AR121226A1 - Compuestos y usos de estos - Google Patents

Compuestos y usos de estos

Info

Publication number
AR121226A1
AR121226A1 ARP210100245A ARP210100245A AR121226A1 AR 121226 A1 AR121226 A1 AR 121226A1 AR P210100245 A ARP210100245 A AR P210100245A AR P210100245 A ARP210100245 A AR P210100245A AR 121226 A1 AR121226 A1 AR 121226A1
Authority
AR
Argentina
Prior art keywords
compounds
compound
formula
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
ARP210100245A
Other languages
English (en)
Inventor
Rishi G Vaswani
David S Huang
Original Assignee
Foghorn Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Foghorn Therapeutics Inc filed Critical Foghorn Therapeutics Inc
Publication of AR121226A1 publication Critical patent/AR121226A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)

Abstract

Reivindicación 1: Un compuesto que tiene la estructura de fórmula (1), o una sal farmacéuticamente aceptable de este.
ARP210100245A 2020-01-29 2021-01-29 Compuestos y usos de estos AR121226A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US202062967359P 2020-01-29 2020-01-29

Publications (1)

Publication Number Publication Date
AR121226A1 true AR121226A1 (es) 2022-04-27

Family

ID=76970694

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP210100245A AR121226A1 (es) 2020-01-29 2021-01-29 Compuestos y usos de estos

Country Status (14)

Country Link
US (3) US11485732B2 (es)
EP (1) EP4096664A4 (es)
JP (1) JP7561195B2 (es)
KR (1) KR20220133258A (es)
CN (1) CN115023226A (es)
AR (1) AR121226A1 (es)
AU (1) AU2021213811A1 (es)
BR (1) BR112022015004A2 (es)
CA (1) CA3167275A1 (es)
CO (1) CO2022010547A2 (es)
IL (1) IL295100A (es)
MX (1) MX2022009309A (es)
WO (1) WO2021155262A1 (es)
ZA (1) ZA202207804B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112153984A (zh) 2018-01-30 2020-12-29 福宏治疗公司 化合物及其用途
WO2020160100A1 (en) * 2019-01-29 2020-08-06 Foghorn Therapeutics Inc. Compounds and uses thereof
EP4153176A4 (en) * 2020-05-20 2024-05-29 Foghorn Therapeutics Inc. METHODS OF TREATING CANCER
US20240158387A1 (en) * 2021-03-09 2024-05-16 Foghorn Therapeutics Inc. Crystalline forms, compositions containing same, and methods of their use
CN117337179A (zh) * 2021-03-19 2024-01-02 福宏治疗公司 Brg1和brm的酶活性抑制剂的治疗方案
EP4376886A2 (en) * 2021-07-29 2024-06-05 Foghorn Therapeutics Inc. Methods of treating cancer
WO2023196560A1 (en) * 2022-04-08 2023-10-12 Foghorn Therapeutics Inc. Methods of treating cancer
WO2023196565A1 (en) * 2022-04-08 2023-10-12 Foghorn Therapeutics, Inc. Methods of treating cancer
WO2024125543A1 (zh) * 2022-12-16 2024-06-20 苏州科睿思制药有限公司 达洛色替的晶型及其制备方法和用途

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US20050079512A1 (en) 2003-02-26 2005-04-14 Emerson Beverly M. Methods of modulating gene expression
EP2148678A4 (en) 2007-05-23 2010-08-04 Siga Technologies Inc ANTIVIRAL DRUGS FOR THE TREATMENT AND PREVENTION OF DENGUE INFECTION
CN103038231B (zh) 2010-03-17 2016-04-20 泰纬生命科技股份有限公司 Hec1活性调节剂及其方法
US9410943B2 (en) 2013-03-14 2016-08-09 The Board Of Trustees Of The Leland Stanford Junior University Methods, compositions and screens for therapeutics for the treatment of synovial sarcoma
EP2968318A4 (en) 2013-03-15 2016-12-14 Shifa Biomedical Corp ANTI-PCSK9 COMPOUNDS AND METHODS FOR TREATING AND / OR PREVENTING CARDIOVASCULAR DISEASES
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WO2015046193A1 (ja) 2013-09-25 2015-04-02 塩野義製薬株式会社 Trpv4阻害活性を有する芳香族複素環式アミン誘導体
EP3102193B1 (en) * 2014-02-06 2023-01-11 Rutgers, The State University of New Jersey Antibacterial agents: n(alpha)-aroyl-n-aryl-phenylalaninamides
MA41598A (fr) 2015-02-25 2018-01-02 Constellation Pharmaceuticals Inc Composés thérapeutiques de pyridazine et leurs utilisations
US20180328913A1 (en) 2015-11-19 2018-11-15 Dana-Farber Cancer Institute, Inc. Methods of identifying compounds that interfere with erg-driven misguidance of baf complexes in tmprss2-erg driven prostate cancers
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CN112153984A (zh) 2018-01-30 2020-12-29 福宏治疗公司 化合物及其用途
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JP7328323B2 (ja) 2018-08-17 2023-08-16 ノバルティス アーゲー SMARCA2/BRM ATPase阻害剤としての尿素化合物及び組成物
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WO2020160100A1 (en) 2019-01-29 2020-08-06 Foghorn Therapeutics Inc. Compounds and uses thereof
US20230079819A1 (en) 2019-01-29 2023-03-16 Foghorn Therapeutics Inc. Compounds and uses thereof
WO2021081032A1 (en) 2019-10-25 2021-04-29 Dana-Farber Cancer Institute, Inc. Compositions comprising modified smarcb1 and uses thereof
EP4096668A4 (en) 2020-01-29 2024-02-28 Foghorn Therapeutics Inc. COMPOUNDS AND THEIR USES
WO2021183218A1 (en) 2020-03-13 2021-09-16 Dana-Farber Cancer Institute, Inc. Compositions and methods for modulating the interaction between ss18-ssx fusion oncoprotein and nucleosomes

Also Published As

Publication number Publication date
US20240101550A1 (en) 2024-03-28
WO2021155262A1 (en) 2021-08-05
EP4096664A4 (en) 2024-02-28
ZA202207804B (en) 2023-12-20
US20210230154A1 (en) 2021-07-29
CA3167275A1 (en) 2021-08-05
EP4096664A1 (en) 2022-12-07
US11485732B2 (en) 2022-11-01
TW202136252A (zh) 2021-10-01
KR20220133258A (ko) 2022-10-04
JP7561195B2 (ja) 2024-10-03
IL295100A (en) 2022-09-01
BR112022015004A2 (pt) 2022-09-20
CO2022010547A2 (es) 2022-09-09
US20230129003A1 (en) 2023-04-27
CN115023226A (zh) 2022-09-06
AU2021213811A1 (en) 2022-07-28
MX2022009309A (es) 2022-08-22
JP2023512039A (ja) 2023-03-23

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