AR119867A1 - Gonadotrofina coriónica recombinante, procedimiento para su preparación, composiciones farmacéuticas y usos de la misma - Google Patents
Gonadotrofina coriónica recombinante, procedimiento para su preparación, composiciones farmacéuticas y usos de la mismaInfo
- Publication number
- AR119867A1 AR119867A1 ARP200102435A ARP200102435A AR119867A1 AR 119867 A1 AR119867 A1 AR 119867A1 AR P200102435 A ARP200102435 A AR P200102435A AR P200102435 A ARP200102435 A AR P200102435A AR 119867 A1 AR119867 A1 AR 119867A1
- Authority
- AR
- Argentina
- Prior art keywords
- recombinant
- gonadotrophine
- procedure
- preparation
- pharmaceutical compositions
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 102000011022 Chorionic Gonadotropin Human genes 0.000 abstract 2
- 108010062540 Chorionic Gonadotropin Proteins 0.000 abstract 2
- 241000283073 Equus caballus Species 0.000 abstract 1
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 229940015047 chorionic gonadotropin Drugs 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 230000013595 glycosylation Effects 0.000 abstract 1
- 238000006206 glycosylation reaction Methods 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Reproductive Health (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
La presente está relacionada a un polipéptido recombinante de gonadotrofina coriónica de cadena simple que tiene una secuencia de aminoácidos que codifica la cadena b y a de la gonadotrofina coriónica equina unida a una o más secuencias que incluyen sitios de glicosilación, que resulta en una excelente actividad in vitro e in vivo. También se enseñan las moléculas de ADN que codifican el polipéptido recombinante, un vector de expresión que comprende estas moléculas de ADN, las composiciones que comprende la proteína recombinante y los métodos para prepararlas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2019/073277 WO2021037384A1 (en) | 2019-08-30 | 2019-08-30 | Recombinant chorionic gonadotropin, procedure for preparation, pharmaceutical compositions and uses of the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR119867A1 true AR119867A1 (es) | 2022-01-19 |
Family
ID=67875429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP200102435A AR119867A1 (es) | 2019-08-30 | 2020-08-28 | Gonadotrofina coriónica recombinante, procedimiento para su preparación, composiciones farmacéuticas y usos de la misma |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220289810A1 (es) |
| EP (1) | EP4021930A1 (es) |
| JP (1) | JP2022546427A (es) |
| KR (1) | KR20220053003A (es) |
| CN (1) | CN114391020A (es) |
| AR (1) | AR119867A1 (es) |
| AU (1) | AU2019464037B2 (es) |
| BR (1) | BR112022003575A2 (es) |
| CA (1) | CA3149596A1 (es) |
| UY (1) | UY38862A (es) |
| WO (1) | WO2021037384A1 (es) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4334615B2 (ja) * | 1994-08-12 | 2009-09-30 | ワシントン・ユニバーシティ | 糖タンパク質ホルモンカルテットの一本鎖形態 |
| EP0974599A4 (en) * | 1996-11-12 | 2002-06-12 | Teikoku Hormone Mfg Co Ltd | EQUINE, SINGLE-STRANDED AND RECOMBINANT CHORIONIC GONADOTROPHIN |
| US6103501A (en) * | 1997-11-17 | 2000-08-15 | Washington University | Single chain glycoprotein hormones comprising two β and one α subunits and recombinant production thereof |
| US7553941B2 (en) * | 2006-02-03 | 2009-06-30 | Modigene Inc | Long-acting polypeptides and methods of producing same |
| US8835386B2 (en) * | 2007-11-30 | 2014-09-16 | Venaxis, Inc. | Activity of recombinant equine follicle stimulating hormone |
| BR102015032660B1 (pt) | 2015-12-28 | 2019-05-28 | Ouro Fino Saúde Animal Participações S.A. | PROCESSO DE PRODUÇÃO DE UMA GONADOTROFINA CORIÔNICA EQUINA RECOMBINANTE (reCG): COMPOSIÇÃO VETERINÁRIA E USO |
-
2019
- 2019-08-30 CN CN201980099898.3A patent/CN114391020A/zh active Pending
- 2019-08-30 CA CA3149596A patent/CA3149596A1/en active Pending
- 2019-08-30 US US17/638,118 patent/US20220289810A1/en active Pending
- 2019-08-30 BR BR112022003575A patent/BR112022003575A2/pt unknown
- 2019-08-30 WO PCT/EP2019/073277 patent/WO2021037384A1/en unknown
- 2019-08-30 JP JP2022513230A patent/JP2022546427A/ja active Pending
- 2019-08-30 KR KR1020227010240A patent/KR20220053003A/ko unknown
- 2019-08-30 AU AU2019464037A patent/AU2019464037B2/en active Active
- 2019-08-30 EP EP19765423.9A patent/EP4021930A1/en active Pending
-
2020
- 2020-08-26 UY UY0001038862A patent/UY38862A/es unknown
- 2020-08-28 AR ARP200102435A patent/AR119867A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN114391020A (zh) | 2022-04-22 |
| JP2022546427A (ja) | 2022-11-04 |
| CA3149596A1 (en) | 2021-03-04 |
| EP4021930A1 (en) | 2022-07-06 |
| UY38862A (es) | 2021-01-29 |
| AU2019464037B2 (en) | 2023-06-15 |
| WO2021037384A1 (en) | 2021-03-04 |
| BR112022003575A2 (pt) | 2022-05-24 |
| US20220289810A1 (en) | 2022-09-15 |
| KR20220053003A (ko) | 2022-04-28 |
| AU2019464037A1 (en) | 2022-03-24 |
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