR (1) BR112022025733A2 (es)
CA (1) CA3186579A1 (es)
CO (1) CO2023000493A2 (es)
IL (1) IL299033A (es)
MA (1) MA58717A1 (es)
MX (1) MX2022016337A (es)
TW (1) TW202214863A (es)
WO (1) WO2021257706A1 (es)

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Publication number Priority date Publication date Assignee Title
WO2017216287A1 (en) 2016-06-17 2017-12-21 Intervet International B.V. Recombinant non-pathogenic marek's disease virus constructs encoding infectious laryngotracheitis virus and infectious bursal disease virus antigens

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IL299033A (en) 2023-02-01
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CN116472057A (zh) 2023-07-21
MX2022016337A (es) 2023-04-10
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CO2023000493A2 (es) 2023-01-26

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