AR121522A1 - ANTICUERPOS CONTRA SARS-Cov-2 (SARS2, COVID-19) - Google Patents

ANTICUERPOS CONTRA SARS-Cov-2 (SARS2, COVID-19)

Info

Publication number
AR121522A1
AR121522A1 ARP210100584A ARP210100584A AR121522A1 AR 121522 A1 AR121522 A1 AR 121522A1 AR P210100584 A ARP210100584 A AR P210100584A AR P210100584 A ARP210100584 A AR P210100584A AR 121522 A1 AR121522 A1 AR 121522A1
Authority
AR
Argentina
Prior art keywords
sars2
cov
antibodies
covid
antibodies against
Prior art date
Application number
ARP210100584A
Other languages
English (en)
Inventor
Franklin Gerardus Grosveld
Dubravka Drabek
Haperen Rien Van
Berend Jan Bosch
Juliette Fedry
Daniel L Hurdiss
Thijs Kuiken
Bartholomeus Leonardus Haagmans
Barry Hubertus Gerardus Rockx
Original Assignee
Harbour Antibodies Bv
Univ Utrecht Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harbour Antibodies Bv, Univ Utrecht Holding Bv filed Critical Harbour Antibodies Bv
Publication of AR121522A1 publication Critical patent/AR121522A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1002—Coronaviridae
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1002—Coronaviridae
    • C07K16/1003—Severe acute respiratory syndrome coronavirus 2 [SARS‐CoV‐2 or Covid-19]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Anticuerpos y fragmentos de unión al antígeno de los mismos que reconocen proteínas de la espícula de SARS-Cov-2 (SARS2-S). En algunas formas de realización, los anticuerpos se unen a SARS2-S con una gran afinidad y/o inhiben una infección por SARS-Cov-2 en células humanas. En algunas formas de realización, los anticuerpos proveen un medio para prevenir, tratar o mejorar una infección por SARS2. En algunas formas de realización, los anticuerpos se usan en ensayos de diagnóstico (por ejemplo, ensayos de serodiagnóstico para SARS2).
ARP210100584A 2020-03-12 2021-03-05 ANTICUERPOS CONTRA SARS-Cov-2 (SARS2, COVID-19) AR121522A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB2003632.3A GB202003632D0 (en) 2020-03-12 2020-03-12 SARS-Cov-2 (SARS2, COVID-19) antibodies

Publications (1)

Publication Number Publication Date
AR121522A1 true AR121522A1 (es) 2022-06-08

Family

ID=70453696

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP210100584A AR121522A1 (es) 2020-03-12 2021-03-05 ANTICUERPOS CONTRA SARS-Cov-2 (SARS2, COVID-19)

Country Status (6)

Country Link
US (2) US20210340225A1 (es)
AR (1) AR121522A1 (es)
GB (5) GB202003632D0 (es)
TW (1) TW202200612A (es)
UY (1) UY39118A (es)
WO (2) WO2021180604A1 (es)

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CN117362422A (zh) * 2020-04-30 2024-01-09 养生堂有限公司 针对SARS-CoV-2的抗体及其用途
WO2021226533A1 (en) 2020-05-08 2021-11-11 Academia Sinica Chimeric influenza vaccines
US20230220053A1 (en) * 2020-05-18 2023-07-13 Elpis Biopharmaceuticals ANTI-SARS-CoV-2 ANTIBODIES AND USES THEREOF
CN112979793B (zh) * 2020-05-27 2022-02-11 江苏省疾病预防控制中心(江苏省公共卫生研究院) 检测新型冠状病毒的抗体
CN111518203B (zh) * 2020-05-27 2021-10-19 江苏省疾病预防控制中心(江苏省公共卫生研究院) 用于新型冠状病毒检测的试剂盒
CN112979790B (zh) * 2020-05-27 2022-02-11 江苏省疾病预防控制中心(江苏省公共卫生研究院) 抗体及在检测新型冠状病毒中的用途
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CN111909260B (zh) * 2020-08-19 2022-06-21 重庆医科大学 新冠病毒rbd特异性单克隆抗体和应用
CN114989293B (zh) * 2020-08-19 2023-10-17 重庆医科大学 新冠病毒rbd特异性单克隆抗体和应用
CN117736313A (zh) * 2020-08-19 2024-03-22 重庆医科大学 新冠病毒rbd特异性单克隆抗体和应用
WO2022101839A1 (en) * 2020-11-12 2022-05-19 Cadila Healthcare Limited Anti-sars-cov-2 monoclonal antibodies and cocktail thereof
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US20230002478A1 (en) * 2021-06-22 2023-01-05 Twist Bioscience Corporation Methods and compositions relating to covid antibody epitopes
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Also Published As

Publication number Publication date
US20210340225A1 (en) 2021-11-04
GB202003632D0 (en) 2020-04-29
US20220017606A1 (en) 2022-01-20
GB202101720D0 (en) 2021-03-24
GB202004340D0 (en) 2020-05-06
TW202200612A (zh) 2022-01-01
WO2021180604A1 (en) 2021-09-16
WO2021180602A1 (en) 2021-09-16
GB202015240D0 (en) 2020-11-11
UY39118A (es) 2021-10-29
GB202013024D0 (en) 2020-10-07

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